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1POB
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CRYSTAL STRUCTURE OF COBRA-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
分子名称: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2
著者White, S.P, Scott, D.L, Otwinowski, Z, Sigler, P.B.
登録日1992-09-07
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
1QLL
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Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai
分子名称: N-TRIDECANOIC ACID, PHOSPHOLIPASE A2
著者Lee, W.-H, Polikarpov, I.
登録日1999-09-01
公開日2000-09-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid
Biochemistry, 40, 2001
1OXL
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INHIBITION OF PHOSPHOLIPASE A2 (PLA2) BY (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)-ACETIC ACID (INDOLE): CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PLA2 FROM RUSSELL'S VIPER AND INDOLE AT 1.8 RESOLUTION
分子名称: (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID, CARBONATE ION, Phospholipase A2 VRV-PL-VIIIa, ...
著者Chandra, V, Balasubramanya, R, Kaur, P, Singh, T.P.
登録日2003-04-02
公開日2004-04-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex of the secretory phospholipase A2 from Daboia russelli pulchella with an endogenic indole derivative, 2-carbamoylmethyl-5-propyl-octahydro-indol-7-yl-acetic acid at 1.8 A resolution.
Biochim.Biophys.Acta, 1752, 2005
1PA0
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CRYSTAL STRUCTURE OF BNSP-7, A LYS49-PHOSPHOLIPASE A2
分子名称: Myotoxic phospholipase A2-like
著者Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.
登録日2003-05-13
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
1OQS
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BU of 1oqs by Molmil
Crystal Structure of RV4/RV7 Complex
分子名称: Phospholipase A2 RV-4, Phospholipase A2 RV-7
著者Perbandt, M, Betzel, C.
登録日2003-03-11
公開日2003-09-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the heterodimeric neurotoxic complex viperotoxin F (RV-4/RV-7) from the venom of Vipera russelli formosensis at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1RGB
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Phospholipase A2 from Vipera ammodytes meridionalis
分子名称: (9E)-OCTADEC-9-ENAMIDE, Phospholipase A2
著者Georgieva, D.N.
登録日2003-11-12
公開日2005-01-18
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition.
Biochem.Biophys.Res.Commun., 319, 2004
1SFV
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PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M.
登録日1996-02-20
公開日1996-07-11
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor.
J.Biomol.NMR, 5, 1995
1TP2
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Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
分子名称: ACETIC ACID, N-TRIDECANOIC ACID, Phospholipase A2 VRV-PL-VIIIa, ...
著者Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
登録日2004-06-15
公開日2004-06-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the complex of group II phospholipaseA2 dimer with a fatty acid tridecanoic acid at 2.4 A resolution
To be Published
1U73
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Crystal structure of a Dimeric Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A2 from Bothrops jararacussu
分子名称: hypotensive phospholipase A2
著者Magro, A.J, Murakami, M.T, Soares, A.M, Arni, R.K, Fontes, M.R.
登録日2004-08-02
公開日2004-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) in the monomeric and dimeric states: insights into its oligomeric state
Biochem.Biophys.Res.Commun., 323, 2004
1U4J
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Crystal structure of a carbohydrate induced dimer of group I phospholipase A2 from Bungarus caeruleus at 2.1 A resolution
分子名称: ACETIC ACID, CHLORIDE ION, SODIUM ION, ...
著者Singh, G, Gourinath, S, Sharma, S, Bhanumathi, S, Betzel, C, Srinivasan, A, Singh, T.P.
登録日2004-07-26
公開日2004-08-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Crystal structure of a carbohydrate induced homodimer of phospholipase A(2) from Bungarus caeruleus at 2.1A resolution
J.Struct.Biol., 149, 2005
1S6B
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X-ray Crystal Structure of a Complex Formed Between Two Homologous Isoforms of Phospholipase A2 from Naja naja sagittifera: Principle of Molecular Association and Inactivation
分子名称: ACETIC ACID, CALCIUM ION, PHOSPHATE ION, ...
著者Jabeen, T, Sharma, S, Singh, R.K, Kaur, P, Singh, T.P.
登録日2004-01-23
公開日2004-02-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a calcium-induced dimer of two isoforms of cobra phospholipase A2 at 1.6 A resolution.
Proteins, 59, 2005
1S8I
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Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, second fatty acid free form
分子名称: Phospholipase A2 homolog, SULFATE ION
著者Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C.
登録日2004-02-02
公開日2004-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.609 Å)
主引用文献A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
1TG1
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Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor PHQ-Leu-Val-Arg-Tyr at 1.2A resolution
分子名称: ACETIC ACID, METHANOL, Phospholipase A2, ...
著者Singh, N, Kaur, P, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Singh, T.P.
登録日2004-05-28
公開日2004-06-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor Cbz-dehydro-Leu-Val-Arg-Tyr at 1.2A resolution
To be Published
1S8G
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Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form
分子名称: GLYCEROL, LAURIC ACID, Phospholipase A2 homolog, ...
