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1A48
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SAICAR SYNTHASE
分子名称: PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, SULFATE ION
著者Levdikov, V.M, Melik-Adamyan, W.R, Lamzin, V.S, Wilson, K.S.
登録日1998-02-12
公開日1999-03-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis.
Structure, 6, 1998
3G7Y
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Crystal structure of oxidized Ost6L
分子名称: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6
著者Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M.
登録日2009-02-11
公開日2009-06-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.215 Å)
主引用文献Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
3JA8
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Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
4Z2Z
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New crystal structure of yeast Ddi1 aspartyl protease reveals substrate engagement mode
分子名称: DNA damage-inducible protein 1
著者Trempe, J.-F, Feng, X, Gehring, K.
登録日2015-03-30
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
5IC7
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Structure of the WD domain of UTP18
分子名称: Putative uncharacterized protein, SULFATE ION
著者Zhang, C, Ye, K.
登録日2016-02-22
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.331 Å)
主引用文献Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
4OFB
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Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
分子名称: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
著者Sun, L, Edwards, R.A, Glover, J.N.M.
登録日2014-01-14
公開日2015-04-15
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
6AWL
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Crystal structure of human Coq9
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, ...
著者Bingman, C.A, Lohman, D.C, Smith, R.W, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP)
登録日2017-09-05
公開日2019-02-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis.
Mol. Cell, 73, 2019
5UK3
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Crystal structure of cyanase from T. urticae
分子名称: Uncharacterized protein
著者Schlachter, C.R, Chruszcz, M.
登録日2017-01-19
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Characterization of a Eukaryotic Cyanase from Tetranychus urticae.
J. Agric. Food Chem., 65, 2017
5G3N
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Discovery of a novel secreted phospholipase A2 (sPLA2) inhibitor.
分子名称: 3-(5'-BENZYL-2'-CARBAMOYLBIPHENYL-3-YL)PROPANOIC ACID, CALCIUM ION, FORMIC ACID, ...
著者Sandmark, J, Bodin, C, Hallberg, K.
登録日2016-04-29
公開日2016-09-14
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of Azd2716: A Novel Secreted Phospholipase A2 (Spla2) Inhibitor for the Treatment of Coronary Artery Disease
Acs Med.Chem.Lett., 7, 2016
4BGL
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Superoxide reductase (Neelaredoxin) from Archaeoglobus fulgidus
分子名称: FE (III) ION, GLYCEROL, SUPEROXIDE REDUCTASE
著者Bandeiras, T.M, Rodrigues, J.V, Sousa, C.M, Barradas, A.R, Pinho, F.G, Pinto, A.F, Teixeira, M, Matias, P.M, Romao, C.V.
登録日2013-03-27
公開日2014-04-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Superoxide Reductase from Giardia Intestinalis: Structural Characterization of the First Sor from a Eukaryotic Organism Shows an Iron Centre that is Highly Sensitive to Photoreduction
Acta Crystallogr.,Sect.D, 71, 2015
6QX6
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Structure of gtPebB-dihydrobiliverdin complex
分子名称: 15,16-DIHYDROBILIVERDIN, Ferredoxin bilin reductase plastid, PENTAETHYLENE GLYCOL, ...
著者Sommerkamp, J.A, Hofmann, E.
登録日2019-03-07
公開日2019-08-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the first eukaryotic bilin reductaseGtPEBB reveals a flipped binding mode of dihydrobiliverdin.
J.Biol.Chem., 294, 2019
5IC9
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Structure of the CTD complex of Utp12 and Utp13
分子名称: Putative uncharacterized protein
著者Zhang, C, Ye, K.
登録日2016-02-23
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
5ICA
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Structure of the CTD complex of UTP12, Utp13, Utp1 and Utp21
分子名称: Periodic tryptophan protein 2-like protein, Putative U3 snoRNP protein, Putative uncharacterized protein
著者Zhang, C, Ye, K.
登録日2016-02-23
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.507 Å)
主引用文献Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
5UPJ
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HIV-2 PROTEASE/U99283 COMPLEX
