7CN8
 
 | | Cryo-EM structure of PCoV_GX spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | | 著者 | Wang, X, Yu, J, Zhang, S, Qiao, S, Zeng, J, Tian, L. | | 登録日 | 2020-07-30 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution.
Nat Commun, 12, 2021
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1BWA
 | | HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | | 分子名称: | PROTEIN (HIV-1 PROTEASE), [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-3,3'-[[TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-D IYL] BIS(METHYLENE)]BIS[N-2-THIAZOLYLBENZAMIDE] | | 著者 | Ala, P, Chang, C.H. | | 登録日 | 1998-09-22 | | 公開日 | 1998-10-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities.
Biochemistry, 37, 1998
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1BO4
 | | CRYSTAL STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE: SERRATIA MARESCENS AMINOGLYCOSIDE 3-N-ACETYLTRANSFERASE | | 分子名称: | COENZYME A, PROTEIN (SERRATIA MARCESCENS AMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE), SPERMIDINE | | 著者 | Wolf, E, Vassilev, A, Makino, Y, Sali, A, Nakatani, Y, Burley, S.K. | | 登録日 | 1998-08-08 | | 公開日 | 1998-10-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase.
Cell(Cambridge,Mass.), 94, 1998
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1BX3
 | | EFFECTS OF COMMONLY USED CRYOPROTECTANTS ON GLYCOGEN PHOSPHORYLASE ACTIVITY AND STRUCTURE | | 分子名称: | PROTEIN (GLYCOGEN PHOSPHORYLASE B), PYRIDOXAL-5'-PHOSPHATE | | 著者 | Tsitsanou, K.E, Oikonomakos, N.G, Zographos, S.E, Skamnaki, V.T, Gregoriou, M, Watson, K.A, Johnson, L.N, Fleet, G.W.J. | | 登録日 | 1999-10-13 | | 公開日 | 1999-10-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
Protein Sci., 8, 1999
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1BOQ
 | | PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | | 分子名称: | PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION | | 著者 | Peters, R.J, Shiau, A.K, Sohl, J.L, Anderson, D.E, Tang, G, Silen, J.L, Agard, D.A. | | 登録日 | 1998-08-05 | | 公開日 | 1998-08-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease.
Biochemistry, 37, 1998
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1BP0
 | | THYMIDYLATE SYNTHASE R23I MUTANT | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, POTASSIUM ION, PROTEIN (THYMIDYLATE SYNTHASE) | | 著者 | Morse, R, Finer-Moore, J, Stroud, R.M. | | 登録日 | 1998-08-11 | | 公開日 | 2000-01-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance".
Biochemistry, 39, 2000
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5GK5
 | | Apo structure of fructose 1,6-bisphosphate aldolase from Escherichia coli at 1.9 angstrom resolution | | 分子名称: | DI(HYDROXYETHYL)ETHER, Fructose-bisphosphate aldolase class 2, GLYCEROL, ... | | 著者 | Tran, T.H, Huynh, K.H, Ho, T.H, Kang, L.W. | | 登録日 | 2016-07-03 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Apo structure of fructose 1,6-bisphosphate aldolase from Escherichia coli at 1.9 angstrom resolution
To Be Published
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7AJP
 | | Crystal Structure of Human Adenovirus 56 Fiber Knob | | 分子名称: | 1,2-ETHANEDIOL, Fiber, GLYCEROL, ... | | 著者 | Strebl, M, Mindler, K, Stehle, T. | | 登録日 | 2020-09-29 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.382018 Å) | | 主引用文献 | Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46.
Proc.Natl.Acad.Sci.USA, 118, 2021
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1EYM
 | | FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX | | 分子名称: | FK506 BINDING PROTEIN | | 著者 | Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T. | | 登録日 | 2000-05-07 | | 公開日 | 2000-08-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A ligand-reversible dimerization system for controlling protein-protein interactions.
Proc.Natl.Acad.Sci.USA, 97, 2000
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5O60
 | | Structure of the 50S large ribosomal subunit from Mycobacterium smegmatis | | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | | 著者 | Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N. | | 登録日 | 2017-06-02 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | The Complete Structure of the Mycobacterium smegmatis 70S Ribosome.
Cell Rep, 20, 2017
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1E8N
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1EMC
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1E94
 | | HslV-HslU from E.coli | | 分子名称: | HEAT SHOCK PROTEIN HSLU, HEAT SHOCK PROTEIN HSLV, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Song, H.K, Hartmann, C, Ravishankar, R, Bochtler, M. | | 登録日 | 2000-10-07 | | 公開日 | 2000-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mutational Studies on Hslu and its Docking Mode with Hslv
Proc.Natl.Acad.Sci.USA, 97, 2000
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5O3K
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1EV1
 | | ECHOVIRUS 1 | | 分子名称: | ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID | | 著者 | Wien, M.W, Filman, D.J, Hogle, J.M. | | 登録日 | 1997-12-02 | | 公開日 | 1999-01-27 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | Structure determination of echovirus 1.
Acta Crystallogr.,Sect.D, 54, 1998
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1EAK
 | | Catalytic domain of proMMP-2 E404Q mutant | | 分子名称: | 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, INHIBITOR PEPTIDE, ... | | 著者 | Bergmann, U, Tuuttila, A, Tryggvason, K, Morgunova, E. | | 登録日 | 2001-07-12 | | 公開日 | 2002-08-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Crystal Structure of Human Mmp-2 Reveals a New P
To be Published
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5O5L
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5H2F
 | | Crystal structure of the PsbM-deletion mutant of photosystem II | | 分子名称: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | | 著者 | Uto, S, Kawakami, K, Umena, Y, Iwai, M, Ikeuchi, M, Shen, J.R, Kamiya, N. | | 登録日 | 2016-10-15 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutual relationships between structural and functional changes in a PsbM-deletion mutant of photosystem II.
Faraday Discuss., 198, 2017
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1E9L
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1E9X
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1EB7
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1EEO
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 | | 分子名称: | ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B | | 著者 | Sarmiento, M, Puius, Y.A, Vetter, S.W, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. | | 登録日 | 2000-02-01 | | 公開日 | 2001-02-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
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5O9A
 | | Crystal structure of the GluA2 ligand-binding domain (S1S2J-L504Y-N775S) in complex with glutamate and BPAM121 at 1.78 A resolution | | 分子名称: | 1,2-ETHANEDIOL, 7-chloro-4-(2-fluoroethyl)-2,3-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, CHLORIDE ION, ... | | 著者 | Laulumaa, S, Rovinskaja, K, Frydenvang, K.A, Kastrup, J.S. | | 登録日 | 2017-06-16 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | 7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency.
J. Med. Chem., 61, 2018
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1EFO
 | | CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG) | | 分子名称: | DNA (5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3') | | 著者 | Sudarsanakumar, C, Xiong, Y, Sundaralingam, M. | | 登録日 | 2000-02-09 | | 公開日 | 2000-05-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag).
J.Mol.Biol., 299, 2000
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5HPW
 | | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Singh, R.P, Singh, A, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2016-01-21 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination
To Be Published
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