2B73
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![BU of 2b73 by Molmil](/molmil-images/mine/2b73) | T4 Lysozyme mutant L99A at 100 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B74
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![BU of 2b74 by Molmil](/molmil-images/mine/2b74) | T4 Lysozyme mutant L99A at 100 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B75
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![BU of 2b75 by Molmil](/molmil-images/mine/2b75) | T4 Lysozyme mutant L99A at 150 MPa | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B76
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![BU of 2b76 by Molmil](/molmil-images/mine/2b76) | E. coli Quinol fumarate reductase FrdA E49Q mutation | 分子名称: | CITRATE ANION, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Maklashina, E, Iverson, T.M, Sher, Y, Kotlyar, V, Mirza, O, Andrell, J, Hudson, J.M, Armstrong, F.A, Cecchini, G. | 登録日 | 2005-10-03 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Fumarate Reductase and Succinate Oxidase Activity of Escherichia coli Complex II Homologs Are Perturbed Differently by Mutation of the Flavin Binding Domain J.Biol.Chem., 281, 2006
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2B77
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![BU of 2b77 by Molmil](/molmil-images/mine/2b77) | Human transthyretin (TTR) complexed with Diflunisal analogues- TTR.2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID | 分子名称: | 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID, Transthyretin | 著者 | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | 登録日 | 2005-10-03 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis. J.Med.Chem., 47, 2004
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2B78
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2B7A
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![BU of 2b7a by Molmil](/molmil-images/mine/2b7a) | The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor | 分子名称: | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase JAK2 | 著者 | Lucet, I.S, Fantino, E, Styles, M, Bamert, R, Patel, O, Broughton, S.E, Walter, M, Burns, C.J, Treutlein, H, Wilks, A.F, Rossjohn, J. | 登録日 | 2005-10-04 | 公開日 | 2006-01-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood, 107, 2006
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2B7B
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![BU of 2b7b by Molmil](/molmil-images/mine/2b7b) | Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP | 分子名称: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta | 著者 | Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G. | 登録日 | 2005-10-04 | 公開日 | 2006-05-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha J.Biol.Chem., 281, 2006
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2B7C
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![BU of 2b7c by Molmil](/molmil-images/mine/2b7c) | Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A | 分子名称: | Elongation factor 1-alpha, elongation factor-1 beta | 著者 | Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G. | 登録日 | 2005-10-04 | 公開日 | 2006-05-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha J.Biol.Chem., 281, 2006
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2B7D
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![BU of 2b7d by Molmil](/molmil-images/mine/2b7d) | Factor VIIa Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, and Efficacy in a Baboon Thrombosis Model | 分子名称: | (2R)-2-[5-(5-CARBAMIMIDOYL-1H-BENZOIMIDAZOL-2-YL)-6,2'-DIHYDROXY-5'-UREIDOMETHYL-BIPHENYL-3-YL]-SUCCINIC ACID, Coagulation factor VII, Tissue factor | 著者 | Young, W.B, Mordenti, J, Torkelson, S, Shrader, W.D, Kolesnikov, A, Rai, R, Liu, L, Hu, H, Leahy, E.M, Green, M.J, Sprengeler, P.A, Katz, B.A, Yu, C, Janc, J.W, Elrod, K.C, Marzec, U.M, Hanson, S.R. | 登録日 | 2005-10-04 | 公開日 | 2006-02-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model. Bioorg.Med.Chem.Lett., 16, 2006
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2B7E
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![BU of 2b7e by Molmil](/molmil-images/mine/2b7e) | First FF domain of Prp40 Yeast Protein | 分子名称: | Pre-mRNA processing protein PRP40 | 著者 | Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J. | 登録日 | 2005-10-04 | 公開日 | 2005-11-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains. J.Biol.Chem., 281, 2006
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2B7F
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![BU of 2b7f by Molmil](/molmil-images/mine/2b7f) | Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design | 分子名称: | (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION | 著者 | Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A. | 登録日 | 2005-10-04 | 公開日 | 2005-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B7G
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2B7H
