PDB: 31489 件ウェブページステータス検索Chemie searchBIRD

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5NKZ	Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p 分子名称: Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa 著者 Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C. 登録日 2017-04-03 公開日 2018-01-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex. Biochem. Biophys. Res. Commun., 496, 2018
6SQ9	Crystal structure of M. tuberculosis InhA in complex with NAD+ and 3-hydroxynaphthalene-2-carboxylic acid 分子名称: 3-hydroxynaphthalene-2-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH], ... 著者 Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L. 登録日 2019-09-03 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors. J.Med.Chem., 63, 2020
5NL8	Pex4 of Hansenula Polymorpha 分子名称: Ubiquitin-conjugating enzyme E2-21 kDa 著者 Groves, M, Williams, C. 登録日 2017-04-04 公開日 2018-01-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex. Biochem. Biophys. Res. Commun., 496, 2018
6SQN	Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA 分子名称: RNA hairpin, U1 small nuclear ribonucleoprotein A 著者 Rosenbach, H, Span, I. 登録日 2019-09-04 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
5NDZ	Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ3451 at 3.6 angstrom resolution 分子名称: 2-(6-bromanyl-1,3-benzodioxol-5-yl)-~{N}-(4-cyanophenyl)-1-[(1~{S})-1-cyclohexylethyl]benzimidazole-5-carboxamide, Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2, SODIUM ION 著者 Cheng, R.K.Y, Fiez-Vandal, C, Schlenker, O, Edman, K, Aggeler, B, Brown, D.G, Brown, G, Cooke, R.M, Dumelin, C.E, Dore, A.S, Geschwindner, S, Grebner, C, Hermansson, N.-O, Jazayeri, A, Johansson, P, Leong, L, Prihandoko, R, Rappas, M, Soutter, H, Snijder, A, Sundstrom, L, Tehan, B, Thornton, P, Troast, D, Wiggin, G, Zhukov, A, Marshall, F.H, Dekker, N. 登録日 2017-03-09 公開日 2017-05-03 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural insight into allosteric modulation of protease-activated receptor 2. Nature, 545, 2017
5NE3	L2 class A serine-beta-lactamase complexed with avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase 著者 Hinchliffe, P, Calvopina, K, Spencer, J. 登録日 2017-03-09 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural/mechanistic insights into the efficacy of nonclassical beta-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates. Mol. Microbiol., 106, 2017
6SSQ	Crystal structure of RARbeta LBD in complex with LG 100754 分子名称: (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid, CITRATE ANION, GLYCEROL, ... 著者 le Maire, A, Teyssier, C, Germain, P, Bourguet, W. 登録日 2019-09-09 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations. Cells, 8, 2019
6ST0	Taurine ABC transporter substrate binding protein TauA from E. coli in complex with N-(2-Acetamido)-2-aminoethanesulfonic acid 分子名称: IODIDE ION, N-(2-acetamido)-2-aminoethanesulfonic acid, Taurine-binding periplasmic protein 著者 Beis, K, Qu, F. 登録日 2019-09-09 公開日 2019-12-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Desolvation of the substrate-binding protein TauA dictates ligand specificity for the alkanesulfonate ABC importer TauABC. Biochem.J., 476, 2019
5NLV	Brag2 Sec7-PH (390-763) 分子名称: IQ motif and SEC7 domain-containing protein 1 著者 Nawrotek, A, Cherfils, J. 登録日 2017-04-05 公開日 2017-09-27 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NF3	The fimbrial shaft protein Mfa1 from Porphyromonas gingivalis-C-terminal deletion 分子名称: ACETATE ION, CALCIUM ION, Minor fimbrium subunit Mfa1 著者 Hall, M, Hasegawa, Y, Persson, K, Yoshimura, F. 登録日 2017-03-13 公開日 2018-02-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural and functional characterization of shaft, anchor, and tip proteins of the Mfa1 fimbria from the periodontal pathogen Porphyromonas gingivalis. Sci Rep, 8, 2018
5NFY	SARS-CoV nsp10/nsp14 dynamic complex 分子名称: DI(HYDROXYETHYL)ETHER, Polyprotein 1ab, ZINC ION 著者 Ferron, F, Gluais, L, Vonrhein, C, Bricogne, G, Canard, B, Imbert, I. 登録日 2017-03-16 公開日 2018-01-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.382 Å) 主引用文献 Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6SXT	GH54 a-l-arabinofuranosidase soaked with aziridine inhibitor 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 McGregor, N.G.S, Davies, G.J, Nin-Hill, A, Rovira, C. 登録日 2019-09-26 公開日 2020-02-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.466 Å) 主引用文献 Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases. J.Am.Chem.Soc., 142, 2020
