PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7AKS	Human ADP-ribosylserine hydrolase ARH3 mutant E41A in complex with H2B-S7-mar peptide 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADP-ribose glycohydrolase ARH3, ... 著者 Ariza, A. 登録日 2020-10-02 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nat Commun, 12, 2021
7AOG	14-3-3 sigma in complex with Pin1 binding site pS72 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2020-10-14 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
6U6L	BRD4-BD2 in complex with the cyclic peptide 3.1_2 分子名称: AMINO GROUP, Bromodomain-containing protein 4, Cyclic peptide 3.1_2, ... 著者 Patel, K, Walshe, J.L, Walport, L.J, Mackay, J.P. 登録日 2019-08-30 公開日 2020-08-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Cyclic peptides can engage a single binding pocket through highly divergent modes. Proc.Natl.Acad.Sci.USA, 117, 2020
5OHG	enolase in complex with RNase E 分子名称: Enolase, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Du, D, Luisi, B.F. 登録日 2017-07-16 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes. Nucleic Acids Res., 46, 2018
5OID	Complex Trichoplax STIL-NTD:human CEP85 coiled coil domain 4 分子名称: Centrosomal protein of 85 kDa, Putative uncharacterized protein 著者 van Breugel, M. 登録日 2017-07-18 公開日 2018-04-18 最終更新日 2018-05-09 実験手法 X-RAY DIFFRACTION (4.6 Å) 主引用文献 Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat Commun, 9, 2018
6UFH	Co-crystal structure of M. tuberculosis ileS T-box in complex with tRNA-3'-2'3'cyclic phosphate 分子名称: MAGNESIUM ION, RNA (167-MER), RNA (77-MER) 著者 Battaglia, R.A, Grigg, J.A, Ke, A. 登録日 2019-09-24 公開日 2019-11-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.104 Å) 主引用文献 Structural basis for tRNA decoding and aminoacylation sensing by T-box riboregulators. Nat.Struct.Mol.Biol., 26, 2019
7AZ1	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1013 分子名称: 1-[4-methyl-3-(trifluoromethyl)phenyl]-2-phenyl-imidazole, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Ottmann, C. 登録日 2020-11-14 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
6UO5	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) Y363F mutant complexed with AR-42 分子名称: 1,2-ETHANEDIOL, AR-42, Histone deacetylase 6, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2019-10-14 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.43934226 Å) 主引用文献 Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6. Biochemistry, 58, 2019
5OIQ	InhA (T2A mutant) complexed with 2,6-dimethyl-3-phenylpyridin-4(1H)-one 分子名称: 2,6-dimethyl-3-phenyl-1~{H}-pyridin-4-one, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Convery, M.A. 登録日 2017-07-19 公開日 2018-02-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA. ChemMedChem, 13, 2018
5O6E	Structure of ScPif1 in complex with TTTGGGTT and ADP-AlF4 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, CHLORIDE ION, ... 著者 Lu, K.Y, Chen, W.F, Rety, S, Liu, N.N, Xu, X.G. 登録日 2017-06-06 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.345 Å) 主引用文献 Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase. Nucleic Acids Res., 46, 2018
6SD0	Structure of beta-galactosidase from Thermotoga maritima. 分子名称: Beta-galactosidase, MAGNESIUM ION 著者 Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J. 登録日 2019-07-26 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering. Acs Chem.Biol., 15, 2020
5O6S	UbV.B4R, a dimeric ubiquitin variant binding to BIRC4 RING 分子名称: Polyubiquitin-B 著者 Gabrielsen, M, Buetow, L, Huang, D.T. 登録日 2017-06-07 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68, 2017
7AY6	Crystal structure of the PDE4D catalytic domain in complex with GEBR-41b 分子名称: 1,2-ETHANEDIOL, 2-[(~{Z})-1-(3-cyclopentyloxy-4-methoxy-phenyl)ethylideneamino]oxy-1-[(2~{S},6~{S})-2,6-dimethylmorpholin-4-yl]ethanone, MAGNESIUM ION, ... 著者 Torretta, A, Abbate, S, Parisini, E. 登録日 2020-11-11 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors. Eur.J.Med.Chem., 223, 2021