著者Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C.
登録日2004-02-02
公開日2004-02-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
1UNE
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CARBOXYLIC ESTER HYDROLASE, 1.5 ANGSTROM ORTHORHOMBIC FORM OF THE BOVINE RECOMBINANT PLA2
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Sundaralingam, M.
登録日1997-11-05
公開日1998-05-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-resolution refinement of orthorhombic bovine pancreatic phospholipase A2.
Acta Crystallogr.,Sect.D, 55, 1999
1VAP
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BU of 1vap by Molmil
THE MONOMERIC ASP49 SECRETORY PHOSPHOLIPASE A2 FROM THE VENOM OF AGKISTRIDON PISCIVORUS PISCIVORUS
分子名称: PHOSPHOLIPASE A2
著者Scott, D.L.
登録日1996-11-15
公開日1997-07-07
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural aspects of interfacial adsorption. A crystallographic and site-directed mutagenesis study of the phospholipase A2 from the venom of Agkistrodon piscivorus piscivorus.
J.Biol.Chem., 272, 1997
1SKG
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Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser
分子名称: METHANOL, Phospholipase A2, SULFATE ION, ...
著者Ethayathulla, A.S, Singh, N, Sharma, S, Makker, J, Dey, S, Perbandt, M, Betzel, C, Singh, T.P.
登録日2004-03-04
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser
To be Published
1SFW
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BU of 1sfw by Molmil
PORCINE PANCREAS PHOSPHOLIPASE A2, NMR, 18 STRUCTURES
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Van Den Berg, B, Tessari, M, Boelens, R, Dijkman, R, Kaptein, R, De Haas, G.H, Verheij, H.M.
登録日1996-02-23
公開日1996-07-11
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor.
J.Biomol.NMR, 5, 1995
1UMV
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BU of 1umv by Molmil
Crystal structure of an acidic, non-myotoxic phospholipase A2 from the venom of Bothrops jararacussu
分子名称: CALCIUM ION, HYPOTENSIVE PHOSPHOLIPASE A2
著者Murakami, M.T, Watanabe, L, Cintra, A.C.O, Arni, R.K.
登録日2003-08-28
公開日2003-09-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal Structure of an Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A(2) in the Monomeric and Dimeric States: Insights Into its Oligomeric State
Biochem.Biophys.Res.Commun., 323, 2004
1SV3
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Structure of the complex formed between Phospholipase A2 and 4-methoxybenzoic acid at 1.3A resolution.
分子名称: 4-METHOXYBENZOIC ACID, Phospholipase A2, SULFATE ION
著者Singh, N, Prahathees, E, Jabeen, T, Pal, A, Ethayathulla, A.S, Prem kumar, R, Sharma, S, Singh, T.P.
登録日2004-03-27
公開日2004-04-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
1SXK
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Crystal Structure of a complex formed between phospholipase A2 and a non-specific anti-inflammatory amino salicylic acid at 1.2 A resolution
分子名称: 2-HYDROXY-4-AMINOBENZOIC ACID, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Bilgrami, S, Kaur, P, Sharma, S, Singh, T.P.
登録日2004-03-31
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Crystal Structure of a complex formed between phospholipase A2 and a non-specific anti-inflammatory amino salicylic acid at 1.2 A resolution
To be Published
1T37
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Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between group I phospholipase A2 and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.6A resolution
分子名称: ACETATE ION, Phospholipase A2 isoform 3, Synthetic peptide
著者Singh, R.K, Singh, N, Jabeen, T, Makker, J, Sharma, S, Dey, S, Singh, T.P.
登録日2004-04-25
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution.
J.Drug Target., 13, 2005
1TH6
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Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution
分子名称: (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, Phospholipase A2, SULFATE ION
著者Singh, N, Pal, A, Jabeen, T, Sharma, S, Perbandt, M, Betzel, C, Singh, T.P.
登録日2004-06-01
公開日2004-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution
To be Published
1TK4
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Crystal structure of russells viper phospholipase A2 in complex with a specifically designed tetrapeptide Ala-Ile-Arg-Ser at 1.1 A resolution
分子名称: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, Tetrapeptide Ala-Ile-Arg-Ser
著者Singh, N, Bilgrami, S, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Kaur, P, Singh, T.P.
登録日2004-06-08
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structure of russells viper phospholipase A2 with a specifically designed tetrapeptide Ala-Ile-Arg-Ser at 1.1 A resolution
TO BE PUBLISHED
1TC8
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Crystal structure of Krait-venom phospholipase A2 in a complex with a natural fatty acid tridecanoic acid
分子名称: N-TRIDECANOIC ACID, SODIUM ION, phospholipase A2 isoform 1
著者Singh, G, Jasti, J, Saravanan, K, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P.
登録日2004-05-21
公開日2004-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the complex formed between a group I phospholipase A2 and a naturally occurring fatty acid at 2.7 A resolution
PROTEIN SCI., 14, 2005

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