6STK	Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation 分子名称: ACETATE ION, C-C motif chemokine 5, GLYCEROL 著者 Ramirez-Escudero, M, Janssen, B.J.C. 登録日 2019-09-10 公開日 2020-09-02 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4. J.Biol.Chem., 295, 2020
5NGL	The endo-beta1,6-glucanase BT3312 分子名称: Glucosylceramidase, SODIUM ION, beta-D-glucopyranose-(1-6)-1-DEOXYNOJIRIMYCIN 著者 Basle, A, Temple, M, Cuskin, F, Lowe, E, Gilbert, H. 登録日 2017-03-17 公開日 2017-05-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A Bacteroidetes locus dedicated to fungal 1,6-beta-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-beta-glucanase. J. Biol. Chem., 292, 2017
5NHA	Crystal structure of xylose isomerase from Piromyces sp. E2 in complex with two Mn2+ ions and sorbitol 分子名称: MANGANESE (II) ION, SULFATE ION, Xylose isomerase, ... 著者 Rozeboom, H.J, Janssen, D.B. 登録日 2017-03-21 公開日 2017-11-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Metal Dependence of the Xylose Isomerase from Piromyces sp. E2 Explored by Activity Profiling and Protein Crystallography. Biochemistry, 56, 2017
5NMW	Crystal Structure of the pyrrolizidine alkaloid N-oxygenase from Zonocerus variegatus in complex with FAD 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase, MAGNESIUM ION 著者 Scheidig, A, Kubitza, C, Faust, A, Ober, D. 登録日 2017-04-07 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structure of pyrrolizidine alkaloid N-oxygenase from the grasshopper Zonocerus variegatus. Acta Crystallogr D Struct Biol, 74, 2018
5NPB	Crystal Structure of cjAgd31B (alpha-transglucosylase from Glycoside Hydrolase Family 31) in complex with alpha Cyclophellitol Cyclosulfate probe ME647 分子名称: OXALATE ION, Oligosaccharide 4-alpha-D-glucosyltransferase, SULFATE ION, ... 著者 Wu, L, Davies, G.J. 登録日 2017-04-16 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor. ACS Cent Sci, 3, 2017
5N1A	Crystal structure of Utp4 from Chaetomium thermophilum 分子名称: utp4 著者 Calvino, F.R, Ahmed, Y.L, Wild, K, Sinning, I. 登録日 2017-02-05 公開日 2017-06-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for 5'-ETS recognition by Utp4 at the early stages of ribosome biogenesis. PLoS ONE, 12, 2017
5NQ2	'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting IAYERMCNI 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ... 著者 Rizkallah, P.J, Tungatt, K, Sewell, A.K. 登録日 2017-04-19 公開日 2018-04-25 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
6SXS	GH54 a-l-arabinofuranosidase soaked with cyclic sulfate inhibitor 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 McGregor, N.G.S, Davies, G.J, Nin-Hill, A, Rovira, C. 登録日 2019-09-26 公開日 2020-02-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases. J.Am.Chem.Soc., 142, 2020
6SYD	Crystal structure of the lysozyme in presence of bromophenol blue at pH 5.5 分子名称: Lysozyme, SODIUM ION, bromophenol blue 著者 Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C. 登録日 2019-09-27 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Lysozyme crystals dyed with bromophenol blue: where has the dye gone? Acta Crystallogr D Struct Biol, 76, 2020
6SYL	STRUCTURE OF ESTER-HYDROLASE EH3 FROM THE METAGENOME OF MARINE SEDIMENTS AT MILAZZO HARBOR (SICILY, ITALY) COMPLEXED WITH A DERIVATIVE OF BUTYL 4-NITROPHENYL HEXYLPHOSPHONATE 分子名称: Esterase, butoxy(hexyl)phosphinic acid 著者 Cea-Rama, I, Sanz-Aparicio, J. 登録日 2019-09-30 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment. Acs Nano, 14, 2020
5NQN	CU(I)-CSP3 (COPPER STORAGE PROTEIN 3) FROM METHYLOSINUS 分子名称: COPPER (I) ION, CSP3, SODIUM ION 著者 Basle, A, Platsaki, S, Dennison, C. 登録日 2017-04-20 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Visualizing Biological Copper Storage: The Importance of Thiolate-Coordinated Tetranuclear Clusters. Angew. Chem. Int. Ed. Engl., 56, 2017
6SZM	Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2009 分子名称: 1,2-ETHANEDIOL, 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine, AMMONIUM ION, ... 著者 Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. 登録日 2019-10-02 公開日 2019-10-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
5MZE	Crystal structure of mouse MTH1 with 8-oxo-dGTP 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, COPPER (II) ION, ... 著者 Narwal, M, Jemth, A.-S, Helleday, T, Stenmark, P. 登録日 2017-01-31 公開日 2018-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry, 57, 2018

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