4AU3

Crystal Structure of a Hsp47-collagen complex

Summary for 4AU3

• Entry DOI: 10.2210/pdb4au3/pdb
• Related: 4AWR
• Descriptor: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47 ), MEMBER 1, (COLLAGEN BINDING PROTEIN 1), SERPYIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47 ), MEMBER 1, (COLLAGEN BINDING PROTEIN 1), 18ER COLLAGEN MODEL PEPTIDE 15-R8 (3 entities in total)
• Functional Keywords: chaperone-peptide complex, chaperone, chaperone/peptide
• Biological source: CANIS LUPUS FAMILIARIS (DOG); More
• Cellular location: Secreted, extracellular space, extracellular matrix: E2RHY7
• Total number of polymer chains: 10
• Total formula weight: 189248.20

Authors

Widmer, C.,Gebauer, J.M.,Brunstein, E.,Rodenbaum, S.,Zaucke, F.,Drogemuller, C.,Leeb, T.,Baumann, U. (deposition date: 2012-05-14, release date: 2012-08-15, Last modification date: 2012-08-29)

• Primary citation: Widmer, C.,Gebauer, J.M.,Brunstein, E.,Rosenbaum, S.,Zaucke, F.,Drogemuller, C.,Leeb, T.,Baumann, U.; Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.; Proc.Natl.Acad.Sci.USA, 109:13243-, 2012; PubMed: 22847422; DOI: 10.1073/PNAS.1208072109

Experimental method

X-RAY DIFFRACTION (2.78 Å)