PDB: 98546 件ウェブページステータス検索Chemie searchBIRD

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8EJV	The crystal structure of Pseudomonas putida PcaR in complex with succinate 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... 著者 Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. 登録日 2022-09-19 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 The crystal structure of Pseudomonas putida PcaR in complex with succinate To Be Published
8EJU	The crystal structure of Pseudomonas putida PcaR 分子名称: CHLORIDE ION, PHOSPHATE ION, Transcription regulatory protein (Pca regulon), ... 著者 Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. 登録日 2022-09-19 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The crystal structure of Pseudomonas putida PcaR To Be Published
8FZK	Dimeric human importin alpha subunit 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION 著者 Donnelly, C.M, Stewart, M, Forwood, J.K. 登録日 2023-01-29 公開日 2023-02-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dimeric human importin alpha subunit To Be Published
8FDP	The native structure of a dodecamer: 5'-CGCAAATTTGCG-3 分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3') 著者 Ogbonna, E, Wilson, W.D. 登録日 2022-12-04 公開日 2023-02-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. Acs Bio Med Chem Au, 3, 2023
6NOG	Poised-state Dot1L bound to the H2B-Ubiquitinated nucleosome 分子名称: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... 著者 Worden, E.J, Hoffmann, N.A, Wolberger, C. 登録日 2019-01-16 公開日 2019-02-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L. Cell, 176, 2019
8PCH	CRYSTAL STRUCTURE OF PORCINE CATHEPSIN H DETERMINED AT 2.1 ANGSTROM RESOLUTION: LOCATION OF THE MINI-CHAIN C-TERMINAL CARBOXYL GROUP DEFINES CATHEPSIN H AMINOPEPTIDASE FUNCTION 分子名称: CATHEPSIN H, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Guncar, G, Podobnik, M, Pungercar, J, Strukelj, B, Turk, V, Turk, D. 登録日 1997-11-07 公開日 1998-12-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function. Structure, 6, 1998
8PI3	Cathepsin S Y132D mutant in complex with NNPI-C10 inhibitor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CADMIUM ION, ... 著者 Petruzzella, A, Lau, K, Pojer, F, Oricchio, E. 登録日 2023-06-21 公開日 2024-06-05 最終更新日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. Nat.Chem.Biol., 20, 2024
6I0U	Crystal structure of DmTailor in complex with U6 RNA 分子名称: MAGNESIUM ION, RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor 著者 Kroupova, A, Ivascu, A, Jinek, M. 登録日 2018-10-26 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
4JL0	Crystal structure of PcrH in complex with the chaperone binding region of PopB 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PopB, Regulatory protein PcrH 著者 Discola, K.F, Forster, A, Simorre, J.P, Attree, I, Dessen, A, Job, V. 登録日 2013-03-12 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa. J.Biol.Chem., 289, 2014
5XDO	Crystal structure of human voltage-dependent anion channel 1 (hVDAC1) in C222 space group 分子名称: HEXANE, N-OCTANE, PENTANE, ... 著者 Hosaka, T, Kimura-Someya, T, Shirouzu, M. 登録日 2017-03-28 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structural characterization reveals novel oligomeric interactions of human voltage-dependent anion channel 1 Protein Sci., 26, 2017
8A3Y	Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. 登録日 2022-06-09 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
8RND	Cathepsin S in complex with NNPI-C10 inhibitor 分子名称: 1,2-ETHANEDIOL, Cathepsin S, DI(HYDROXYETHYL)ETHER, ... 著者 Petruzzella, A, Lau, K, Pojer, F, Oricchio, E. 登録日 2024-01-09 公開日 2024-06-05 最終更新日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. Nat.Chem.Biol., 20, 2024
7ZS9	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
6I0S	Crystal structure of DmTailor in complex with UMPNPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, Terminal uridylyltransferase Tailor 著者 Kroupova, A, Ivascu, A, Jinek, M. 登録日 2018-10-26 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
6I0T	Crystal structure of DmTailor in complex with GpU 分子名称: RNA (5'-R(*GP*U)-3'), Terminal uridylyltransferase Tailor 著者 Kroupova, A, Ivascu, A, Jinek, M. 登録日 2018-10-26 公開日 2018-12-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
8FJ8	Crystal structure of Mn(2+),Ca(2+)-S100B 分子名称: CALCIUM ION, MANGANESE (II) ION, Protein S100-B 著者 Hunter, D.A. 登録日 2022-12-19 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural insights into ions binding to S100A1 versus S100B To Be Published
8OZA	Human cathepsin L in complex with covalently bound CA-074 methyl ester 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cathepsin L, ... 著者 Falke, S, Lieske, J, Guenther, S, Ewert, W, Reinke, P.Y.A, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2023-05-08 公開日 2023-07-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
6O96	Dot1L bound to the H2BK120 Ubiquitinated nucleosome 分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ... 著者 Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Vasilyev, N, Chen, R, Nudler, E, Armache, J.-P, Armache, K.-J. 登録日 2019-03-13 公開日 2019-04-24 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination. Mol.Cell, 74, 2019
6N6X	OXA-23 mutant F110A/M221A neutral pH form imipenem complex 分子名称: Beta-lactamase oxa23, Imipenem, SULFATE ION 著者 Smith, C.A, Vakulenko, S.B. 登録日 2018-11-27 公開日 2018-12-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63, 2019
6N6U	OXA-23 mutant F110A/M221A low pH form imipenem complex 分子名称: Beta-lactamase, Imipenem 著者 Smith, C.A, Vakulenko, S.B. 登録日 2018-11-27 公開日 2018-12-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63, 2019
8OFA	Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK) 分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide, ... 著者 Falke, S, Lieske, J, Guenther, S, Ewert, W, Reinke, P.Y.A, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2023-03-14 公開日 2023-11-29 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
6NE3	Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (156-MER), Histone H2A type 1, ... 著者 Armache, J.-P, Gamarra, N, Johnson, S.L, Leonard, J.D, Wu, S, Narlikar, G.N, Cheng, Y. 登録日 2018-12-16 公開日 2019-07-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome. Elife, 8, 2019
4LHW	Crystal structure of Rab8 in its active GppNHp-bound form 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
4LI0	Crystal structure of GDP-bound Rab8:GRAB 分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide exchange factor for Rab-3A, Ras-related protein Rab-8A 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
4LHX	Crystal structure of nucleotide-free Rab8:Rabin8 分子名称: Rab-3A-interacting protein, Ras-related protein Rab-8A, SULFATE ION 著者 Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. 登録日 2013-07-01 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013

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