分子名称: 5,6,7,8,9,10-HEXAHYDRO-4-HYDROXY-3-(1-PHENYLPROPYL)CYCLOOCTA[B]PYRAN-2-ONE, HIV-2 PROTEASE
著者Watenpaugh, K.D, Mulichak, A.M, Finzel, B.C.
登録日1996-12-10
公開日1997-04-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors.
J.Med.Chem., 38, 1995
8WCQ
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Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in intermediate state
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel
著者Bharambe, N, Li, Z, Basak, S.
登録日2023-09-13
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.
Nat Commun, 15, 2024
5IC8
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Structure of UTP6
分子名称: Putative uncharacterized protein
著者Zhang, C, Ye, K.
登録日2016-02-23
公開日2016-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Integrative structural analysis of the UTPB complex, an early assembly factor for eukaryotic small ribosomal subunits
Nucleic Acids Res., 44, 2016
2PAB
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STRUCTURE OF PREALBUMIN, SECONDARY, TERTIARY AND QUATERNARY INTERACTIONS DETERMINED BY FOURIER REFINEMENT AT 1.8 ANGSTROMS
分子名称: TRANSTHYRETIN PRECURSOR
著者Oatley, S.J, Blake, C.C.F.
登録日1977-09-16
公開日1977-10-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A.
J.Mol.Biol., 121, 1978
1HL3
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CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide
分子名称: C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE
著者Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M.
登録日2003-03-13
公開日2003-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission
Embo J., 22, 2003
3X37
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Crystal structure of the N-terminal domain of Sld7 in complex with Sld3
分子名称: GLYCEROL, Mitochondrial morphogenesis protein SLD7, ZYRO0C14696p
著者Itou, H, Araki, H, Shirakihara, Y.
登録日2015-01-16
公開日2015-08-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3.
Acta Crystallogr.,Sect.D, 71, 2015
3X38
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Crystal structure of the C-terminal domain of Sld7
分子名称: GLYCEROL, Mitochondrial morphogenesis protein SLD7, SULFATE ION
著者Itou, H, Araki, H, Shirakihara, Y.
登録日2015-01-16
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3.
Acta Crystallogr.,Sect.D, 71, 2015
8ENJ
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BU of 8enj by Molmil
Design, synthesis, biological evaluation, and X-ray crystallography of diarylpyrazole derivatives possessing terminal arylsulfonamide moieties as anti-proliferative agents targeting c-Jun N-terminal kinase (JNK)
分子名称: Mitogen-activated protein kinase 10, N-[3-({(4P)-4-[(3M)-1-tert-butyl-3-(3-hydroxyphenyl)-1H-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamide
著者Park, H, Mersal, K.I.
登録日2022-09-30
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Eur.J.Med.Chem., 261, 2023
6NPW
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SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
分子名称: PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ...
著者Irani, S, Zhang, Y.
登録日2019-01-18
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.
J.Biol.Chem., 294, 2019
8AI7
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Structure of carbamoylated human butyrylcholinesterase upon reaction with 3-(((2-cycloheptylethyl)(methyl)amino)methyl)-1H-indol-7-yl N,N-dimethylcarbamate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[[2-cycloheptylethyl(methyl)amino]methyl]-1~{H}-indol-7-ol, ...
著者Brazzolotto, X, Meden, A, Knez, D, Gobec, S, Nachon, F.
登録日2022-07-25
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead.
Eur.J.Med.Chem., 247, 2023
4Z1M
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Bovine F1-ATPase inhibited by three copies of the inhibitor protein IF1 crystallised in the presence of thiophosphate.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
著者Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2015-03-27
公開日2015-05-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献How release of phosphate from mammalian F1-ATPase generates a rotary substep.
Proc.Natl.Acad.Sci.USA, 112, 2015
6KYU
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Complex assembly, crystallization and preliminary X-ray crystallographic studies of duck MHC class I molecule
分子名称: Beta-2-microglobulin, MHC class I antigen, peptide
著者Liu, Z.X, Zhang, L, Zhang, N.Z.
登録日2019-09-20
公開日2020-09-23
最終更新日2020-12-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the duck pAnpl-UAA
To Be Published

223532

件を2024-08-07に公開中

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