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2VZ8
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Crystal Structure of Mammalian Fatty Acid Synthase
分子名称: FATTY ACID SYNTHASE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.219 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
7JQ2
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Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI5
分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-L-valyl-3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide
著者Yang, K, Liu, W.
登録日2020-08-10
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Chemmedchem, 16, 2021
1N28
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BU of 1n28 by Molmil
Crystal structure of the H48Q mutant of human group IIA phospholipase A2
分子名称: CALCIUM ION, Phospholipase A2, membrane associated
著者Edwards, S.H, Thompson, D, Baker, S.F, Wood, S.P, Wilton, D.C.
登録日2002-10-22
公開日2003-10-28
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism
Biochemistry, 41, 2002
2W4L
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BU of 2w4l by Molmil
Human dCMP deaminase
分子名称: CHLORIDE ION, DEOXYCYTIDYLATE DEAMINASE, ZINC ION
著者Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schuler, H, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Nordlund, P.
登録日2008-11-28
公開日2009-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of Human Dcmp Deaminase
To be Published
4LRO
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BU of 4lro by Molmil
Crystal structure of spermidine inhibited Ribosome inactivating protein from Momordica balsamina
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SPERMIDINE, ...
著者Yamini, S, Pandey, S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-07-20
公開日2013-08-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of spermidine inhibited Ribosome inactivating protein from Momordica balsamina
To be Published
3FY1
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BU of 3fy1 by Molmil
The Acidic Mammalian Chitinase catalytic domain in complex with methylallosamidin
分子名称: 2-acetamido-2-deoxy-6-O-methyl-alpha-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, Acidic mammalian chitinase
著者Olland, A.M.
登録日2009-01-21
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
Protein Sci., 18, 2009
4LHJ
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BU of 4lhj by Molmil
Ricin A chain bound to camelid nanobody (VHH5)
分子名称: CHLORIDE ION, Camelid antibody, Ricin
著者Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N.
登録日2013-07-01
公開日2014-06-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LLL
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BU of 4lll by Molmil
Crystal structure of S. aureus MepR-DNA complex
分子名称: MepR, Palindromized mepR operator sequence
著者Birukou, I, Brennan, R.G.
登録日2013-07-09
公開日2014-05-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.036 Å)
主引用文献Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.
Nucleic Acids Res., 42, 2014
3GA3
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BU of 3ga3 by Molmil
Crystal structure of the C-terminal domain of human MDA5
分子名称: Interferon-induced helicase C domain-containing protein 1, MDA5, ZINC ION
著者Li, P.
登録日2009-02-16
公開日2009-02-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of the C-terminal domain of human MDA5
To be Published
7QLN
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BU of 7qln by Molmil
rsKiiro pump probe structure by TR-SFX
分子名称: rsKiiro
著者van Thor, J.J.
登録日2021-12-20
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Optical control of ultrafast structural dynamics in a fluorescent protein.
Nat.Chem., 15, 2023
4FRB
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BU of 4frb by Molmil
Crystal Structure of ABBA+UDP+Gal at pH 8.0 with MPD as the cryoprotectant
分子名称: Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
著者Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V.
登録日2012-06-26
公開日2013-12-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state.
Glycobiology, 24, 2014
2W0O
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BU of 2w0o by Molmil
Horse spleen apoferritin
分子名称: CADMIUM ION, FERRITIN LIGHT CHAIN, SULFATE ION
著者De Val, N, Declercq, J.P.
登録日2008-08-20
公開日2008-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of Haemin Demetallation by L-Chain Apoferritins
J.Inorg.Biochem., 112, 2012
8X5N
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BU of 8x5n by Molmil
Tetramer Gabija with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ...
著者Li, J, Wang, Z, Wang, L.
登録日2023-11-17
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8VKR
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BU of 8vkr by Molmil
CW Flagellar Switch Complex with extra density - FliF, FliG, FliM, and FliN forming the C-ring from Salmonella
分子名称: Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ...
著者Singh, P.K, Iverson, T.M.
