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4O7R
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SAICAR synthetase (Type-2) in complex with UMP/UDP
分子名称: ACETATE ION, PHOSPHATE ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ...
著者Manjunath, K, Jeyakanthan, J, Sekar, K.
登録日2013-12-26
公開日2014-12-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献SAICAR synthetase (Type-2) in complex with UMP/UDP
To be Published
4O84
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BU of 4o84 by Molmil
SAICAR synthetase (Type-1) in complex with GMP
分子名称: 1,4-BUTANEDIOL, CADMIUM ION, GUANOSINE-5'-MONOPHOSPHATE, ...
著者Manjunath, K, Jeyakanthan, J, Sekar, K.
登録日2013-12-26
公開日2014-12-31
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献SAICAR synthetase (Type-1) in complex with GMP
To be Published
4FGR
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BU of 4fgr by Molmil
X-Ray Structure of SAICAR Synthetase (PurC) from Streptococcus pneumoniae complexed with ADP and Mg2+
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Fung, L.W.-M, Johnson, M.E, Abad-Zapatero, C, Wolf, N.W.
登録日2012-06-04
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献

4EHI
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BU of 4ehi by Molmil
An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional purine biosynthesis protein PurH, SULFATE ION
著者Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Kwok, J, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-04-02
公開日2012-06-06
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase
TO BE PUBLISHED
2NSJ
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BU of 2nsj by Molmil
E. coli PurE H45Q mutant complexed with CAIR
分子名称: 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
4HVR
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BU of 4hvr by Molmil
X-ray crystal structure of salicylic acid bound 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
分子名称: 2-HYDROXYBENZOIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, FE (III) ION
著者Liu, F, Chen, L, Liu, A.
登録日2012-11-06
公開日2013-11-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray crystal structure of salicylic acid bound 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
To be Published
4R3N
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BU of 4r3n by Molmil
Crystal structure of the ternary complex of sp-ASADH with NADP and 1,2,3-Benzenetricarboxylic acid
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2014-08-16
公開日2014-12-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4QQU
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BU of 4qqu by Molmil
Crystal structure of the cobalamin-independent methionine synthase enzyme in a closed conformation
分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, N-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acid, ...
著者Ubhi, D.K, Robertus, J.D.
登録日2014-06-29
公開日2015-01-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献The cobalamin-independent methionine synthase enzyme captured in a substrate-induced closed conformation.
J.Mol.Biol., 427, 2015
4HVO
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BU of 4hvo by Molmil
1.75 angstrom x-ray crystal structure of cufe reconstituted 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, COPPER (II) ION, FE (II) ION
著者Liu, F, Chen, L, Liu, A.
登録日2012-11-06
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE.
J.Biol.Chem., 290, 2015
4R7G
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BU of 4r7g by Molmil
Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ...
著者Tanwar, A.S, Sindhikara, D.J, Hirata, F, Anand, R.
登録日2014-08-27
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment.
Acs Chem.Biol., 10, 2015
2NSL
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BU of 2nsl by Molmil
E. coli PurE H45N mutant complexed with CAIR
分子名称: 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
4R52
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BU of 4r52 by Molmil
1.5 angstrom crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION
著者Geng, J, Gumpper, R.H, Huo, L, Liu, A.
登録日2014-08-20
公開日2016-03-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献1.5 angstrom crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans
To be Published
4HSJ
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BU of 4hsj by Molmil
1.88 angstrom x-ray crystal structure of piconlinic-bound 3-hydroxyanthranilate-3,4-dioxygenase
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION, PYRIDINE-2-CARBOXYLIC ACID
著者Liu, F, Chen, L, Davis, C.I, Liu, A.
登録日2012-10-30
公開日2015-05-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.883 Å)
主引用文献An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE.
J.Biol.Chem., 290, 2015
2NSH
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BU of 2nsh by Molmil
E. coli PurE H45Q mutant complexed with nitro-AIR
分子名称: ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
4I3P
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BU of 4i3p by Molmil
1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase bound with 3-aminosalicylic acid from cupriavidus metallidurans
分子名称: 3-amino-2-hydroxybenzoic acid, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION
著者Liu, F, Liu, A.
登録日2012-11-26
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.961 Å)
主引用文献1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase bound with 3-aminosalicylic acid from cupraavidus metallidurans
TO BE PUBLISHED
4HSL
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BU of 4hsl by Molmil
2.00 angstrom x-ray crystal structure of substrate-bound E110A 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans
分子名称: 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION
著者Liu, F, Chen, L, Liu, A.
登録日2012-10-30
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2.00 angstrom x-ray crystal structure of substrate-bound E110A 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans
To be Published
2ND5
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BU of 2nd5 by Molmil
Lysine dimethylated FKBP12
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A
著者Hattori, Y, Sebera, J, Sychrovsky, V, Furuita, K, Sugiki, T, Ohki, I, Ikegami, T, Kobayashi, N, Tanaka, Y, Fujiwara, T, Kojima, C.
登録日2016-05-05
公開日2017-05-17
実験手法SOLUTION NMR
主引用文献NMR Observation of Protein Surface Salt Bridges at Neutral pH
To be Published
3NRB
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BU of 3nrb by Molmil
Crystal structure of a formyltetrahydrofolate deformylase (purU, PP_1943) from PSEUDOMONAS PUTIDA KT2440 at 2.05 A resolution
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Formyltetrahydrofolate deformylase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-06-30
公開日2010-07-28
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a formyltetrahydrofolate deformylase (purU, PP_1943) from PSEUDOMONAS PUTIDA KT2440 at 2.05 A resolution
To be published
3NWY
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BU of 3nwy by Molmil
Structure and allosteric regulation of the uridine monophosphate kinase from Mycobacterium tuberculosis
分子名称: GUANOSINE-5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE, Uridylate kinase
著者Labesse, G, Munier-Lehmann, H.
登録日2010-07-12
公開日2010-08-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.
Nucleic Acids Res., 39, 2011
3NUA
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BU of 3nua by Molmil
Crystal Structure of Phosphoribosylaminoimidazole-Succinocarboxamide Synthase from Clostridium perfringens
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, ...
著者Kim, Y, Mulligan, R, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-07-06
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of Phosphoribosylaminoimidazole-Succinocarboxamide Synthase from Clostridium perfringens
To be Published
3P9X
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BU of 3p9x by Molmil
Crystal structure of phosphoribosylglycinamide formyltransferase from Bacillus Halodurans
分子名称: GLYCEROL, SULFATE ION, phosphoribosylglycinamide formyltransferase
著者Patskovsky, Y, Toro, R, Foti, R, Seidel, R.D, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2010-10-18
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of phosphoribosylglycinamide formyltransferase from Bacillus Halodurans
To be Published
3OPQ
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BU of 3opq by Molmil
Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure.
分子名称: CHLORIDE ION, FORMIC ACID, FRUCTOSE -6-PHOSPHATE, ...
著者Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-09-01
公開日2010-11-17
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure.
To be Published
3OOW
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BU of 3oow by Molmil
Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FORMIC ACID, ...
著者Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, F.W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-08-31
公開日2010-09-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4.
To be Published
3PPF
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BU of 3ppf by Molmil
Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant without zinc
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
著者Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
登録日2010-11-24
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
3PPC
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Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, tyrosine variant with zinc
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, CHLORIDE ION, ZINC ION
著者Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
登録日2010-11-24
公開日2011-10-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011

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件を2024-08-28に公開中

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