PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4TS3	Wild type E. Coli purine nucleoside phosphorylase with 2 FMC molecules in active sites 分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Stefanic, Z, Bzowska, A. 登録日 2014-06-18 公開日 2015-07-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
3TK8	Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei 分子名称: 1,2-ETHANEDIOL, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, SULFATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-08-25 公開日 2011-10-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei TO BE PUBLISHED
2GWS	Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus 分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', ... 著者 Garcia-Diaz, M, Picher, A.J, Bebenek, K, Pedersen, L.C, Kunkel, T.A, Blanco, L. 登録日 2006-05-05 公開日 2006-09-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Res., 34, 2006
2ZZJ	Crystal structure of endo-beta-1,4-glucuronan lyase from fungus Trichoderma reesei 分子名称: CALCIUM ION, CITRIC ACID, Glucuronan lyase A 著者 Konno, N, Ishida, T, Fushinobu, S, Igarashi, K, Habu, N, Samejima, M, Isogai, A. 登録日 2009-02-16 公開日 2009-05-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of polysaccharide lyase family 20 endo-beta-1,4-glucuronan lyase from the filamentous fungus Trichoderma reesei. Febs Lett., 583, 2009
4JBO	Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules 分子名称: 1-(4-{2-[(6-{4-[2-(dimethylamino)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea, Aurora kinase A 著者 Wu, J.S, Leou, J.S, Peng, Y.H, Hsueh, C.C, Hsieh, H.P, Wu, S.Y. 登録日 2013-02-20 公開日 2013-06-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.493 Å) 主引用文献 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc.Natl.Acad.Sci.USA, 110, 2013
4MRF	Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule 分子名称: 1,2,3,4-tetrahydroisoquinoline, CD44 antigen, DIMETHYL SULFOXIDE, ... 著者 Liu, L.K, Finzel, B. 登録日 2013-09-17 公開日 2014-04-16 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein-Carbohydrate Interaction Inhibitors. J.Med.Chem., 57, 2014
1HOR	STRUCTURE AND CATALYTIC MECHANISM OF GLUCOSAMINE 6-PHOSPHATE DEAMINASE FROM ESCHERICHIA COLI AT 2.1 ANGSTROMS RESOLUTION 分子名称: 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, GLUCOSAMINE 6-PHOSPHATE DEAMINASE, PHOSPHATE ION 著者 Oliva, G, Fontes, M.R.M, Garratt, R.C, Altamirano, M.M, Calcagno, M.L, Horjales, E. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution. Structure, 3, 1995
2HBP	Solution Structure of Sla1 Homology Domain 1 分子名称: Cytoskeleton assembly control protein SLA1 著者 Overduin, M, Mahadev, R.K. 登録日 2006-06-14 公開日 2007-04-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of Sla1p homology domain 1 and interaction with the NPFxD endocytic internalization motif. Embo J., 26, 2007
3A4N	Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase 分子名称: 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ... 著者 Araiso, Y, Ishitani, R, Soll, D, Nureki, O. 登録日 2009-07-10 公開日 2009-10-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a tRNA-dependent kinase essential for selenocysteine decoding Proc.Natl.Acad.Sci.USA, 106, 2009
3WY9	Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha 分子名称: 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE 著者 Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. 登録日 2014-08-22 公開日 2014-12-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
3OQ8	Crystal structure of isocitrate lyase from Brucella melitensis, bound to the product mimic malonate 分子名称: 1,2-ETHANEDIOL, Isocitrate lyase, MALONIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-09-02 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of isocitrate lyase from Brucella melitensis, bound to the product mimic malonate To be Published
2EKJ	Solution structures of the fn3 domain of human collagen alpha-1(XX) chain 分子名称: Collagen alpha-1(XX) chain 著者 Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-23 公開日 2007-09-25 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structures of the fn3 domain of human collagen alpha-1(XX) chain To be Published
2QIM	Crystal Structure of Pathogenesis-related Protein LlPR-10.2B from yellow lupine in complex with Cytokinin 分子名称: (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, CALCIUM ION, GLYCEROL, ... 著者 Fernandes, H.C, Pasternak, O, Bujacz, G, Bujacz, A, Sikorski, M.M, Jaskolski, M. 登録日 2007-07-05 公開日 2008-04-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Lupinus luteus pathogenesis-related protein as a reservoir for cytokinin. J.Mol.Biol., 378, 2008