登録日2024-01-09
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis for rotation and directional switching by the combined MS- and C-rings of bacterial flagella.
To Be Published
4F93
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BU of 4f93 by Molmil
Brr2 Helicase Region S1087L, Mg-ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C.
登録日2012-05-18
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
1N4S
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BU of 1n4s by Molmil
Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product
分子名称: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
5GW4
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BU of 5gw4 by Molmil
Structure of Yeast NPP-TRiC
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Zang, Y, Jin, M, Wang, H, Cong, Y.
登録日2016-09-08
公開日2016-10-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
2W2P
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BU of 2w2p by Molmil
PCSK9-deltaC D374A mutant bound to WT EGF-A of LDLR
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
著者Bottomley, M.J, Cirillo, A, Orsatti, L, Ruggeri, L, Fisher, T.S, Santoro, J.C, Cummings, R.T, Cubbon, R.M, Lo Surdo, P, Calzetta, A, Noto, A, Baysarowich, J, Mattu, M, Talamo, F, De Francesco, R, Sparrow, C.P, Sitlani, A, Carfi, A.
登録日2008-11-03
公開日2008-11-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
J.Biol.Chem., 284, 2009
8VKQ
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BU of 8vkq by Molmil
CW Flagellar Switch Complex - FliF, FliG, FliM, and FliN forming the C-ring from Salmonella
分子名称: Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ...
著者Singh, P.K, Iverson, T.M.
登録日2024-01-09
公開日2024-02-28
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis for rotation and directional switching by the combined MS- and C-rings of bacterial flagella.
To Be Published
5A16
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BU of 5a16 by Molmil
Crystal structure of Fab4201 raised against Human Erythrocyte Anion Exchanger 1
分子名称: FAB4201 HEAVY CHAIN
著者Arakawa, T, Kobayashi-Yugiri, T, Alguel, Y, Weyand, S, Iwanari, H, Hatae, H, Iwata, M, Abe, Y, Hino, T, Ikeda-Suno, C, Kuma, H, Kang, D, Murata, T, Hamakubo, T, Cameron, A, Kobayashi, T, Hamasaki, N, Iwata, S.
登録日2015-04-28
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015
7RB2
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BU of 7rb2 by Molmil
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU in BIS-Tris pH 6.0
分子名称: Uridylate-specific endoribonuclease
著者Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G.
登録日2021-07-05
公開日2021-07-14
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 51, 2023
2VRJ
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BU of 2vrj by Molmil
Beta-glucosidase from Thermotoga maritima in complex with N-octyl-5- deoxy-6-oxa-N-(thio)carbamoylcalystegine
分子名称: (1S,2R,3S,4R,5R)-2,3,4-trihydroxy-N-octyl-6-oxa-8-azabicyclo[3.2.1]octane-8-carbothioamide, ACETATE ION, BETA-GLUCOSIDASE A, ...
著者Aguilar, M, Gloster, T.M, Garcia-Moreno, M.I, Ortiz Mellet, C, Davies, G.J, Llebaria, A, Casas, J, Egido-Gabas, M, Garcia Fernandez, J.M.
登録日2008-04-09
公開日2008-10-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis for Beta-Glucosidase Inhibition by Ring-Modified Calystegine Analogues.
Chembiochem, 9, 2008
8WGV
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BU of 8wgv by Molmil
BA.2(S375) Spike (S6P)/hACE2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Wei, X, Zhang, Z.
登録日2023-09-22
公開日2024-02-28
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
Nat.Immunol., 25, 2024
7K11
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CryoEM structure of inactivated-form FATKIN domain of DNA-PK
分子名称: DNA-dependent protein kinase catalytic subunit
著者Chen, X, Gellert, M, Yang, W.
登録日2020-09-06
公開日2021-01-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure of an activated DNA-PK and its implications for NHEJ.
Mol.Cell, 81, 2021
4LNV
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Crystal Structure of TEP1s
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thioester-containing protein I
著者Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
登録日2013-07-12
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Plos Pathog., 8, 2012

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