5O9D

Crystal structure of R. ruber ADH-A, mutant Y294F, W295A, Y54F, F43H, H39Y

Summary for 5O9D

Entry DOI	10.2210/pdb5o9d/pdb
Descriptor	Alcohol dehydrogenase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	alcohol dehydrogenase mutant variant, nadh-dependent, zn2+-dependent, rossmann fold, oxidoreductase
Biological source	Rhodococcus sp. M8
Total number of polymer chains	4
Total formula weight	147637.08
Authors	Dobritzsch, D.,Maurer, D.,Hamnevik, E.,Enugala, T.R.,Widersten, M. (deposition date: 2017-06-19, release date: 2017-10-11, Last modification date: 2024-01-17)
Primary citation	Hamnevik, E.,Enugala, T.R.,Maurer, D.,Ntuku, S.,Oliveira, A.,Dobritzsch, D.,Widersten, M. Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer. FEBS J., 284:3895-3914, 2017 Cited by PubMed: 28963762 DOI: 10.1111/febs.14279 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation