2MZL
| The Solution Structure of the Magnesium-bound Conantokin-G Mutant | 分子名称: | Conantokin-R1-B | 著者 | Kunda, S, Yuan, Y, Balsara, R.D, Zajicek, J, Castellino, F.J. | 登録日 | 2015-02-14 | 公開日 | 2015-06-17 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors. J.Biol.Chem., 290, 2015
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2A98
| Crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate 3-kinase C | 著者 | Hallberg, B.M, Ogg, D, Ehn, M, Graslund, S, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Persson, C, Sagemark, J, Schuler, H, Stenmark, P, Thorsell, A.-G, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-11 | 公開日 | 2005-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C To be Published
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2LQ3
| Solution NMR Structure of syc0711_d from Synechococcus sp., Northeast Structural Genomics Consortium (NESG) Target SnR212 | 分子名称: | Uncharacterized protein | 著者 | Mills, J.L, Sathyamoorthy, B, Pulavarti, S, Janjua, H, Kohan, E, Wang, D, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-02-23 | 公開日 | 2012-03-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of syc0711_d from Synechococcus sp., Northeast Structural Genomics Consortium (NESG) Target SnR212 To be Published
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5WIU
| Structure of the human D4 Dopamine receptor in complex with Nemonapride | 分子名称: | D(4) dopamine receptor, soluble cytochrome b562 chimera, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wacker, D, Wang, S, Levit, A, Che, T, Betz, R.M, McCorvy, J.D, Venkatakrishnan, A.J, Huang, X.-P, Dror, R.O, Shoichet, B.K, Roth, B.L. | 登録日 | 2017-07-20 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.962 Å) | 主引用文献 | D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science, 358, 2017
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1EHI
| D-ALANINE:D-LACTATE LIGASE (LMDDL2) OF VANCOMYCIN-RESISTANT LEUCONOSTOC MESENTEROIDES | 分子名称: | 1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC ACID, ADENOSINE-5'-DIPHOSPHATE, D-ALANINE:D-LACTATE LIGASE, ... | 著者 | Kuzin, A.P, Sun, T, Jorczak-Baillass, J, Healy, V.L, Walsh, C.T, Knox, J.R. | 登録日 | 2000-02-21 | 公開日 | 2000-05-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides. Structure Fold.Des., 8, 2000
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4P1J
| Crystal structure of wild type Hypocrea jecorina Cel7a in a hexagonal crystal form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Exoglucanase 1, SAMARIUM (III) ION, ... | 著者 | Bodenheimer, A.B, Cuneo, M.J, Swartz, P.D, Myles, D.A, Meilleur, F. | 登録日 | 2014-02-26 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Crystal structure of wild type Hypocrea jecorina Cel7a in a hexagonal crystal form To Be Published
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5I1O
| Villin headpiece subdomain with a Gln26 to ACPC substitution | 分子名称: | D-Villin headpiece subdomain, Villin-1 | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | 登録日 | 2016-02-05 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.348 Å) | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. J.Am.Chem.Soc., 138, 2016
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5I1S
| Villin headpiece subdomain with a Lys30 to APC substitution | 分子名称: | D-Villin headpiece subdomain, Villin-1 | 著者 | Kreitler, D.F, Mortenson, D.E, Gellman, S.H, Forest, K.T. | 登録日 | 2016-02-05 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. J.Am.Chem.Soc., 138, 2016
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6CTY
| Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and malate at 2.4 A resolution | 分子名称: | D-MALATE, Dihydroorotase, ZINC ION | 著者 | Lipowska, J, Shabalin, I.G, Winsor, J, Woinska, M, Cooper, D.R, Kwon, K, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-03-23 | 公開日 | 2018-04-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae. Int.J.Biol.Macromol., 136, 2019
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4PGL
| Crystal structure of engineered D-tagatose 3-epimerase PcDTE-ILS6 | 分子名称: | D-tagatose 3-epimerase, L-sorbose, L-tagatose, ... | 著者 | Hee, C.S, Bosshart, A, Schirmer, T. | 登録日 | 2014-05-02 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates. Chembiochem, 16, 2015
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4GJJ
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3DC2
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1EI5
| CRYSTAL STRUCTURE OF A D-AMINOPEPTIDASE FROM OCHROBACTRUM ANTHROPI | 分子名称: | D-AMINOPEPTIDASE | 著者 | Bompard-Gilles, C, Remaut, H, Villeret, V, Prange, T, Fanuel, L, Joris, J, Frere, J.-M, Van Beeumen, J. | 登録日 | 2000-02-24 | 公開日 | 2000-10-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family. Structure Fold.Des., 8, 2000
