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2XKS
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Prion-like conversion during amyloid formation at atomic resolution
分子名称: BETA-2-MICROGLOBULIN
著者Eichner, T, Kalverda, A.P, Thompson, G.S, Radford, S.E, Homans, S.W.
登録日2010-07-12
公開日2011-02-16
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献Conformational Conversion During Amyloid Formation at Atomic Resolution.
Mol.Cell, 41, 2011
2PQK
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X-ray crystal structure of human Mcl-1 in complex with Bim BH3
分子名称: Bim BH3 peptide, Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ...
著者Bare, E, Grant, R.A, Keating, A.E.
登録日2007-05-02
公開日2007-06-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
2PXR
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BU of 2pxr by Molmil
Crystal Structure of HIV-1 CA146 in the Presence of CAP-1
分子名称: CHLORIDE ION, Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION
著者Kelly, B.N.
登録日2007-05-14
公開日2007-09-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein.
J.Mol.Biol., 373, 2007
2PRH
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BU of 2prh by Molmil
The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
分子名称: 6-CHLORO-2-(2'-FLUOROBIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Dihydroorotate dehydrogenase, ...
著者Walse, B, Dufe, V.T, Al-Karadaghi, S.
登録日2007-05-04
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites
Biochemistry, 47, 2008
2PU1
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Crystal Structure of the T. brucei enolase complexed with Fluoro-phosphonoacetohydroxamate (FPAH)
分子名称: 1,2-ETHANEDIOL, Enolase, ZINC ION, ...
著者Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
登録日2007-05-08
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
2Q0M
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Tricarbonylmanganese(I)-lysozyme complex : a structurally characterized organometallic protein
分子名称: CARBON MONOXIDE, CHLORIDE ION, Lysozyme C, ...
著者Razavet, M, Artero, V, Cavazza, C, Oudart, Y, Fontecilla-Camps, J.C, Fontecave, M.
登録日2007-05-22
公開日2007-12-11
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tricarbonylmanganese(I)-lysozyme complex: a structurally characterized organometallic protein.
Chem.Commun.(Camb.), 2007
2H6V
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BU of 2h6v by Molmil
Spectroscopic and structural study of the heterotropic linkage between halide and proton ion binding to GFP proteins- E2(GFP) APO FORM
分子名称: Green fluorescent protein, SODIUM ION
著者Garau, G.
登録日2006-06-01
公開日2007-05-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Spectroscopic and Structural Study of Proton and Halide Ion Cooperative Binding to GFP
Biophys.J., 93, 2007
2PS8
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Y295F Trichodiene Synthase: Complex With Mg and Pyrophosphate
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
著者Vedula, L.S, Cane, D.E, Christianson, D.W.
登録日2007-05-04
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
2HFF
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Crystal structure of CB2 Fab
分子名称: CB2 Fab, heavy chain, light chain
著者Hymowitz, S.G.
登録日2006-06-23
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood, 108, 2006
2Q59
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Crystal Structure of PPARgamma LBD bound to full agonist MRL20
分子名称: (2S)-2-(2-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID, Peroxisome Proliferator-Activated Receptor gamma
著者Bruning, J.B, Nettles, K.W.
登録日2007-05-31
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure, 15, 2007
2PTL
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BU of 2ptl by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN-BINDING DOMAIN OF PROTEIN L. COMPARISON WITH THE IGG-BINDING DOMAINS OF PROTEIN G
分子名称: PROTEIN L
著者Wikstroem, M, Drakenberg, T, Forsen, S, Sjoebring, U, Bjoerck, L.
登録日1994-08-12
公開日1994-10-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G.
Biochemistry, 33, 1994
2PVG
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Crystal srtucture of the binary complex between ferredoxin and ferredoxin:thioredoxin reductase
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ...
著者Dai, S.
登録日2007-05-09
公開日2007-07-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Nature, 448, 2007
2PVO
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Crystal srtucture of the ternary complex between thioredoxin f, ferredoxin, and ferredoxin: thioredoxin reductase
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ...
著者Dai, S.
登録日2007-05-09
公開日2007-07-10
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Nature, 448, 2007
2HFD
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NMR structure of protein Hydrogenase-1 operon protein hyaE from Escherichia coli: Northeast Structural Genomics Consortium Target ER415
分子名称: Hydrogenase-1 operon protein hyaE
著者Singarapu, K.K, Liu, G, Eletsky, A, Parish, D, Atreya, H.S, Xu, D, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2006-06-23
公開日2006-08-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif.
