6JEB
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![BU of 6jeb by Molmil](/molmil-images/mine/6jeb) | crystal structure of a beta-N-acetylhexosaminidase | 分子名称: | ACETAMIDE, Beta-N-acetylhexosaminidase, ZINC ION | 著者 | Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M. | 登録日 | 2019-02-05 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | 主引用文献 | Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila. Biochem. Biophys. Res. Commun., 511, 2019
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5WR9
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![BU of 5wr9 by Molmil](/molmil-images/mine/5wr9) | Crystal structure of hen egg-white lysozyme | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Sugahara, M, Suzuki, M, Masuda, T, Inoue, S, Nango, E. | 登録日 | 2016-12-01 | 公開日 | 2017-12-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hydroxyethyl cellulose matrix applied to serial crystallography Sci Rep, 7, 2017
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7WQM
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![BU of 7wqm by Molmil](/molmil-images/mine/7wqm) | Crystal structure of Aldo-keto reductase 1C3 complexed with compound 24 | 分子名称: | 2-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-~{N}-(2-methoxyphenyl)benzamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Jiang, J, Liu, Y, He, S, Chen, Y, Chu, X, Liu, Y, Guo, Q, Zhao, L, Feng, F, Liu, W, Zhang, X, Sun, H, Fang, P. | 登録日 | 2022-01-25 | 公開日 | 2023-01-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer. Eur.J.Med.Chem., 247, 2022
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2VFV
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![BU of 2vfv by Molmil](/molmil-images/mine/2vfv) | Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sulphite | 分子名称: | (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, CHLORIDE ION, XYLITOL OXIDASE | 著者 | Forneris, F, Mattevi, A. | 登録日 | 2007-11-05 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
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6JME
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![BU of 6jme by Molmil](/molmil-images/mine/6jme) | Crystal structure of human DHODH in complex with inhibitor 0946 | 分子名称: | 3-[3,5-bis(fluoranyl)-4-(2-fluorophenyl)phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Yu, Y, Chen, Q. | 登録日 | 2019-03-08 | 公開日 | 2020-03-18 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
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6DV2
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![BU of 6dv2 by Molmil](/molmil-images/mine/6dv2) | Crystal Structure of Human Mitochondrial Trifunctional Protein | 分子名称: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | 著者 | Fu, Z, Xia, C, Battaile, K.P, Kim, J.P. | 登録日 | 2018-06-22 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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7W4L
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![BU of 7w4l by Molmil](/molmil-images/mine/7w4l) | Deactive state CI from Q1-NADH dataset, Subclass 3 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-28 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6BNH
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![BU of 6bnh by Molmil](/molmil-images/mine/6bnh) | Solution NMR structures of BRD4 ET domain with JMJD6 peptide | 分子名称: | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4 | 著者 | Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L. | 登録日 | 2017-11-16 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4. Sci Rep, 7, 2017
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7WJK
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![BU of 7wjk by Molmil](/molmil-images/mine/7wjk) | Complex structure of AtHPPD-ZWJ | 分子名称: | 3-[2-[4-[[4-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-8-yl]phenoxy]methyl]-1,2,3-triazol-1-yl]ethyl]-1,5-dimethyl-6-[(1S)-2-oxidanyl-6-oxidanylidene-cyclohex-2-en-1-yl]carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Yang, G.-F, Lin, H.-Y, Dong, J. | 登録日 | 2022-01-06 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.704 Å) | 主引用文献 | Complex structure of AtHPPD-PyQ1 To Be Published
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6JML
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![BU of 6jml by Molmil](/molmil-images/mine/6jml) | Re-refined structure of R-state L-lactate dehydrogenase fromLactobacillus casei | 分子名称: | L-lactate dehydrogenase, SULFATE ION | 著者 | Arai, K, Miyanaga, A, Uchikoba, H, Fushinobu, S, Taguchi, H. | 登録日 | 2019-03-12 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of penta mutant of L-lactate dehydrogenase from Lactobacillus casei To Be Published
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7W1Z
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![BU of 7w1z by Molmil](/molmil-images/mine/7w1z) | Active state CI from Rotenone-NADH dataset, Subclass 2 | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-21 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6JGA
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![BU of 6jga by Molmil](/molmil-images/mine/6jga) | Crystal structure of barley exohydrolaseI W286F in complex with 4'-nitrophenyl thiolaminaribioside | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-4-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-oxane-2,3,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ... | 著者 | Luang, S, Streltsov, V.A, Hrmova, M. | 登録日 | 2019-02-13 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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5WUG
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![BU of 5wug by Molmil](/molmil-images/mine/5wug) | Expression, characterization and crystal structure of a novel beta-glucosidase from Paenibacillus barengoltzii | 分子名称: | Beta-glucosidase | 著者 | Jiang, Z, Wu, S, Yang, D, Qin, Z, You, X, Huang, P. | 登録日 | 2016-12-17 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.216 Å) | 主引用文献 | Expression, Biochemical Characterization and Structure Resolution of beta-glucosidase from Paenibacillus barengoltzii J Food Sci Technol(China), 2019
