PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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5UQ9	Crystal structure of 6-phosphogluconate dehydrogenase with ((4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate 分子名称: 6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate 著者 Leonard, P.G. 登録日 2017-02-07 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Rep, 26, 2019
1Y3T	Crystal structure of YxaG, a dioxygenase from Bacillus subtilis 分子名称: FE (III) ION, Hypothetical protein yxaG 著者 Gopal, B, Madan, L.L, Betz, S.F, Kossiakoff, A.A. 登録日 2004-11-26 公開日 2005-01-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s) Biochemistry, 44, 2005
5AI8	ligand complex structure of soluble epoxide hydrolase 分子名称: 6-methyl-1,3-benzothiazol-2-amine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-02-12 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AFZ	Thrombin in complex with (2R)-2-(benzylsulfonylamino)-N-(2-((4- carbamimidoylphenyl)methylamino)-2-oxo-propyl)-3-phenyl-propanamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin-2, N-(BENZYLSULFONYL)-D-PHENYLALANYL-N-(4-CARBAMIMIDOYLBENZYL)GLYCINAMIDE, ... 著者 Ruehmann, E, Heine, A, Klebe, G. 登録日 2015-01-27 公開日 2015-08-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58, 2015
1Y1U	Structure of unphosphorylated STAT5a 分子名称: Signal transducer and activator of transcription 5A 著者 Neculai, D, Neculai, A.M, Verrier, S, Straub, K, Klumpp, K, Pfitzner, E, Becker, S. 登録日 2004-11-19 公開日 2005-10-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Structure of the unphosphorylated STAT5a dimer J.Biol.Chem., 280, 2005
3UU0	Crystal structure of L-rhamnose isomerase from Bacillus halodurans in complex with Mn 分子名称: L-rhamnose isomerase, MANGANESE (II) ION 著者 Doan, T.T.N, Prabhu, P, Kim, J.K, Jeya, M, Kang, L.W, Lee, J.K. 登録日 2011-11-27 公開日 2012-02-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based studies on the metal binding of two-metal-dependent sugar isomerases. Febs J., 281, 2014
1Y2M	Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides 分子名称: Phenylalanine ammonia-lyase 著者 Wang, L, Gamez, A, Sarkissian, C.N, Straub, M, Patch, M.G, Han, G.W, Scriver, C.R, Stevens, R.C. 登録日 2004-11-22 公開日 2005-11-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Mol.Genet.Metab., 86, 2005
5D0U	Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Tauchert, M.J, Ficner, R. 登録日 2015-08-03 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.919 Å) 主引用文献 Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 72, 2016
2AUC	Structure of the Plasmodium MTIP-MyoA complex, a key component of the parasite invasion motor 分子名称: Myosin A, Myosin A Tail Interacting Protein 著者 Bosch, J, Turley, S, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-08-27 公開日 2006-01-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor. Proc.Natl.Acad.Sci.Usa, 103, 2006
5D6O	Orthorhombic Crystal Structure of an acetylester hydrolase from Corynebacterium glutamicum 分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ... 著者 Niefind, K, Toelzer, C, Altenbuchner, J, Watzlawick, H. 登録日 2015-08-12 公開日 2015-12-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases. Febs Lett., 590, 2016
3UVA	Crystal structure of L-rhamnose isomerase mutant W38F from Bacillus halodurans in complex with Mn 分子名称: L-Rhamnose isomerase, MANGANESE (II) ION 著者 Doan, T.T.N, Prabhu, P, Jeya, M, Kim, J.K, Kang, L.W, Lee, J.K. 登録日 2011-11-29 公開日 2012-12-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structure-based studies on the metal binding of two-metal-dependent sugar isomerases. Febs J., 281, 2014
3UVX	Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac) 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, FORMIC ACID, ... 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-30 公開日 2012-01-25 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
2AVQ	Kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, AND G73S 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, ... 著者 Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. 登録日 2005-08-30 公開日 2006-01-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J.Mol.Biol., 354, 2005