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![BU of 2b7h by Molmil](/molmil-images/mine/2b7h) | Hemoglobin from Cerdocyon thous, a canidae from Brazil, at 2.2 Angstroms resolution | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, hemoglobin alpha chain, ... | 著者 | Esteves, G.F, Silva, V.C, Bloch Jr, C, Medrano, F.J, Barbosa, J.A.R.G, Freitas, S.M. | 登録日 | 2005-10-04 | 公開日 | 2006-09-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure and biophysical characterization of the Cerdocyon thous, a Canidae from Brazil. To be Published
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2B7J
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2B7K
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2B7L
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![BU of 2b7l by Molmil](/molmil-images/mine/2b7l) | Crystal Structure of CTP:Glycerol-3-Phosphate Cytidylyltransferase from Staphylococcus aureus | 分子名称: | glycerol-3-phosphate cytidylyltransferase | 著者 | Fong, D.H, Yim, V.C.-N, D'Elia, M.A, Brown, E.D, Berghuis, A.M. | 登録日 | 2005-10-04 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: examination of structural basis for kinetic mechanism. Biochim.Biophys.Acta, 1764, 2006
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2B7M
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2B7N
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![BU of 2b7n by Molmil](/molmil-images/mine/2b7n) | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori | 分子名称: | Probable nicotinate-nucleotide pyrophosphorylase, QUINOLINIC ACID, SULFATE ION | 著者 | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | 登録日 | 2005-10-04 | 公開日 | 2006-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori Proteins, 63, 2006
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2B7O
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![BU of 2b7o by Molmil](/molmil-images/mine/2b7o) | The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis | 分子名称: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, O-DODECANYL OCTAETHYLENE GLYCOL, ... | 著者 | Webby, C.J, Baker, H.M, Lott, J.S, Baker, E.N, Parker, E.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | 登録日 | 2005-10-05 | 公開日 | 2005-10-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes J.Mol.Biol., 354, 2005
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2B7P
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![BU of 2b7p by Molmil](/molmil-images/mine/2b7p) | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with phthalic acid | 分子名称: | PHTHALIC ACID, Probable nicotinate-nucleotide pyrophosphorylase, SULFATE ION | 著者 | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | 登録日 | 2005-10-05 | 公開日 | 2006-02-14 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori Proteins, 63, 2006
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2B7Q
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![BU of 2b7q by Molmil](/molmil-images/mine/2b7q) | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with nicotinate mononucleotide | 分子名称: | NICOTINATE MONONUCLEOTIDE, Probable nicotinate-nucleotide pyrophosphorylase | 著者 | Kim, M.K, Im, Y.J, Lee, J.H, Eom, S.H. | 登録日 | 2005-10-05 | 公開日 | 2006-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori Proteins, 63, 2006
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2B7R
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![BU of 2b7r by Molmil](/molmil-images/mine/2b7r) | Structure of E378D mutant flavocytochrome c3 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARIC ACID, Fumarate reductase flavoprotein subunit, ... | 著者 | Pankhurst, K.L, Mowat, C.G, Rothery, E.L, Miles, C.S, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | 登録日 | 2005-10-05 | 公開日 | 2006-05-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A Proton Delivery Pathway in the Soluble Fumarate Reductase from Shewanella frigidimarina. J.Biol.Chem., 281, 2006
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2B7S
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![BU of 2b7s by Molmil](/molmil-images/mine/2b7s) | R381K mutant of flavocytochrome c3 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARIC ACID, Fumarate reductase flavoprotein subunit, ... | 著者 | Pankhurst, K.L, Mowat, C.G, Rothery, E.L, Miles, C.S, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | 登録日 | 2005-10-05 | 公開日 | 2006-05-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A Proton Delivery Pathway in the Soluble Fumarate Reductase from Shewanella frigidimarina. J.Biol.Chem., 281, 2006
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2B7T
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![BU of 2b7t by Molmil](/molmil-images/mine/2b7t) | Structure of ADAR2 dsRBM1 | 分子名称: | Double-stranded RNA-specific editase 1 | 著者 | Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T. | 登録日 | 2005-10-05 | 公開日 | 2006-03-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure, 14, 2006
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