PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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206D	BASE-PAIR OPENING AND SPERMINE BINDING-B-DNA FEATURES DISPLAYED IN THE CRYSTAL STRUCTURE OF A GAL OPERON FRAGMENT: IMPLICATIONS FOR PROTEIN-DNA RECOGNITION 分子名称: DNA (5'-D(*CP*CP*AP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*TP*GP*G)-3'), SPERMINE 著者 Tari, L.W, Secco, A.S. 登録日 1995-04-19 公開日 1996-06-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Base-pair opening and spermine binding--B-DNA features displayed in the crystal structure of a gal operon fragment: implications for protein-DNA recognition. Nucleic Acids Res., 23, 1995
4B0Q	Lead Generation of BACE1 Inhibitors by Coupling Non-amidine New Warheads to a Known Binding Scaffold 分子名称: 2-[[3-(3-methoxyphenyl)phenyl]-(4-pyridyl)methyl]guanidine, ACETATE ION, BETA-SECRETASE 1 著者 Pendrill, R, Kolmodin, K, Johansson, P, Plobeck, N. 登録日 2012-07-04 公開日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Lead Generation of Bace1 Inhibitors by Coupling Non-Amidine New Warheads to a Known Binding Scaffold To be Published
4ASD	Crystal Structure of VEGFR2 (Juxtamembrane and Kinase Domains) in Complex with SORAFENIB (BAY 43-9006) 分子名称: 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 著者 McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A. 登録日 2012-04-30 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
2DKB	DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES 分子名称: 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Toney, M.D, Hohenester, E, Jansonius, J.N. 登録日 1994-07-12 公開日 1994-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites. Science, 261, 1993
4AU3	Crystal Structure of a Hsp47-collagen complex 分子名称: 18ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47 ), ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-14 公開日 2012-08-15 最終更新日 2012-08-29 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
5V6D	Crystal structure of nucleoside diphosphate kinase from Neisseria gonorrhoeae in complex with citrate 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Nucleoside diphosphate kinase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-03-16 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of nucleoside diphosphate kinase from Neisseria gonorrhoeae in complex with citrate To be Published
4B3V	Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 20mM of Calcium Acetate 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Vaney, M.C, DuBois, R.M, Tortorici, M.A, Rey, F.A. 登録日 2012-07-26 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1. Nature, 493, 2013
4AY9	Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ... 著者 Jiang, X, Liu, H, Chen, X, He, X. 登録日 2012-06-19 公開日 2012-08-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor. Proc.Natl.Acad.Sci.USA, 109, 2012
294D	INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE 分子名称: DNA (5'-D(*AP*AP*CP*CP*CP*C)-3') 著者 Cai, L, Chen, L, Raghavan, S, Ratliff, R, Moyzis, R, Rich, A. 登録日 1996-10-30 公開日 1998-10-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere. Nucleic Acids Res., 26, 1998
4AYF	Crystal structure of the complex of the Caf1M:Caf1 chaperone:subunit preassembly complex carrying the Tyr40Ala mutation in the Caf1M chaperone 分子名称: CHAPERONE PROTEIN CAF1M, F1 CAPSULE ANTIGEN 著者 Yu, X.D, Dubnovitsky, A, Pudney, A.F, MacIntyre, S, Knight, S.D, Zavialov, A.V. 登録日 2012-06-20 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Allosteric Mechanism Controls Traffic in the Chaperone/Usher Pathway. Structure, 20, 2012
2DL2	KILLER IMMUNOGLOBULIN RECEPTOR 2DL2 分子名称: PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR (P58 NATURAL KILLER CELL RECEPTOR CLONE CL-43)) 著者 Sun, P, Snyder, G. 登録日 1999-03-08 公開日 1999-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2 Proc.Natl.Acad.Sci.USA, 96, 1999
2A0Y	Structure of human purine nucleoside phosphorylase H257D mutant 分子名称: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION 著者 Murkin, A.S, Shi, W, Schramm, V.L. 登録日 2005-06-17 公開日 2006-06-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Neighboring group participation in the transition state of human purine nucleoside phosphorylase. Biochemistry, 46, 2007
4B1C	New Aminoimidazoles as BACE-1 Inhibitors: From Rational Design to Ab- lowering in Brain 分子名称: (2R)-2-cyclopropyl-5-methyl-2-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-2H-imidazol-4-amine, BETA-SECRETASE 1, DIMETHYL SULFOXIDE 著者 Rahm, F, Blid, J, Ginman, T, Karlstrom, S, Kihlstrom, J, Kolmodin, K, Lindstrom, J, von Berg, S, von Kieseritzky, F, Slivo, C, Swahn, B, Viklund, J, Olsson, L, Johansson, P, Eketjall, S, Falting, J, Jeppsson, F, Stromberg, K, Janson, J, Gravenfors, Y. 登録日 2012-07-10 公開日 2012-10-10 最終更新日 2018-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (A beta ) lowering in brain. J. Med. Chem., 55, 2012
