PDB: 243911 件ウェブページステータス検索Chemie searchBIRD

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6N32	Anti-HIV-1 Fab 2G12 re-refinement 分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, SULFATE ION 著者 Calarese, D.A, Stanfield, R.L, Wilson, I.A. 登録日 2018-11-14 公開日 2018-11-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
6N3O	Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents 分子名称: N-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide, eIF-2-alpha kinase GCN2 著者 Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R. 登録日 2018-11-15 公開日 2019-10-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode. Acs Med.Chem.Lett., 10, 2019
6N3X	Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[1-Benzyl]Carbamoyl Guanosine 分子名称: 1,2-ETHANEDIOL, 5'-O-(benzylcarbamoyl)guanosine, CHLORIDE ION, ... 著者 Strom, A.M, Finzel, B.C. 登録日 2018-11-16 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chem Neurosci, 10, 2019
4N0I	Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine 分子名称: GLUTAMINE, Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, ... 著者 Araiso, Y, Ishitani, R, Nureki, O. 登録日 2013-10-02 公開日 2014-04-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases Nucleic Acids Res., 42, 2014
6N5N	Structure of Human pir-miRNA-208a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... 著者 Shoffner, G.M, Peng, Z, Guo, F. 登録日 2018-11-22 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.951 Å) 主引用文献 Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
4N92	Crystal structure of beta-lactamse PenP_E166S 分子名称: Beta-lactamase 著者 Pan, X, Wong, W, Zhao, Y. 登録日 2013-10-19 公開日 2014-09-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
6N52	Metabotropic Glutamate Receptor 5 Apo Form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 著者 Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. 登録日 2018-11-20 公開日 2019-01-23 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
6N6A	Vibrio cholerae Oligoribonuclease bound to pGG 分子名称: Oligoribonuclease, RNA (5'-R(P*GP*G)-3'), SODIUM ION 著者 Lormand, J.D, Sondermann, H. 登録日 2018-11-26 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation. Elife, 8, 2019
4N1E	Structural evidence for antigen receptor evolution 分子名称: Lysozyme C, immunoglobulin variable light chain domain 著者 Langley, D.B, Rouet, R, Stock, D, Christ, D. 登録日 2013-10-04 公開日 2014-10-29 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural reconstruction of protein ancestry. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6N6G	Vibrio cholerae Oligoribonuclease bound to pCG 分子名称: Oligoribonuclease, RNA (5'-R(P*CP*G)-3'), SODIUM ION 著者 Lormand, J.D, Sondermann, H. 登録日 2018-11-26 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.018 Å) 主引用文献 A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation. Elife, 8, 2019
6N6O	Crystal structure of the human TTK in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, 4-({5-chloro-4-[(cis-4-hydroxy-4-methylcyclohexyl)oxy]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}amino)-N,N-dimethyl-3-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}benzamide, Dual specificity protein kinase TTK, ... 著者 Fenalti, G. 登録日 2018-11-26 公開日 2019-05-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. J.Med.Chem., 62, 2019
6N5Q	Structure of Human pir-miRNA-378a Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ... 著者 Shoffner, G.M, Peng, Z, Guo, F. 登録日 2018-11-22 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
6N73	Crystal Structure of ATPase delta1-79 Spa47 R271A 分子名称: ATP synthase SpaL/MxiB 著者 Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E. 登録日 2018-11-27 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.398 Å) 主引用文献 Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation. Proteins, 87, 2019
4N5U	Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240] 分子名称: Receptor-type tyrosine-protein phosphatase F, SULFATE ION 著者 Kumar, P.R, Banu, R, Bhosle, R, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Glenn, A.S, Hillerich, B, Khafizov, K, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) 登録日 2013-10-10 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.456 Å) 主引用文献 Crystal structure of the 4th FN3 domain of human PTP, receptor F [PSI-NYSGRC-006240] to be published