5O75	Ube4B U-box domain 分子名称: SULFATE ION, Ubiquitin conjugation factor E4 B 著者 Gabrielsen, M, Buetow, L, Nakasone, M.A, Huang, D.T. 登録日 2017-06-08 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.483 Å) 主引用文献 A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68, 2017
7AX0	Crystal structure of the computationally designed Scone-E protein co-crystallized with STA form a 分子名称: Keggin (STA), PHOSPHATE ION, SconeE 著者 Mylemans, B, Vandebroek, L, Parac-Vogt, T.N, Voet, A.R.D. 登録日 2020-11-09 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of Scone: pseudosymmetric folding of a symmetric designer protein. Acta Crystallogr D Struct Biol, 77, 2021
5O79	Klebsiella pneumoniae OmpK36 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, OmpK36 著者 van den berg, B, Pathania, M. 登録日 2017-06-08 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins. Acs Infect Dis., 4, 2018
5O7U	Crystal structure of the 7-Fluorotryptophan RSL lectin in complex with Lewis x tetrasaccharide 分子名称: CALCIUM ION, MAGNESIUM ION, Putative fucose-binding lectin protein, ... 著者 Varrot, A. 登録日 2017-06-09 公開日 2018-06-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs. ACS Chem. Biol., 13, 2018
5OKB	High resolution structure of native Gan1D, a putative 6-phospho-beta-galactosidase from Geobacillus stearothermophilus 分子名称: GLYCEROL, IMIDAZOLE, PHOSPHATE ION, ... 著者 Lansky, S, Zehavi, A, Shoham, Y, Shoham, G. 登録日 2017-07-25 公開日 2017-10-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.331 Å) 主引用文献 Structural basis for enzyme bifunctionality - the case of Gan1D from Geobacillus stearothermophilus. FEBS J., 284, 2017
6SF0	Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2 in the presence of NADP+ 分子名称: Ancestral Flavin-containing monooxygenase (FMO) 2, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A. 登録日 2019-07-30 公開日 2019-12-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs. Nat.Struct.Mol.Biol., 27, 2020
5OL4	1.28 A resolution of Sporosarcina pasteurii urease inhibited in the presence of NBPT 分子名称: 1,2-ETHANEDIOL, NICKEL (II) ION, Phosphoramidothioic O,O-acid, ... 著者 Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. 登録日 2017-07-26 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Urease Inhibition in the Presence of N-(n-Butyl)thiophosphoric Triamide, a Suicide Substrate: Structure and Kinetics. Biochemistry, 56, 2017
5OLM	TRIM21 分子名称: E3 ubiquitin-protein ligase TRIM21, ZINC ION 著者 James, L.C. 登録日 2017-07-28 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21. Elife, 7, 2018
5OLR	Rhamnogalacturonan lyase 分子名称: CALCIUM ION, PHOSPHATE ION, Rhamnogalacturonan lyase, ... 著者 Basle, A, Luis, A.S, Gilbert, H.J. 登録日 2017-07-28 公開日 2017-11-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol, 3, 2018
5O9D	Crystal structure of R. ruber ADH-A, mutant Y294F, W295A, Y54F, F43H, H39Y 分子名称: (2~{S})-2-methylpentanedioic acid, Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M. 登録日 2017-06-19 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer. FEBS J., 284, 2017
6SHY	Structure of L320A/H321S double mutant of Rex8A from Paenibacillus barcinonensis 分子名称: 1,2-ETHANEDIOL, Reducing-end xylose-releasing exo-oligoxylanase Rex8A 著者 Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J. 登録日 2019-08-08 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structural analysis of the reducing-end xylose-releasing exo-oligoxylanase Rex8A from Paenibacillus barcinonensis BP-23 deciphers its molecular specificity. Febs J., 287, 2020
6SI5	T. cruzi FPPS in complex with 1-methyl-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carbonyl)pyridin-2(1H)-one 分子名称: 5-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-ylcarbonyl)-1-methyl-pyridin-2-one, Farnesyl diphosphate synthase, SULFATE ION 著者 Petrick, J.K, Muenzker, L, Schleberger, C, Cornaciu, I, Clavel, D, Marquez, J.A, Jahnke, W. 登録日 2019-08-08 公開日 2020-08-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019

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