PDB: 60814 件ウェブページステータス検索Chemie searchBIRD

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4WWU	Structure of Mex67:Mtr2 分子名称: ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2 著者 Aibara, S, Valkov, E, Stewart, M. 登録日 2014-11-12 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface. Nucleic Acids Res., 43, 2015
8TCG	Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... 著者 Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. 登録日 2023-06-30 公開日 2023-09-27 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
4WY5	Structural analysis of two fungal esterases from Rhizomucor miehei explaining their substrate specificity 分子名称: Esterase, SULFATE ION 著者 Qin, Z, Yang, S, Duan, X, Yan, Q, Jiang, Z. 登録日 2014-11-15 公開日 2015-07-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structural insights into the substrate specificity of two esterases from the thermophilic Rhizomucor miehei J.Lipid Res., 56, 2015
6MO9	N-terminal bromodomain of human BRD2 in complex with N-cyclopentyl-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide inhibitor 分子名称: Bromodomain-containing protein 2, N-cyclopentyl-7-(3,5-dimethyl-1,2-oxazol-4-yl)quinoline-5-sulfonamide 著者 Lansdon, E.B, Newby, Z.E.R. 登録日 2018-10-04 公開日 2019-01-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor. Bioorg. Med. Chem., 27, 2019
4X8S	FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 4-BROMO-2-METHOXYPHENOL 分子名称: 4-bromo-2-methoxyphenol, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Wei, A. 登録日 2014-12-10 公開日 2015-03-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening. J.Med.Chem., 58, 2015
8GJ8	RAD51C C-terminal domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAD51C 著者 Arvai, A.S, Tainer, J.A, Williams, G. 登録日 2023-03-15 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. Nat Commun, 14, 2023
4WZB	Crystal Structure of MgAMPPCP-bound Av2-Av1 complex 分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (II) ION, FE(8)-S(7) CLUSTER, ... 著者 Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. 登録日 2014-11-19 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nitrogenase complexes: multiple docking sites for a nucleotide switch protein. Science, 309, 2005
2W5K	RNASE A-NADPH COMPLEX 分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC 著者 Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R. 登録日 2008-12-10 公開日 2009-02-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study. Biopolymers, 91, 2009
4X2S	Crystal structure of 276S/M395R-GltPh in inward-facing conformation 分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION 著者 Akyuz, N, Boudker, O. 登録日 2014-11-26 公開日 2015-02-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.21 Å) 主引用文献 Transport domain unlocking sets the uptake rate of an aspartate transporter. Nature, 518, 2015
6MW2	cyclo-Mle-Phe-Mle-D-Phe. D-Phe analogue of pseudoxylallemycin A. 分子名称: pseudoxylallemycin A 著者 Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J. 登録日 2018-10-29 公開日 2019-09-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (0.77 Å) 主引用文献 Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A. Org.Biomol.Chem., 17, 2019
7P9M	BrxU, GmrSD-family Type IV restriction enzyme 分子名称: CHLORIDE ION, DUF262 domain-containing protein, SULFATE ION 著者 Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R. 登録日 2021-07-27 公開日 2021-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses. Nucleic Acids Res., 49, 2021
2BB2	X-RAY ANALYSIS OF BETA B2-CRYSTALLIN AND EVOLUTION OF OLIGOMERIC LENS PROTEINS 分子名称: BETA B2-CRYSTALLIN, BETA-MERCAPTOETHANOL 著者 Bax, B, Lapatto, R, Nalini, V, Driessen, H, Lindley, P.F, Mahadevan, D, Blundell, T.L, Slingsby, C. 登録日 1992-09-21 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray analysis of beta B2-crystallin and evolution of oligomeric lens proteins. Nature, 347, 1990
7SGJ	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711 分子名称: 1,2-ETHANEDIOL, 4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide, DI(HYDROXYETHYL)ETHER, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2021-10-05 公開日 2022-10-05 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
7PRP	Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in apo form 分子名称: FORMIC ACID, Heat-labile enterotoxin IIA, B chain, ... 著者 Varrot, A. 登録日 2021-09-22 公開日 2021-12-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc. Glycobiology, 32, 2022
8GOS	Crystal structure of fluorescent protein RasM 分子名称: RasM 著者 Adachi, M, Kagotani, Y, Shimizu, R. 登録日 2022-08-25 公開日 2023-09-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.01 Å) 主引用文献 Beat-frequency-resolved two-dimensional electronic spectroscopy: disentangling vibrational coherences in artificial fluorescent proteins with sub-10-fs visible laser pulses. Opt Express, 31, 2023
7SGI	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Inhibitor 14 分子名称: 5-[(2-anilino-2-oxoethyl)(methyl)amino]-N-hydroxypentanamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2021-10-05 公開日 2022-10-05 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc., 144, 2022
4WNN	SPT16-H2A-H2B FACT HISTONE Complex 分子名称: Histone H2A.1, Histone H2B.1, PHOSPHATE ION, ... 著者 Kemble, D.J, Hill, C.P, Whitby, F.G, Formosa, T, McCullough, L.L. 登録日 2014-10-13 公開日 2015-10-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol.Cell, 60, 2015
4WNZ	Crystal structure of Pyrococcus furiosus Cmr4 (Cas7) 分子名称: CRISPR system Cmr subunit Cmr4 著者 Zhu, X, Ye, K. 登録日 2014-10-15 公開日 2015-01-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex Nucleic Acids Res., 43, 2015
4WOB	Proteinase-K Pre-Surface Acoustic Wave 分子名称: Proteinase K, SULFATE ION 著者 French, J.B. 登録日 2014-10-15 公開日 2015-02-18 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. Small, 11, 2015
6N3J	MicroED Structure of the CTD-SP1 fragment of HIV-1 Gag 分子名称: CTD-SP1 fragment of HIV-1 Gag 著者 Purdy, M.D, Shi, D, Hattne, J, Chrustowicz, J. 登録日 2018-11-15 公開日 2018-12-12 最終更新日 2023-10-11 実験手法 ELECTRON CRYSTALLOGRAPHY (3 Å) 主引用文献 MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4WK2	Metal Ion and Ligand Binding of Integrin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Xia, W, Springer, T.A. 登録日 2014-10-01 公開日 2014-12-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Metal ion and ligand binding of integrin alpha 5 beta 1. Proc.Natl.Acad.Sci.USA, 111, 2014
8W31	Crystal structure of parkin (R0RB):2pUb with activator compound 分子名称: (S)-1-(6-benzyl-3-(4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)ethan-1-one, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... 著者 Sauve, V, Gehring, K. 登録日 2024-02-21 公開日 2024-08-21 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Activation of parkin by a molecular glue. Nat Commun, 15, 2024
8WJQ	Cryo-EM structure of URAT1(R477S)-Urate complex 分子名称: Solute carrier family 22 member 12, URIC ACID 著者 Qian, H.W, He, J.J. 登録日 2023-09-26 公開日 2024-08-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis for the transport and substrate selection of human urate transporter 1. Cell Rep, 43, 2024
8WJH	Cryo-EM structure of OAT4 分子名称: CHLORIDE ION, Solute carrier family 22 member 11 著者 Qian, H.W, He, J.J. 登録日 2023-09-26 公開日 2024-08-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for the transport and substrate selection of human urate transporter 1. Cell Rep, 43, 2024
8WJG	Cryo-EM structure of URAT1(R477S) 分子名称: Solute carrier family 22 member 12 著者 Qian, H.W, He, J.J. 登録日 2023-09-25 公開日 2024-08-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for the transport and substrate selection of human urate transporter 1. Cell Rep, 43, 2024

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