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3HMZ
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![BU of 3hmz by Molmil](/molmil-images/mine/3hmz) | |
6JGL
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![BU of 6jgl by Molmil](/molmil-images/mine/6jgl) | Crystal structure of barley exohydrolaseI W434H mutant in complex with methyl 2-thio-beta-sophoroside | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ... | 著者 | Luang, S, Streltsov, V.A, Hrmova, M. | 登録日 | 2019-02-14 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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3DYP
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![BU of 3dyp by Molmil](/molmil-images/mine/3dyp) | E. coli (lacZ) beta-galactosidase (H418N) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | 登録日 | 2008-07-28 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli). Protein Sci., 18, 2009
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2VKU
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![BU of 2vku by Molmil](/molmil-images/mine/2vku) | 4,4'-Dihydroxybenzophenone Mimics Sterol Substrate in the Binding Site of Sterol 14alpha-Demethylase (CYP51) in the X-ray Structure of the Complex | 分子名称: | CYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | 著者 | Eddine, A.N, von Kries, J.P, Podust, M.V, Podust, L.M. | 登録日 | 2007-12-29 | 公開日 | 2008-03-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | X-Ray Structure of 4,4'-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14Alpha-Demethylase (Cyp51) J.Biol.Chem., 283, 2008
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7P9X
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![BU of 7p9x by Molmil](/molmil-images/mine/7p9x) | Structure of cyclohex-1-ene-1-carboxyl-CoA dehydrogenase complexed with cyclohex-1-ene-1-carboxyl-CoA | 分子名称: | 1-monoenoyl-CoA, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Ermler, U, Weidenweber, S, Boll, M. | 登録日 | 2021-07-28 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Basis of Cyclic 1,3-Diene Forming Acyl-Coenzyme A Dehydrogenases. Chembiochem, 22, 2021
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3DBV
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![BU of 3dbv by Molmil](/molmil-images/mine/3dbv) | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH LEU 33 REPLACED BY THR, THR 34 REPLACED BY GLY, ASP 36 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NAD+ | 分子名称: | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | 著者 | Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A. | 登録日 | 1997-01-06 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+. J.Mol.Biol., 268, 1997
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4PRW
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![BU of 4prw by Molmil](/molmil-images/mine/4prw) | Xylanase T6 (XT6) from Geobacillus Stearothermophilus in complex with xylohexaose | 分子名称: | CHLORIDE ION, Endo-1,4-beta-xylanase, SULFATE ION, ... | 著者 | Dann, R.D, Solomon, H.V, Lansky, S, Ben-David, A, Lavid, N, Salama, R, Shoham, Y, Shoham, G. | 登録日 | 2014-03-06 | 公開日 | 2015-03-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Xylanase T6 (XT6) from Geobacillus Stearothermophilus in complex with xylohexaose To be Published
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2V8D
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![BU of 2v8d by Molmil](/molmil-images/mine/2v8d) | Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri | 分子名称: | BETA-ALANINE SYNTHASE, ZINC ION | 著者 | Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D. | 登録日 | 2007-08-07 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements. J.Biol.Chem., 282, 2007
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7W4G
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![BU of 7w4g by Molmil](/molmil-images/mine/7w4g) | Active state CI from Q1-NADH dataset, Subclass 5 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-27 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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5W78
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![BU of 5w78 by Molmil](/molmil-images/mine/5w78) | Human acyloxyacyl hydrolase (AOAH), proteolytically processed | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, CALCIUM ION, ... | 著者 | Gorelik, A, Illes, K, Nagar, B. | 登録日 | 2017-06-19 | 公開日 | 2018-01-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.271 Å) | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6JKU
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![BU of 6jku by Molmil](/molmil-images/mine/6jku) | Crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-acetylglucosamine-6-phosphate deacetylase, ... | 著者 | Manjunath, L, Bose, S, Subramanian, R. | 登録日 | 2019-03-01 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Quaternary variations in the structural assembly of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella multocida. Proteins, 2020
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4PJ0
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![BU of 4pj0 by Molmil](/molmil-images/mine/4pj0) | Structure of T.elongatus Photosystem II, rows of dimers crystal packing | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Hellmich, J, Bommer, M, Burkhardt, A, Ibrahim, M, Kern, J, Meents, A, Mueh, F, Dobbek, H, Zouni, A. | 登録日 | 2014-05-10 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.437 Å) | 主引用文献 | Native-like Photosystem II Superstructure at 2.44 angstrom Resolution through Detergent Extraction from the Protein Crystal. Structure, 22, 2014
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