PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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3H3V	Yeast RNAP II containing poly(A)-signal sequence in the active site 分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... 著者 Dengl, S, Cramer, P. 登録日 2009-04-17 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
3J1N	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
8OEW	Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
1A1D	YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY 分子名称: RNA POLYMERASE 著者 Krapp, S, Kelly, G, Reischl, J, Weinzierl, R, Matthews, S. 登録日 1997-12-10 公開日 1999-03-02 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family. Nat.Struct.Biol., 5, 1998
8PNQ	Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PNP	Influenza A/H7N9 polymerase in pre-initiation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PM0	Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-27 公開日 2024-02-21 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3L	Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3K	Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide mimic bound in site 1A/2A. 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8POH	Influenza A/H7N9 polymerase symmetric dimer bound to the promoter (PA K289A/C489R) 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-04 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
6XI8	Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... 著者 van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. 登録日 2020-06-19 公開日 2021-04-28 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
8T1I	Atomic model of the mammalian Mediator complex with MED26 subunit 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-02 公開日 2024-06-12 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.68 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
8T1L	Atomic model of the mammalian mouse Mediator complex with CKM module 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-02 公開日 2024-07-03 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (4.83 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
8T9D	CryoEM structure of TR-TRAP 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-23 公開日 2024-07-03 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (4.66 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
7KUE	CryoEM structure of Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... 著者 van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. 登録日 2020-11-24 公開日 2021-04-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
3FMV	Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. 分子名称: Serine phosphatase of RNA polymerase II CTD 著者 Kuzin, A.P, Chen, Y, Seetharaman, J, Forouhar, F, Chinag, Y, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2008-12-22 公開日 2009-01-06 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. To be Published
4JXT	CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD 分子名称: DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION 著者 Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) 登録日 2013-03-28 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
4YGY	Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide 分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide 著者 Mayfield, J.E, Zhang, Y. 登録日 2015-02-26 公開日 2015-09-16 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
4YH1	Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide 分子名称: A small phosphatase 1, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION 著者 Mayfield, J.E, Zhang, Y. 登録日 2015-02-26 公開日 2015-09-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
6DT8	Bacteriophage N4 RNA polymerase II elongation complex 1 分子名称: DNA (5'-D(P*AP*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*UP*GP*G)-3'), RNAP1, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-06-15 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
6DTA	Bacteriophage N4 RNA polymerase II elongation complex 2 分子名称: DNA (5'-D(P*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-06-15 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.694 Å) 主引用文献 Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
3J1O	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
4IMJ	Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72 分子名称: CG14216, CTD, PHOSPHATE ION, ... 著者 Luo, Y, Yogesha, S.D, Zhang, Y. 登録日 2013-01-03 公開日 2013-08-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72. Acs Chem.Biol., 8, 2013
4PN0	Structure of S. pombe Pct1 RNA triphosphatase 分子名称: mRNA-capping enzyme subunit beta 著者 Lima, C.D, Doamekpor, S.K. 登録日 2014-05-22 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Fission yeast RNA triphosphatase reads an Spt5 CTD code. Rna, 21, 2015
6DT7	Bacteriophage N4 RNA polymerase II and DNA complex 分子名称: DNA (5'-D(P*CP*CP*AP*CP*CP*TP*GP*CP*A)-3'), RNAP1, RNAP2 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-06-15 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018

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