6N9A	Crystal Structure of Thermotoga maritima threonylcarbamoyladenosine biosynthesis complex TsaB2D2E2 bound to ATP and carboxy-AMP 分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, 5'-O-[(R)-(carboxyoxy)(hydroxy)phosphoryl]adenosine, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Swairjo, M.A, Stec, B. 登録日 2018-12-01 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational communication mediates the reset step in t6A biosynthesis. Nucleic Acids Res., 47, 2019
6N8A	Crystal structure of selenomethionine-containing AcaB from uropathogenic E. coli 分子名称: CHLORIDE ION, transcription regulator AcaB 著者 Luo, Z, Hancock, S.J, Schembri, M.A, Kobe, B. 登録日 2018-11-28 公開日 2020-07-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.4011 Å) 主引用文献 Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nat Microbiol, 5, 2020
6N90	YoeB/ParE toxin from Agrobacterium tumefaciens 分子名称: 6-tungstotellurate(VI), Uncharacterized protein 著者 Bourne, C.R, Reddem, E.R. 登録日 2018-11-30 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 Identifying a Molecular Mechanism That Imparts Species-Specific Toxicity to YoeB Toxins. Front Microbiol, 11, 2020
4N7H	Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 分子名称: Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE 著者 Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. 登録日 2013-10-15 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014
6N97	Methylmalonyl-CoA decarboxylase in complex with 2-sulfonate-propionyl-amino(dethia)-CoA 分子名称: (2R)-sulfonatepropionyl-amino(dethia)-CoA, (2S)-sulfonatepropionyl-amino(dethia)-CoA, IMIDAZOLE, ... 著者 Stunkard, L.M, Dixon, A.D, Huth, T.J, Lohman, J.R. 登録日 2018-11-30 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Sulfonate/Nitro Bearing Methylmalonyl-Thioester Isosteres Applied to Methylmalonyl-CoA Decarboxylase Structure-Function Studies. J. Am. Chem. Soc., 141, 2019
4N7N	Capturing the haemoglobin allosteric transition in a single crystal form; Crystal structure of full-liganded human haemoglobin with phosphate at 2.75 A resolution. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugiyama, K, Shibayama, N, Park, S.Y. 登録日 2013-10-16 公開日 2014-04-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.754 Å) 主引用文献 Capturing the hemoglobin allosteric transition in a single crystal form J.Am.Chem.Soc., 136, 2014
4N21	Crystal structure of the GP2 Core Domain from the California Academy of Science Virus 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain 著者 Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-10-04 公開日 2013-11-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J.Mol.Biol., 426, 2014
4MSW	Y78 ester mutant of KcsA in high K+ 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, DIACYL GLYCEROL, Monoclonal 11D8 anti-human butyrylcholinesterase (BChE) light chain, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2013-09-18 公開日 2013-10-30 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Using protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K+ channels. Proc.Natl.Acad.Sci.USA, 110, 2013
4N3D	Crystal structure of the dimeric variant EGFP-K162Q in P61 space group 分子名称: GLYCEROL, Green fluorescent protein, PHOSPHATE ION, ... 著者 Pletneva, N.V, Pletnev, V.Z, Pletnev, S.V. 登録日 2013-10-07 公開日 2014-08-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Three dimensional structure of the dimeric gene-engineered variant of green fluorescent protein egfp-K162Q in P61 crystal space group Rus.J.Bioorg.Chem., 40, 2014
4MUD	Crystal structure of a ring oxydation complex/ phenylacetic acid degradation-like protein (SSO1313) from Sulfolobus solfataricus P2 at 2.43 A resolution 分子名称: 1,2-ETHANEDIOL, Ring oxydation complex/ phenylacetic acid degradation related protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-09-21 公開日 2013-10-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Crystal structure of a ring oxydation complex/ phenylacetic acid degradation-like protein (SSO1313) from Sulfolobus solfataricus P2 at 2.43 A resolution To be published
6NCR	Crystal Structure of Tryptophan-tRNA ligase from Chlamydia trachomatis with bound L-tryptophan 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-12-12 公開日 2018-12-26 最終更新日 2025-10-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Tryptophan-tRNA ligase from Chlamydia trachomatis with bound L-tryptophan to be published

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