PDB: 285 件ウェブページステータス検索Chemie searchBIRD

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8T41	Crystal structure of aminopeptidase N from Mycobacterium tuberculosis 分子名称: Aminopeptidase N, MAGNESIUM ION, ZINC ION 著者 Park, H.W, Moss, D.L, Landry, S.J. 登録日 2023-06-08 公開日 2024-04-17 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of aminopeptidase N from Mycobacterium tuberculosis To Be Published
8T6H	X-ray crystal structure of PfA-M1(E319A) 分子名称: Aminopeptidase N, GLYCEROL, MAGNESIUM ION, ... 著者 Webb, C.T, McGowan, S. 登録日 2023-06-16 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase. To Be Published
8T83	X-ray crystal structure of PfA-M1(M462K) 分子名称: Aminopeptidase N, GLYCEROL, ZINC ION 著者 Yang, W, Drinkwater, N, Webb, C.T, McGowan, S. 登録日 2023-06-21 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase. To Be Published
8T7P	X-ray crystal structure of PfA-M1(M462S) 分子名称: Aminopeptidase N, GLYCEROL, MAGNESIUM ION, ... 著者 Yang, W, Drinkwater, N, Webb, C.T, McGowan, S. 登録日 2023-06-21 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase. To Be Published
8QOW	LTA4 hydrolase in complex with compound 2(S) 分子名称: (2~{S})-2-azanyl-3-[3-[4-[3-fluoranyl-5-(1~{H}-pyrazol-5-yl)pyridin-2-yl]oxyphenyl]pyrazol-1-yl]propan-1-ol, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2023-09-29 公開日 2023-12-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J.Med.Chem., 66, 2023
8QPN	LTA4 hydrolase in complex with compound 6(S) 分子名称: (2S)-2-azanyl-3-[5-[4-(5-chloranyl-3-fluoranyl-pyridin-2-yl)oxyphenyl]-1,2,3,4-tetrazol-2-yl]propan-1-ol, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2023-10-02 公開日 2023-12-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J.Med.Chem., 66, 2023
8QQ4	LTA4 hydrolase in complex with compound 6(R) 分子名称: (2R)-2-azanyl-3-[5-[4-(5-chloranyl-3-fluoranyl-pyridin-2-yl)oxyphenyl]-1,2,3,4-tetrazol-2-yl]propan-1-ol, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2023-10-03 公開日 2023-12-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J.Med.Chem., 66, 2023
8RX3	LTA4 hydrolase in complex with CTX-4430 分子名称: 4-[[(1~{S},4~{S})-5-[[4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl]methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]benzoic acid, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2024-02-06 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. J.Med.Chem., 67, 2024
8RX9	LTA4 hydrolase in complex with compound3 分子名称: 1-[[5-[5-(1~{H}-pyrazol-5-yl)pyridin-2-yl]oxypyridin-2-yl]methyl]piperidin-4-ol, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2024-02-06 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. J.Med.Chem., 67, 2024
8RX7	LTA4 hydrolase in complex with compound2 分子名称: 5-(4-phenoxyphenyl)-1~{H}-imidazole, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2024-02-06 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. J.Med.Chem., 67, 2024

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