J.STRUCT.FUNCT.GENOM., 9, 2008
2Q9D
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Structure of spin-labeled T4 lysozyme mutant A41R1
分子名称: BETA-MERCAPTOETHANOL, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L.
登録日2007-06-12
公開日2007-06-26
最終更新日2023-08-30
実験手法EPR (1.4 Å), X-RAY DIFFRACTION
主引用文献Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme.
Protein Sci., 17, 2008
2GP7
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Estrogen Related Receptor-gamma ligand binding domain
分子名称: CALCIUM ION, Estrogen-related receptor gamma
著者Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
登録日2006-04-17
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
2GQ7
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Crystal structure of an RNA racemate
分子名称: CALCIUM ION, GLYCEROL, RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), ...
著者Rypniewski, W, Vallazza, M, Perbandt, M, Klussmann, S, Betzel, C, Erdmann, V.A.
登録日2006-04-20
公開日2006-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The first crystal structure of an RNA racemate.
Acta Crystallogr.,Sect.D, 62, 2006
2F6N
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Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the free form
分子名称: ZINC ION, bromodomain PHD finger transcription factor
著者Li, H, Patel, D.J.
登録日2005-11-29
公開日2006-07-11
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2H2W
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Crystal structure of Homoserine O-succinyltransferase (EC 2.3.1.46) (Homoserine O-transsuccinylase) (HTS) (tm0881) from THERMOTOGA MARITIMA at 2.52 A resolution
分子名称: Homoserine O-succinyltransferase
著者Joint Center for Structural Genomics (JCSG)
登録日2006-05-19
公開日2006-07-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Crystal structure of Homoserine O-succinyltransferase (EC 2.3.1.46) (Homoserine O-transsuccinylase) (HTS) (tm0881) from THERMOTOGA MARITIMA at 2.52 A resolution
To be published
2NBW
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Solution structure of the Rpn1 T1 site with the Rad23 UBL domain
分子名称: 26S proteasome regulatory subunit RPN1, UV excision repair protein RAD23
著者Chen, X, Walters, K.J.
登録日2016-03-14
公開日2016-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
2H0K
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Crystal Structure of a Mutant of Rat Annexin A5
分子名称: Annexin A5, CALCIUM ION
著者Granier, T, Langlois D'Estaintot, B, Gallois, B, Tessier, B, Brisson, A.
登録日2006-05-15
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair.
Nat Commun, 2, 2011
4COC
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HIV-1 capsid C-terminal domain mutant (Y169L)
分子名称: CAPSID PROTEIN P24, SULFATE ION
著者Bharat, T.A.M, Castillo-Menendez, L.R, Hagen, W.J.H, Lux, V, Igonet, S, Schorb, M, Schur, F.K.M, Krausslich, H.-G, Briggs, J.A.G.
登録日2014-01-28
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Cryo-Electron Microscopy of Tubular Arrays of HIV-1 Gag Resolves Structures Essential for Immature Virus Assembly.
Proc.Natl.Acad.Sci.USA, 111, 2014
2H1E
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Tandem chromodomains of budding yeast CHD1
分子名称: Chromo domain protein 1
著者Flanagan IV, J.F, Khorasanizadeh, S.
登録日2006-05-16
公開日2007-03-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Implications of Evolutionary Differences in CHD Double Chromodomains.
J.Mol.Biol., 369, 2007
2NAD
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HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE
分子名称: AZIDE ION, NAD-DEPENDENT FORMATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Lamzin, V.S, Dauter, Z, Popov, V.O, Harutyunyan, E.H, Wilson, K.S.
登録日1994-07-06
公開日1995-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献High resolution structures of holo and apo formate dehydrogenase.
J.Mol.Biol., 236, 1994
2NO5
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Crystal Structure analysis of a Dehalogenase with intermediate complex
分子名称: (2S)-2-CHLOROPROPANOIC ACID, (S)-2-haloacid dehalogenase IVA, CHLORIDE ION, ...
著者Schmidberger, J.W, Wilce, M.C.J.
登録日2006-10-24
公開日2007-09-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4
J.Mol.Biol., 368, 2007

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