2HB4	Structure of HIV Protease NL4-3 in an Unliganded State 分子名称: MAGNESIUM ION, Protease, R-1,2-PROPANEDIOL 著者 Heaslet, H, Tam, K, Elder, J.H, Stout, C.D. 登録日 2006-06-13 公開日 2007-06-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63, 2007
4PO9	Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BR 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ... 著者 Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M. 登録日 2014-02-25 公開日 2015-03-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability J.Biosci., 40, 2015
4JVR	Co-crystal structure of MDM2 with inhibitor (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide 分子名称: (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2 著者 Huang, X, Gonzalez-Lopez de Turiso, F, Sun, D, Yosup, R, Bartberger, M.D, Beck, H.P, Cannon, J, Shaffer, P, Oliner, J.D, Olson, S.H, Medina, J.C. 登録日 2013-03-26 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors. J.Med.Chem., 56, 2013
2GCN	Crystal structure of the human RhoC-GDP complex 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Dias, S.M.G, Cerione, R.A. 登録日 2006-03-14 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray Crystal Structures Reveal Two Activated States for RhoC. Biochemistry, 46, 2007
397D	A 1.3 A RESOLUTION CRYSTAL STRUCTURE OF THE HIV-1 TRANS-ACTIVATION RESPONSE REGION RNA STEM REVEALS A METAL ION-DEPENDENT BULGE CONFORMATION 分子名称: CALCIUM ION, RNA (5'-R(*GP*CP*UP*CP*UP*CP*UP*GP*GP*CP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3') 著者 Ippolito, J.A, Steitz, T.A. 登録日 1998-04-30 公開日 1998-09-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation. Proc.Natl.Acad.Sci.USA, 95, 1998
7L35	Human DNA Ligase 1 - R771W nicked DNA complex 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Tumbale, P.P, Williams, R.S, Schellenberg, M.S. 登録日 2020-12-17 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency. Nucleic Acids Res., 49, 2021
2EEJ	Solution Structure of Fourth PDZ domain of PDZ Domain Containing Protein 1 分子名称: PDZ domain-containing protein 1 著者 Niraula, T.N, Tomizawa, T, Koshiba, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-15 公開日 2008-02-26 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Fourth PDZ domain of PDZ Domain Containing Protein 1 To be Published
3A4L	Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase 分子名称: 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ... 著者 Araiso, Y, Ishitani, R, Soll, D, Nureki, O. 登録日 2009-07-10 公開日 2009-10-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a tRNA-dependent kinase essential for selenocysteine decoding Proc.Natl.Acad.Sci.USA, 106, 2009
3OV6	CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) 分子名称: 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... 著者 Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. 登録日 2010-09-15 公開日 2011-01-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation Immunity, 33, 2010
1GIQ	Crystal Structure of the Enzymatic Componet of Iota-Toxin from Clostridium Perfringens with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, IOTA TOXIN COMPONENT IA 著者 Tsuge, H, Nagahama, M, Nishimura, H, Hisatsune, J, Sakaguchi, Y, Itogawa, Y, Katunuma, N, Sakurai, J. 登録日 2001-03-12 公開日 2003-01-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin J.MOL.BIOL., 325, 2003
7KVM	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-{[(2R)-2-benzyl-3-oxo-3-{[3-(pyridin-3-yl)propyl]amino}propyl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I. 登録日 2020-11-28 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Rational Design of CYP3A4 Inhibitors: A One-Atom Linker Elongation in Ritonavir-Like Compounds Leads to a Marked Improvement in the Binding Strength. Int J Mol Sci, 22, 2021
4FLF	Structure of three phase partition treated lipase from Thermomyces lanuginosa at 2.15A resolution. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrobenzaldehyde, ... 著者 Kumar, M, Mukherjee, J, Sinha, M, Kaur, P, Gupta, M.N, Sharma, S, Singh, T.P. 登録日 2012-06-14 公開日 2012-07-11 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa Sustain Chem Process, 2015

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