2A3A	Crystal structure of Aspergillus fumigatus chitinase B1 in complex with theophylline 分子名称: SULFATE ION, THEOPHYLLINE, chitinase 著者 Rao, F.V, Andersen, O.A, Vora, K.A, DeMartino, J.A, van Aalten, D.M.F. 登録日 2005-06-24 公開日 2005-09-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes. Chem.Biol., 12, 2005
2AAR	Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome. 分子名称: 23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L29, ... 著者 Baram, D, Pyetan, E, Sittner, A, Auerbach-Nevo, T, Bashan, A, Yonath, A. 登録日 2005-07-14 公開日 2005-08-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action Proc.Natl.Acad.Sci.Usa, 102, 2005
4AYH	The X-ray structure of zinc bound ZinT 分子名称: METAL-BINDING PROTEIN YODA, SULFATE ION, ZINC ION 著者 Alaleona, F, Ilari, A, Battistoni, A, Petrarca, P, Chiancone, E. 登録日 2012-06-21 公開日 2013-07-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The Salmonella Enterica Zint Structure, Zinc Affinity and Interaction with the High-Affinity Uptake Protein Znua Provide Insight Into the Management of Periplasmic Zinc. Biochim.Biophys.Acta, 1840, 2014
5UW5	PCY1 H695A Variant in Complex with Follower Peptide 分子名称: CACODYLATE ION, CALCIUM ION, Peptide cyclase 1, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2017-02-20 公開日 2017-05-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4ARN	Crystal structure of the N-terminal domain of Drosophila Toll receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MALONATE ION, ... 著者 Gangloff, M, Gay, N.J. 登録日 2012-04-25 公開日 2013-01-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor. Structure, 21, 2013
4AS8	X-ray structure of the cyan fluorescent protein Cerulean cryoprotected with ethylene glycol 分子名称: 1,2-ETHANEDIOL, GREEN FLUORESCENT PROTEIN, MAGNESIUM ION 著者 von Stetten, D, Batot, G, Noirclerc-Savoye, M, Royant, A. 登録日 2012-04-29 公開日 2012-10-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Alteration of Fluorescent Protein Spectroscopic Properties Upon Cryoprotection Acta Crystallogr.,Sect.D, 68, 2012
5UND	Crystal Structure of CTCF(ZnF 4-10) With 28-mer DNA 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-01-30 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.549 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
4B5Y	X-ray structure of the cyan fluorescent protein mTurquoise-GL (K206A mutant) in space group C222(1) 分子名称: GREEN FLUORESCENT PROTEIN 著者 von Stetten, D, Lelimousin, M, Oost, K, Noirclerc-Savoye, M, Gadella, T.W.J, Goedhart, J, Royant, A. 登録日 2012-08-08 公開日 2013-08-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Influence of the H148G Mutation on Fluorescence Properties of Cyan Fluorescent Proteins To be Published
5UO8	Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-aminoquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Chreifi, G, Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
2AFI	Crystal Structure of MgADP bound Av2-Av1 Complex 分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. 登録日 2005-07-25 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Nitrogenase Complexes: Multiple Docking Sites for a Nucleotide Switch Protein Science, 309, 2005
4AW4	Engineered variant of Listeria monocytogenes InlB internalin domain with an additional leucine rich repeat inserted 分子名称: GLYCEROL, INTERNALIN B, SULFATE ION 著者 Niemann, H.H, Heinz, D.W. 登録日 2012-05-31 公開日 2012-08-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Engineered Variants of Inlb with an Additional Leucine-Rich Repeat Discriminate between Physiologically Relevant and Packing Contacts in Crystal Structures of the Inlb:Met Complex. Protein Sci., 21, 2012
4B78	Aminoimidazoles as BACE-1 Inhibitors: From De Novo Design to Ab- lowering in Brain 分子名称: (3R,5R)-3-methoxy-5-(4-methoxyphenyl)-5-(3-pyridin-3-ylphenyl)-3,4-dihydropyrrol-2-amine, BETA-SECRETASE 1 著者 Gravenfors, Y, Blid, J, Ginman, T, Karlstrom, S, Kihlstrom, J, Kolmodin, K, Lindstrom, J, Berg, S, Kieseritzky, F, Slivo, C, Swahn, B, Viklund, J, Olsson, L, Johansson, P, Eketjall, S, Falting, J, Jeppsson, F, Stromberg, K, Janson, J, Rahm, F. 登録日 2012-08-16 公開日 2013-06-26 最終更新日 2013-07-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity. J.Med.Chem., 56, 2013

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