PDB: 230764 件ウェブページステータス検索Chemie searchBIRD

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6H7Y	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 1-79-1 分子名称: (2~{S})-2-[[(2~{S})-6-[(4-fluorophenyl)amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Motlova, L, Novakova, Z, Barinka, C. 登録日 2018-07-31 公開日 2018-12-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics. ACS Med Chem Lett, 9, 2018
6H6G	Crystal Structure of TcdB2-TccC3 without hypervariable C-terminal region 分子名称: TcdB2,TccC3 著者 Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. 登録日 2018-07-27 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature, 563, 2018
6H7Z	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 2-65-1 分子名称: (2~{S})-2-[[(2~{S})-6-[(6-fluoranylpyridin-3-yl)-methyl-amino]-1-oxidanyl-1,6-bis(oxidanylidene)hexan-2-yl]carbamoylamino]pentanedioic acid, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Motlova, L, Novakova, Z, Barinka, C. 登録日 2018-07-31 公開日 2018-12-05 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics. ACS Med Chem Lett, 9, 2018
6YWA	Human REF STING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] 分子名称: 3',3'-c-[2'FdAMP-2'FdAM(PS)], GLYCEROL, Stimulator of interferon genes protein 著者 Boura, E, Smola, M. 登録日 2020-04-29 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.311 Å) 主引用文献 Human REF STING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] To Be Published
6YWB	Human wtSTING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] 分子名称: 3',3'-c-[2'FdAMP-2'FdAM(PS)], Stimulator of interferon protein 著者 Boura, E, Smola, M. 登録日 2020-04-29 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Human wtSTING in complex with 3',3'-c-[2'FdAMP-2'FdAM(PS)] To Be Published
8CEO	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2023-02-02 公開日 2023-03-08 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
6ZPP	g7941: a virulence factor from Drechmaria coniospora 分子名称: CHLORIDE ION, virulence factor 著者 Leone, P, Roussel, A, Zimberger, C. 登録日 2020-07-09 公開日 2022-01-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a virulence factor from Drechmaria coniospora, a C. elegans pathogen To Be Published
8CEN	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Schilbach, S, Cramer, P. 登録日 2023-02-02 公開日 2023-03-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
8D1P	Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 7-Deaza-2'-C-methyladenosine 分子名称: 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Chaperone DnaK, SULFATE ION 著者 Mrozek, A, Chen, Y, Antoshchenko, T, Park, H.W. 登録日 2022-05-27 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. Front Mol Biosci, 9, 2022
7RKI	Griffithsin-S10Y/S42Y/S88Y 分子名称: Griffithsin, alpha-D-mannopyranose 著者 Sun, J.D, Zhao, G.X. 登録日 2021-07-22 公開日 2022-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17, 2022
6P2E	Structure of Aedes aegypti OBP22 in the complex with benzaldehyde 分子名称: BENZOIC ACID, GLYCEROL, OBP22, ... 著者 Jones, D.N, Murphy, E. 登録日 2019-05-21 公開日 2019-07-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
7NNA	Toxin Import Through the Antibiotic Efflux Channel TolC 分子名称: Klebicin C activity 著者 Lowe, E.D, Kleanthous, C, Housden, N.G. 登録日 2021-02-24 公開日 2021-07-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Toxin import through the antibiotic efflux channel TolC. Nat Commun, 12, 2021
7Q24	Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD011 分子名称: (2~{S})-2-[[(2~{S})-1-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]amino]-4-phenyl-butanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
7Q26	Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD013 分子名称: (2~{S},5~{R})-5-(4-methylphenyl)-1-[2-[[(2~{S})-1-oxidanyl-1-oxidanylidene-4-phenyl-butan-2-yl]amino]ethanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
7Q25	Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with dual ACE/NEP inhibitor AD012 分子名称: (2~{S})-2-[[(2~{S})-1-[[(2~{S})-3-(4-hydroxyphenyl)-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-hexan-2-yl]amino]-4-phenyl-butanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2021-10-23 公開日 2022-02-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the Requirements for Dual Angiotensin-Converting Enzyme C-Domain Selective/Neprilysin Inhibition. J.Med.Chem., 65, 2022
6XCX	Nitric Oxide Synthase from Bacillus subtilis in complex with N2-((3-((2-aminoquinolin-7-yl)methoxy)phenoxy)methyl)pyridine-2,6-diamine 分子名称: 7-{[3-(2-{[(6-aminopyridin-2-yl)methyl]amino}ethoxy)phenoxy]methyl}quinolin-2-amine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Lewis, M.C, Poulos, T.L. 登録日 2020-06-09 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2520268 Å) 主引用文献 Selective Anti-MRSA inhibitors targeting Nitric Oxide Synthase To Be Published
7OJR	Bacillus subtilis phosphoglucomutase GlmM (phosphate bound) 分子名称: PHOSPHATE ION, Phosphoglucosamine mutase 著者 Pathania, M, Grundling, A.G, Freemont, P. 登録日 2021-05-17 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM. J.Biol.Chem., 297, 2021
6Y3J	RING-DTC domains of Deltex 2, bound to ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Probable E3 ubiquitin-protein ligase DTX2, ZINC ION 著者 Gabrielssen, M, Buetow, L, Huang, D.T. 登録日 2020-02-18 公開日 2020-09-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv, 6, 2020
6O5E	Crystal structure of the Vitronectin hemopexin-like domain 分子名称: CHLORIDE ION, IMIDAZOLE, NITRATE ION, ... 著者 Lechtenberg, B.C, Shin, K, Marassi, F.M. 登録日 2019-03-01 公開日 2019-09-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of human Vitronectin C-terminal domain and interaction withYersinia pestisouter membrane protein Ail. Sci Adv, 5, 2019
6OTL	Structure of Aedes aegypti OBP22 in the complex with benzaldehyde 分子名称: AAEL005772-PA, BENZOIC ACID, HEXATANTALUM DODECABROMIDE, ... 著者 Jones, D.N, Murphy, E. 登録日 2019-05-03 公開日 2019-06-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
6Y22	RING-DTC domains of Deltex 2, Form 1 分子名称: Probable E3 ubiquitin-protein ligase DTX2, ZINC ION 著者 Gabrielssen, M, Buetow, L, Huang, D.T. 登録日 2020-02-14 公開日 2020-09-02 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.069 Å) 主引用文献 DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv, 6, 2020
6NBN	Structure of Aedes aegypti OBP22 in the complex with arachidonic acid 分子名称: AAEL005772-PA, ARACHIDONIC ACID 著者 Jones, D.N, Wang, J. 登録日 2018-12-07 公開日 2018-12-19 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
7O38	cytochrome C kustc0562 from Kuenenia stuttgartiensis 分子名称: CHLORIDE ION, Cytochrome c-552 Ks_3357, HEME C, ... 著者 Bock, J, Akram, M, Barends, T. 登録日 2021-04-01 公開日 2021-10-13 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Specificity of Small c -Type Cytochromes in Anaerobic Ammonium Oxidation. Acs Omega, 6, 2021
5L3M	D11 bound [S39_PQ]-IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
8BR4	Structure of GAPDH from Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Kumar, A, Karthikeyan, S. 登録日 2022-11-22 公開日 2023-11-01 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Stoichiometry of ligand binding and role of C-terminal lysines in Mycobacterium tuberculosis and human GAPDH multifunctionality. Febs J., 2024

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