6H7Y

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 1-79-1

Summary for 6H7Y

• Entry DOI: 10.2210/pdb6h7y/pdb
• Descriptor: Glutamate carboxypeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, DI(HYDROXYETHYL)ETHER, ... (14 entities in total)
• Functional Keywords: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; urea based inhibitor, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 84623.23

Authors

Motlova, L.,Novakova, Z.,Barinka, C. (deposition date: 2018-07-31, release date: 2018-12-05, Last modification date: 2024-01-17)

• Primary citation: Nakajima, R.,Novakova, Z.,Tueckmantel, W.,Motlova, L.,Barinka, C.,Kozikowski, A.P.; 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics.; ACS Med Chem Lett, 9:1099-1104, 2018; PubMed: 30429952; DOI: 10.1021/acsmedchemlett.8b00318

Experimental method

X-RAY DIFFRACTION (1.81 Å)