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3QFD
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Human Class I MHC HLA-A2 in complex with Mart-1(27-35) nonameric peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2011-01-21
公開日2011-09-28
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN.
J.Biol.Chem., 286, 2011
5T6X
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BU of 5t6x by Molmil
HLA-B*57:01 presenting TSTTSVASSW
分子名称: Beta-2-microglobulin, Decapeptide: THR-SER-THR-THR-SER-VAL-ALA-SER-SER-TRP, GLYCEROL, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.686 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
5WKE
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BU of 5wke by Molmil
Crystal Structure of Human CD1b in Complex with PS
分子名称: (19S,22S,25R)-25-amino-22-hydroxy-16,22,26-trioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shahine, A, Gras, S, Rossjohn, J.
登録日2017-07-25
公開日2017-11-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献A molecular basis of human T cell receptor autoreactivity toward self-phospholipids.
Sci Immunol, 2, 2017
7MJA
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BU of 7mja by Molmil
HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
6Y28
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BU of 6y28 by Molmil
Crystal structure of HLA-B2705 complexed with the nona-peptide mE
分子名称: Beta-2-microglobulin, GLY-ARG-LEU-ASN-GLU-PRO-ILE-LYS-VAL, GLYCEROL, ...
著者Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A.
登録日2020-02-15
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献A CENTRAL PEPTIDE RESIDUE CAN CONTROL MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION
to be published
6MY4
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BU of 6my4 by Molmil
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR]
分子名称: 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain
著者Shi, R, Picard, M.-E, Manenda, M.
登録日2018-11-01
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
6LB2
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BU of 6lb2 by Molmil
Crystal structure of rhesus macaque MHC class I molecule Mamu-B*098 complexed with mono-acyl glycerol
分子名称: (2R)-2,3-dihydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ...
著者Shima, Y, Morita, D.
登録日2019-11-13
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.69380951 Å)
主引用文献Crystal structures of lysophospholipid-bound MHC class I molecules.
J.Biol.Chem., 295, 2020
5XOS
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BU of 5xos by Molmil
Crystal structure of HLA-B35 in complex with a pepetide antigen
分子名称: An HIV reverse transcriptase epitope, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Shi, Y, Qi, J, Gao, G.F.
登録日2017-05-31
公開日2017-06-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
3V52
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BU of 3v52 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ...
著者Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H.
登録日2011-12-15
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
5TXS
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BU of 5txs by Molmil
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ...
著者Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
登録日2016-11-17
公開日2017-11-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
3ECB
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BU of 3ecb by Molmil
Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human immunodeficiency virus envelope glycoprotein 120
分子名称: 1,2-ETHANEDIOL, Beta-2 microglobulin, H-2 class I histocompatibility antigen, ...
著者Natarajan, K, Wang, R, Margulies, D.H.
登録日2008-08-29
公開日2009-07-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
J.Immunol., 183, 2009
4RMS
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BU of 4rms by Molmil
Crystal structure of the D53N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
3GMP
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BU of 3gmp by Molmil
Structure of mouse CD1d in complex with PBS-25
分子名称: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
4MDJ
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BU of 4mdj by Molmil
Immune Receptor
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scally, S.W, Rossjohn, J.
登録日2013-08-22
公開日2013-12-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis.
J.Exp.Med., 210, 2013
3GML
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BU of 3gml by Molmil
Structure of mouse CD1d in complex with C6Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMN
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BU of 3gmn by Molmil
Structure of mouse CD1d in complex with C10Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
2GTZ
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BU of 2gtz by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-28
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
6APC
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BU of 6apc by Molmil
Crystal Structure of Infant Antibody ADI-19425
分子名称: Epididymis luminal protein 214, IGL@ protein, SULFATE ION
著者Gilman, M.S.A, McLellan, J.S.
登録日2017-08-17
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
6ARP
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BU of 6arp by Molmil
Structure of a mutant Cetuximab Fab fragment
分子名称: Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Cetuximab mutant light chain,Uncharacterized protein, GLYCEROL, ...
著者Christie, M, Christ, D.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a mutant Cetuximab Fab fragment
To Be Published
2AJS
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BU of 2ajs by Molmil
Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ...
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2GIT
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BU of 2git by Molmil
Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
分子名称: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-03-29
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
2NW3
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BU of 2nw3 by Molmil
Crystal structure of HLA-B*3508 presenting EBV peptide EPLPQGQLTAY at 1.7A
分子名称: Beta-2-microglobulin, EBV peptide EPLPQGQLTAY, HLA class I histocompatibility antigen, ...
著者Tynan, F.E, Reid, H.H, Rossjohn, J.
登録日2006-11-14
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
5E00
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BU of 5e00 by Molmil
Structure of HLA-A2 P130
分子名称: Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ...
著者Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
登録日2015-09-26
公開日2017-01-18
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
3O3D
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BU of 3o3d by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
5EO0
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BU of 5eo0 by Molmil
Crystal Structure of HLA-B0702-RFL9
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Josephs, T.M, Gras, S, Rossjohn, J.
登録日2015-11-10
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016

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