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3MA0
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5XSJ
| XylFII-LytSN complex | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS, ... | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | 登録日 | 2017-06-14 | 公開日 | 2017-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XSS
| XylFII molecule | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, beta-D-xylopyranose | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | 登録日 | 2017-06-15 | 公開日 | 2017-08-02 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WIV
| Structure of the sodium-bound human D4 Dopamine receptor in complex with Nemonapride | 分子名称: | D(4) dopamine receptor, soluble cytochrome b562 chimera, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wacker, D, Wang, S, Levit, A, Che, T, Betz, R.M, McCorvy, J.D, Venkatakrishnan, A.J, Huang, X.-P, Dror, R.O, Shoichet, B.K, Roth, B.L. | 登録日 | 2017-07-20 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.143 Å) | 主引用文献 | D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science, 358, 2017
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5X6S
| Acetyl xylan esterase from Aspergillus awamori | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylxylan esterase A, ... | 著者 | Komiya, D, Koseki, T, Fushinobu, S. | 登録日 | 2017-02-23 | 公開日 | 2017-08-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure and Substrate Specificity Modification of Acetyl Xylan Esterase from Aspergillus luchuensis Appl. Environ. Microbiol., 83, 2017
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7NZO
| D-lyxose isomerasefrom the hyperthermophilic archaeon Thermofilum sp | 分子名称: | 1,2-ETHANEDIOL, D-lyxose/D-mannose family sugar isomerase, MANGANESE (II) ION | 著者 | De Rose, S.A, Isupov, M.N, Littlechild, J.A, Schoenheit, P. | 登録日 | 2021-03-24 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp. Front Bioeng Biotechnol, 9, 2021
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8H1L
| Crystal structure of glucose-2-epimerase in complex with D-Glucitol from Runella slithyformis Runsl_4512 | 分子名称: | N-acylglucosamine 2-epimerase, sorbitol | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | 登録日 | 2022-10-03 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis. Acta Crystallogr D Struct Biol, 79, 2023
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8H1N
| Crystal structure of glucose-2-epimerase mutant_D254A in complex with D-Glucitol from Runella slithyformis Runsl_4512 | 分子名称: | FORMIC ACID, N-acylglucosamine 2-epimerase, sorbitol | 著者 | Wang, H, Sun, X.M, Saburi, W, Yu, J, Yao, M. | 登録日 | 2022-10-03 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural insights into the substrate specificity and activity of a novel mannose 2-epimerase from Runella slithyformis. Acta Crystallogr D Struct Biol, 79, 2023
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5LVX
| Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator | 分子名称: | 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zheng, J, Chen, L, Skinner, O.S, Lansbury, P, Skerlj, R, Mrosek, M, Heunisch, U, Krapp, S, Weigand, S, Charrow, J, Schwake, M, Kelleher, N.L, Silverman, R.B, Krainc, D. | 登録日 | 2016-09-14 | 公開日 | 2017-10-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site. J. Am. Chem. Soc., 140, 2018
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6O93
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5MHP
| Novel Imidazo[1,2-a]pyridine Derivatives with Potent Autotaxin/ENPP2 Inhibitor Activity | 分子名称: | 2-[[2-ethyl-8-methyl-6-[4-[2-(3-oxidanylazetidin-1-yl)-2-oxidanylidene-ethyl]piperazin-1-yl]imidazo[1,2-a]pyridin-3-yl]-methyl-amino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Fleury, D, Mueller, I, Lamers, M, Triballeau, N, Mollat, P, Vercheval, L. | 登録日 | 2016-11-25 | 公開日 | 2017-08-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis. J. Med. Chem., 60, 2017
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7RDF
| Crystal structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase Y249F co-crystallized in the presence of D-arginine | 分子名称: | 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, FAD-dependent catabolic D-arginine dehydrogenase DauA, ... | 著者 | Reis, R.A.G, Iyer, A, Agniswamy, A, Weber, I.T, Gadda, G. | 登録日 | 2021-07-09 | 公開日 | 2021-12-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase. Arch.Biochem.Biophys., 715, 2021
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