PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

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7TBN	LOV2-DARPIN fusion : D11 分子名称: CARBONATE ION, D11 LOV2-DARPin fusion, GLYCEROL 著者 Mittl, P. 登録日 2021-12-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 LOV2-DARPIN fusion : D11 To Be Published
7TBO	LOV2-DARPIN fusion : D12 分子名称: D12 LOV2-DARPin fusion, GLYCEROL 著者 Mittl, P. 登録日 2021-12-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 LOV2-DARPIN fusion : D12 To Be Published
7TCD	LOV2-DARPIN fusion: D13 分子名称: CHLORIDE ION, D13 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ... 著者 Mittl, P. 登録日 2021-12-23 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 LOV2-DARPIN fusion: D13 To Be Published
7TBQ	LOV2-DARPIN fusion : D7 分子名称: CHLORIDE ION, D7 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ... 著者 Mittl, P. 登録日 2021-12-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.678 Å) 主引用文献 LOV2-DARPIN fusion : D7 To Be Published
1T6W	RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES 分子名称: CALCIUM ION, hypothetical protein XP_346638 著者 Yang, W, Wilkins, A.L, Ye, Y, Liu, Z.-R, Urbauer, J.L, Kearney, A, van der Merwe, P.A, Yang, J.J. 登録日 2004-05-07 公開日 2005-02-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Design of a calcium-binding protein with desired structure in a cell adhesion molecule. J.Am.Chem.Soc., 127, 2005
1STO	CRYSTAL STRUCTURE OF OROTATE PHOSPHORIBOSYLTRANSFERASE 分子名称: HYDROXIDE ION, OROTATE PHOSPHORIBOSYLTRANSFERASE, OROTIDINE-5'-MONOPHOSPHATE 著者 Scapin, G, Grubmeyer, C, Sacchettini, J.C. 登録日 1993-12-20 公開日 1994-05-31 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of orotate phosphoribosyltransferase. Biochemistry, 33, 1994
1TJB	Crystal Structure of a High Affinity Lanthanide-Binding Peptide (LBT) 分子名称: CHLORIDE ION, Lanthanide-Binding Peptide, TERBIUM(III) ION 著者 Nitz, M, Sherawat, M, Franz, K.J, Peisach, E, Allen, K.N, Imperiali, B. 登録日 2004-06-03 公開日 2004-08-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Origin of the High Affinity of a Chemically Evolved Lanthanide-Binding Peptide Angew.Chem.Int.Ed.Engl., 43, 2004
6Q1W	Coiled-coil Trimer with Glu:Val:Lys Triad 分子名称: Coiled-coil Trimer with Glu:Val:Lys Triad 著者 Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. 登録日 2019-08-06 公開日 2020-04-29 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (1.498 Å) 主引用文献 Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
7Q3J	Computationally designed thioredoxin subjected to stability optimizing mutations. 分子名称: GLYCEROL, MM9 著者 Norrild, R.K, Johansson, K.E, O'Shea, C, Lindorff-Larsen, K, Winther, J.R, Morth, J.P. 登録日 2021-10-27 公開日 2022-11-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Increasing protein stability by inferring substitution effects from high-throughput experiments. Cell Rep Methods, 2, 2022
3E78	Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37 分子名称: CALCIUM ION, CHLORIDE ION, High affinity transport system protein p37, ... 著者 Sippel, K.H, Robbins, A.H, Reutzel, R, Domsic, J, McKenna, R. 登録日 2008-08-18 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallogr.,Sect.D, 64, 2008
7AX0	Crystal structure of the computationally designed Scone-E protein co-crystallized with STA form a 分子名称: Keggin (STA), PHOSPHATE ION, SconeE 著者 Mylemans, B, Vandebroek, L, Parac-Vogt, T.N, Voet, A.R.D. 登録日 2020-11-09 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of Scone: pseudosymmetric folding of a symmetric designer protein. Acta Crystallogr D Struct Biol, 77, 2021
7B4T	Broadly neutralizing DARPin bnD.1 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) 分子名称: Broadly neutralizing DARPin bnD.1, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), SULFATE ION 著者 Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A. 登録日 2020-12-02 公開日 2021-11-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12, 2021
