7UZV
| Cytoplasmic domains of Band 3-I (local refinement from consensus reconstruction of ankyrin complexes) | 分子名称: | Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-09 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0Q
| Local refinement of protein 4.2, class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Protein 4.2 | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-10 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0U
| Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-11 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7UZQ
| Local refinement of RhAG-RhCE-ANK1(AR1-5), from consensus refinement of all classes | 分子名称: | Ammonium transporter Rh type A, Ankyrin-1, Blood group Rh(CE) polypeptide, ... | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-09 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.17 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7UZU
| Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus reconstruction; bound to N-terminal peptide from band 3) | 分子名称: | Ankyrin-1, Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-09 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0T
| Local refinement of Band 3-I cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-11 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0S
| Local refinement of RhAG/CE trimer, class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Ammonium transporter Rh type A, Ankyrin-1, Blood group Rh(CE) polypeptide, ... | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-10 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0Y
| Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-11 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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7V0M
| Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex | 分子名称: | Ankyrin-1, Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-10 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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1P97
| NMR structure of the C-terminal PAS domain of HIF2a | 分子名称: | Endothelial PAS domain protein 1 | 著者 | Erbel, P.J, Card, P.B, Karakuzu, O, Bruick, R.K, Gardner, K.H. | 登録日 | 2003-05-09 | 公開日 | 2004-01-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor. Proc.Natl.Acad.Sci.USA, 100, 2003
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7ABF
| Human pre-Bact-1 spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-09 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7AAV
| Human pre-Bact-2 spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-04 | 公開日 | 2020-12-09 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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1DR3
| 2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN | 分子名称: | 7,8-DIHYDROBIOPTERIN, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... | 著者 | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | 登録日 | 1992-03-14 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes. Biochemistry, 32, 1993
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1DR2
| 2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN | 分子名称: | 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, DIHYDROFOLATE REDUCTASE | 著者 | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | 登録日 | 1992-03-14 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes. Biochemistry, 32, 1993
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8CSX
| Local refinement of RhAG/CE trimer in class 2 of erythrocyte ankyrin-1 complex | 分子名称: | Ammonium transporter Rh type A, Blood group Rh(CE) polypeptide, CHOLESTEROL, ... | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-13 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8CSV
| Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of erythrocyte ankyrin-1 complex | 分子名称: | Ankyrin-1, Band 3 anion transport protein | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-13 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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6WD9
| Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure III-B) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Korostelev, A.A. | 登録日 | 2020-03-31 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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1E1H
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6ZFB
| Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer) | 分子名称: | DNA helicase, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Pei, H.-P, Hilal, T, Huang, Y.-H, Said, N, Loll, B, Wahl, M.C. | 登録日 | 2020-06-17 | 公開日 | 2020-10-14 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The delta subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling. Nat Commun, 11, 2020
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8DVW
| Structure of the Campylobacter concisus glycosyltransferase PglA R203Q | 分子名称: | N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | 著者 | Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N. | 登録日 | 2022-07-30 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA. Protein Sci., 33, 2024
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8DVZ
| Structure of the Campylobacter concisus glycosyltransferase PglA R282V variant | 分子名称: | N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | 著者 | Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N. | 登録日 | 2022-07-30 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA. Protein Sci., 33, 2024
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8DQD
| Structure of the Campylobacter concisus glycosyltransferase PglA | 分子名称: | N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | 著者 | Vuksanovic, N, Clasman, J.R, Bernstein, H.M, Imperiali, B, Allen, K.N. | 登録日 | 2022-07-18 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA. Protein Sci., 33, 2024
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8C14
| Aurora A kinase in complex with TPX2-inhibitor 9 | 分子名称: | (1~{R},2~{R})-cyclohexane-1,2-dicarboxylic acid, 4-(4-chloranyl-3-cyano-phenyl)-1~{H}-indole-6-carboxylic acid, ACETATE ION, ... | 著者 | Fischer, G, Rocaboy, M, Blaszczyk, B, Moschetti, T, Wang, X, Scott, D.E, Coyne, A.G, Dagostin, C, Rooney, T, Bayly, A, Feng, J, Asteian, A, Alcaide-Lopez, A, Stockwell, S, Skidmore, J, Venkitaraman, A.R, Abell, C, Blundell, T.L, Hyvonen, M. | 登録日 | 2022-12-20 | 公開日 | 2024-01-10 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. J.Med.Chem., 67, 2024
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8C1D
| Aurora A kinase in complex with TPX2-inhibitor 9 | 分子名称: | (1~{R},2~{R})-cyclohexane-1,2-dicarboxylic acid, 4-(4-chlorophenyl)-7-methyl-1~{H}-indole-6-carboxylic acid, ACETATE ION, ... | 著者 | Fischer, G, Rocaboy, M, Blaszczyk, B, Moschetti, T, Wang, X, Scott, D.E, Coyne, A.G, Dagostin, C, Rooney, T, Bayly, A, Feng, J, Asteian, A, Alcaide-Lopez, A, Stockwell, S, Skidmore, J, Venkitaraman, A.R, Abell, C, Blundell, T.L, Hyvonen, M. | 登録日 | 2022-12-20 | 公開日 | 2024-01-10 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (2.115 Å) | 主引用文献 | Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. J.Med.Chem., 67, 2024
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8C1H
| Aurora A kinase in complex with TPX2-inhibitor 8 | 分子名称: | (1~{R},2~{R})-cyclohexane-1,2-dicarboxylic acid, 4-(4-chloranyl-3-pyrazin-2-yloxy-phenyl)-~{N}-(dimethylsulfamoyl)-7-methyl-1~{H}-indole-6-carboxamide, ACETATE ION, ... | 著者 | Fischer, G, Rocaboy, M, Blaszczyk, B, Moschetti, T, Wang, X, Scott, D.E, Coyne, A.G, Dagostin, C, Rooney, T, Bayly, A, Feng, J, Asteian, A, Alcaide-Lopez, A, Stockwell, S, Skidmore, J, Venkitaraman, A.R, Abell, C, Blundell, T.L, Hyvonen, M. | 登録日 | 2022-12-20 | 公開日 | 2024-01-10 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | 主引用文献 | Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. J.Med.Chem., 67, 2024
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