4ZZ6	Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with a nucleotide, cytidine triphosphate at 2.0A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, ... 著者 Yamin, S, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. 登録日 2015-05-22 公開日 2015-06-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding and structural studies of the complexes of type 1 ribosome inactivating protein fromMomordica balsaminawith cytosine, cytidine, and cytidine diphosphate. Biochem Biophys Rep, 4, 2015
5D8G	A structural view on the dissociation of E. coli Tryptophanase 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Almog, O. 登録日 2015-08-17 公開日 2015-12-09 最終更新日 2016-07-20 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 A structural view of the dissociation of Escherichia coli tryptophanase. Acta Crystallogr.,Sect.D, 71, 2015
5A0L	N-terminal thioester domain of fibronectin-binding protein SfbI from Streptococcus pyogenes 分子名称: ACETATE ION, FIBRONECTIN-BINDING PROTEIN, ZINC ION 著者 Walden, M, Edwards, J.M, Dziewulska, A.M, Kan, S.-Y, Schwarz-Linek, U, Banfield, M.J. 登録日 2015-04-21 公開日 2015-06-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 An internal thioester in a pathogen surface protein mediates covalent host binding. Elife, 4, 2015
5A1A	2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor 分子名称: 2-phenylethyl 1-thio-beta-D-galactopyranoside, BETA-GALACTOSIDASE, MAGNESIUM ION, ... 著者 Bartesaghi, A, Merk, A, Banerjee, S, Matthies, D, Wu, X, Milne, J, Subramaniam, S. 登録日 2015-04-29 公開日 2015-05-06 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor Science, 348, 2015
5D9E	Crystal Structure of the Proline-rich Lasso Peptide Caulosegnin II 分子名称: CHLORIDE ION, Caulosegnin II 著者 Fage, C.D, Hegemann, J.D, Harms, K, Marahiel, M.A. 登録日 2015-08-18 公開日 2016-02-17 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (0.859 Å) 主引用文献 The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II. Mol Biosyst, 12, 2016
5A3M	Structure of Cea1A in complex with Chitobiose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CEA1, ... 著者 Kock, M, Brueckner, S, Wozniak, N, Veelders, M, Schlereth, J, Moesch, H.-U, Essen, L.-O. 登録日 2015-06-02 公開日 2016-06-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 High-Affinity Recognition of Non-Reducing Chitinous Ends by the Yeast Adhesin Cea1 To be Published
5D3X	Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound 分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein 著者 Cash, J.N, Tesmer, J.J.G. 登録日 2015-08-06 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
1YA7	Implications for interactions of proteasome with PAN and PA700 from the 1.9 A structure of a proteasome-11S activator complex 分子名称: GLYCEROL, Proteasome alpha subunit, Proteasome beta subunit, ... 著者 Forster, A, Masters, E.I, Whitby, F.G, Robinson, H, Hill, C.P. 登録日 2004-12-17 公開日 2005-07-26 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. Mol.Cell, 18, 2005
2AHK	Crystal structure of the met-form of the copper-bound Streptomyces castaneoglobisporus tyrosinase in complex with a caddie protein obtained by soking in cupric sulfate for 6 months 分子名称: CADDIE PROTEIN ORF378, COPPER (II) ION, NITRATE ION, ... 著者 Matoba, Y, Kumagai, T, Yamamoto, A, Yoshitsu, H, Sugiyama, M. 登録日 2005-07-28 公開日 2006-01-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis J.Biol.Chem., 281, 2006
5AHX	Apo structure of soluble epoxide hydrolase 分子名称: BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, SULFATE ION 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-02-10 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5DD1	Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques 分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN 著者 Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. 登録日 2015-08-24 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.597 Å) 主引用文献 Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
5DDD	menin in complex with MI-836 分子名称: 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(2-fluoroethyl)thieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Pollock, J, Dmitry, B, Cierpicki, T, Grembecka, J. 登録日 2015-08-24 公開日 2015-09-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes. J.Med.Chem., 58, 2015

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