7B4U	Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) 分子名称: Broadly neutralizing DARPin bnD.2, CALCIUM ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) 著者 Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A. 登録日 2020-12-02 公開日 2021-11-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12, 2021
5K5M	Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ... 著者 Arora, R, Benson, T.E. 登録日 2016-05-23 公開日 2016-08-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling. Plos Pathog., 12, 2016
5KKG	Crystal structure of E72A mutant of ancestral protein ancMT of ADP-dependent sugar kinases family 分子名称: ADENOSINE MONOPHOSPHATE, GLYCEROL, IODIDE ION, ... 著者 Castro-Fernandez, V, Herrera-Morande, A, Zamora, R, Merino, F, Pereira, H.M, Brandao-Neto, J, Garratt, R, Guixe, V. 登録日 2016-06-21 公開日 2017-07-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.608 Å) 主引用文献 Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. J. Biol. Chem., 292, 2017
5VF1	X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic Beta-Sheet Containing ABeta16-22 分子名称: ORN-LYS-LEU-VAL-PHI-PHE-ALA-GLU-ORN-GLU-ALA-PHE-MEA-VAL-LEU-LYS 著者 Chen, K.H, Corro, K.A, Le, S.P, Nowick, J.S. 登録日 2017-04-06 公開日 2017-06-21 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic beta-Sheet Containing A beta 16-22. J. Am. Chem. Soc., 139, 2017
8V3B	Computational Designed Nanocage O43_129_+4 分子名称: O43_129_+4 component A, O43_129_+4 component B 著者 Carr, K.D, Weidle, C, Borst, A.J. 登録日 2023-11-27 公開日 2024-03-13 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Blueprinting extendable nanomaterials with standardized protein blocks. Nature, 627, 2024
6O3N	Cross-alpha Amyloid-like Structure alphaAmA 分子名称: Cross-alpha Amyloid-like Structure alphaAmA 著者 Zhang, S.-Q, Liu, L, DeGrado, W.F. 登録日 2019-02-26 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Designed peptides that assemble into cross-alpha amyloid-like structures Nat. Chem. Biol., 14, 2018
6OWD	Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly 分子名称: CHLORIDE ION, R+7 著者 Biok, N.A, Bingman, C.A, Gellman, S.H. 登録日 2019-05-09 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. Biochemistry, 58, 2019
8A1A	Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... 著者 Mittl, P.R.E. 登録日 2022-06-01 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
8A19	Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... 著者 Mittl, P.R.E. 登録日 2022-06-01 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.358 Å) 主引用文献 Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
7ZI1	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the dCKi1 inhibitor 分子名称: Deoxycytidine kinase, N-[3-[[4-(4-azanylpyrimidin-2-yl)-1,3-thiazol-2-yl]amino]-4-methyl-phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide, SODIUM ION, ... 著者 Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. 登録日 2022-04-07 公開日 2023-06-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI9	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0624 inhibitor 分子名称: 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine, Deoxycytidine kinase, SODIUM ION, ... 著者 Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. 登録日 2022-04-07 公開日 2023-06-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI3	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0642 inhibitor 分子名称: 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonyl-2-(trifluoromethyl)phenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine, Deoxycytidine kinase, SODIUM ION, ... 著者 Ben-Yaala, K, Saez-Ayala, M, Betzi, S, Rebuffet, E, Morelli, X. 登録日 2022-04-07 公開日 2023-06-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI6	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0325 inhibitor 分子名称: 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl]phenyl]-1,3-thiazol-2-amine, Deoxycytidine kinase, SODIUM ION, ... 著者 Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. 登録日 2022-04-07 公開日 2023-06-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023

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