PDB: 317 件ウェブページステータス検索Chemie searchBIRD

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7SZJ	Cryo-EM structure of Rifamycin bound to E. coli RNAP and rrnBP1 promoter complex 分子名称: DNA (49-MER), DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2021-11-28 公開日 2022-07-13 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infect Dis., 8, 2022
7W5Y	Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y. 登録日 2021-11-30 公開日 2022-10-26 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5X	Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-11-30 公開日 2022-10-26 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5W	Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y. 登録日 2021-11-30 公開日 2022-10-26 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7U22	Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 分子名称: (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Molodtsov, V, Ebright, R.H. 登録日 2022-02-22 公開日 2022-10-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.87 Å) 主引用文献 Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022
7X76	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X74	Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers. 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X75	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7UBM	Transcription antitermination complex: "pre-engaged" Qlambda-loading complex 分子名称: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ... 著者 Yin, Z, Ebright, R.H. 登録日 2022-03-15 公開日 2022-09-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7UBN	Transcription antitermination complex: NusA-containing "engaged" Qlambda-loading complex 分子名称: Antitermination protein, DNA (52-MER), DNA (53-MER), ... 著者 Yin, Z, Ebright, R.H. 登録日 2022-03-15 公開日 2022-09-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZF2	Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. 登録日 2022-03-31 公開日 2023-02-08 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
7XL4	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2022-04-21 公開日 2022-07-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XL3	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2022-04-21 公開日 2022-07-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XUI	Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Hwang, S, Kang, J.Y. 登録日 2022-05-18 公開日 2022-08-10 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
8CWR	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group R3 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... 著者 Wan, T, Zhang, L. 登録日 2022-05-19 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
8CWT	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group P43212 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... 著者 Wan, T, Zhang, L. 登録日 2022-05-19 公開日 2023-05-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
8CYF	WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA 分子名称: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), ... 著者 Wan, T, Zhang, L.M. 登録日 2022-05-23 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
7XYA	The cryo-EM structure of an AlpA-loading complex 分子名称: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wen, A, Feng, Y. 登録日 2022-06-01 公開日 2022-07-20 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
8D5V	WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera 分子名称: IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB6, RNA polymerase sigma factor SigA,DNA-directed RNA polymerase subunit beta 著者 Wan, T, Zhang, L.M. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of WhiB6 and SigA4-betaTip complex To Be Published
7YE1	The cryo-EM structure of C. crescentus GcrA-TACup 分子名称: Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... 著者 Wu, X.X, Zhang, Y. 登録日 2022-07-05 公開日 2023-01-18 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
7YE2	The cryo-EM structure of C. crescentus GcrA-TACdown 分子名称: Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... 著者 Wu, X.X, Zhang, Y. 登録日 2022-07-05 公開日 2023-01-18 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
8AD1	RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Dey, S, Weixlbaumer, A. 登録日 2022-07-07 公開日 2022-10-19 最終更新日 2022-11-02 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8GZG	Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Shen, L.Q, You, L.L, Zhang, Y. 登録日 2022-09-27 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Proc.Natl.Acad.Sci.USA, 2023

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