PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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8VEI	De novo designed colic acid binder CHD_r1 分子名称: CHD_r1 著者 Bera, A.K, An, L, Baker, D. 登録日 2023-12-19 公開日 2024-07-17 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science, 385, 2024
6X0A	X-ray structure of a chimeric ParDE toxin-antitoxin complex from Mesorhizobium opportunistum 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Plasmid stabilization system, Putative addiction module antidote protein, ... 著者 Lite, T.L, Grant, R.A, Laub, M.T. 登録日 2020-05-15 公開日 2020-11-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library. Elife, 9, 2020
6VW9	C-terminal regulatory domain of the chloride transporter KCC-1 from C. elegans, proteolyzed during crystallization 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, K+/Cl-Cotransporter 著者 Zimanyi, C.M, Cheung, J. 登録日 2020-02-19 公開日 2020-07-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the Regulatory Cytosolic Domain of a Eukaryotic Potassium-Chloride Cotransporter. Structure, 28, 2020
6W44	Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4 分子名称: 5-[methyl-[(2-propoxypyridin-3-yl)methyl]amino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 著者 Ferguson, A.D. 登録日 2020-03-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
6W4C	Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5 分子名称: 5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 著者 Ferguson, A.D. 登録日 2020-03-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
4Y4U	Endothiapepsin in complex with fragment 14 分子名称: 1-(4-bromo-2-chlorophenyl)-3-methylthiourea, DI(HYDROXYETHYL)ETHER, Endothiapepsin, ... 著者 Radeva, N, Uehlein, M, Weiss, M.S, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.754 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4Y4Z	Endothiapepsin in complex with fragment 73 分子名称: (1Z)-N,N-diethylethanimidamide, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4Y58	Endothiapepsin in complex with fragment 260 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Wang, X, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library to be published
4Y5K	Endothiapepsin in complex with fragment 274 分子名称: (1S)-2-amino-1-(4-fluorophenyl)ethanol, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Wang, X, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.439 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library to be published
4YD5	Endothiapepsin in complex with fragment 236 分子名称: 1-(2-chloro-5-nitrophenyl)-N-methylmethanamine, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Stieler, M, Heine, A, Klebe, G. 登録日 2015-02-20 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.209 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4Y3H	Endothiapepsin in complex with fragment 189 分子名称: 2-(pyridin-3-yl)ethanamine, ACETATE ION, Endothiapepsin, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2015-02-10 公開日 2016-02-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library To Be Published
4KJZ	Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474) 分子名称: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2 著者 Eiler, D.R, Lin, J, Steitz, T.A. 登録日 2013-05-04 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases. Proc.Natl.Acad.Sci.USA, 110, 2013
6NL3	Solution structure of human Coa6 分子名称: Cytochrome c oxidase assembly factor 6 homolog 著者 Naik, M.T, Soma, S, Gohil, V. 登録日 2019-01-07 公開日 2019-11-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. Cell Rep, 29, 2019
7THE	Structure of RBD directed antibody DH1042 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 Fab Heavy Chain, DH1042 Fab Light Chain, ... 著者 May, A.J, Manne, K, Acharya, P. 登録日 2022-01-10 公開日 2022-02-16 最終更新日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
6NZC	Crystal structure of E. coli fumarase C N326A variant with closed SS Loop at 1.40 angstrom resolution 分子名称: CITRIC ACID, Fumarate hydratase class II 著者 Weaver, T.M, May, J.F, Bhattacharyya, B. 登録日 2019-02-13 公開日 2019-09-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.403 Å) 主引用文献 Closed fumarase C active-site structures reveal SS Loop residue contribution in catalysis. Febs Lett., 594, 2020
7TOW	Antibody DH1058 Fab fragment bound to SARS-CoV-2 fusion peptide 分子名称: CALCIUM ION, DH1058 Fab Light chain, DH1058 Fab heavy chain, ... 著者 Gobeil, S, Acharya, P. 登録日 2022-01-24 公開日 2022-02-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
6NZA	Crystal structure of E. coli fumarase C K324A variant with closed SS Loop at 1.41 angstrom resolution 分子名称: CITRIC ACID, Fumarate hydratase class II 著者 Weaver, T.M, May, J.F, Bhattacharyya, B. 登録日 2019-02-13 公開日 2019-09-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.406 Å) 主引用文献 Closed fumarase C active-site structures reveal SS Loop residue contribution in catalysis. Febs Lett., 594, 2020
4Y12	Crystal structure of the S/T protein kinase PknG from Mycobacterium tuberculosis in complex with AGS 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PknG, ... 著者 Lisa, M.N, Alzari, P.M. 登録日 2015-02-06 公開日 2015-05-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis. Structure, 23, 2015
4Y0X	Crystal structure of the S/T protein kinase PknG from Mycobacterium tuberculosis in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase PknG, ... 著者 Lisa, M.N, Alzari, P.M. 登録日 2015-02-06 公開日 2015-05-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis. Structure, 23, 2015
8AS0	PD-1 extracellular domain in complex with Fab fragment from D12 antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ongaro, T, Scietti, L, Pluss, L, Peissert, F, Villa, A, Puca, E, De Luca, R, Neri, D, Forneris, F. 登録日 2022-08-17 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Selection of a PD-1 blocking antibody from a novel fully human phage display library. Protein Sci., 31, 2022
4DH8	Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, AMP-PNP and IP20 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
8DKF	Antibody DH1030.1 Fab fragment 分子名称: DH1030.1 Heavy chain, DH1030.1 Light chain 著者 Gobeil, S, Acharya, P. 登録日 2022-07-05 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 DH1030.1 glycan reactive Ab To Be Published
4DH3	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ATP and IP20 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
7XBJ	Txp40, an insecticidal toxin protein from Xenorhabdus nematophila 分子名称: 40kDa insecticidal toxin 著者 Kinkar, O, Kumar, A, Prashar, A, Hire, R.S, Makde, R.D. 登録日 2022-03-21 公開日 2023-03-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 The crystal structure of insecticidal protein Txp40 from Xenorhabdus nematophila reveals a two-domain unique binary toxin with homology to the toxin-antitoxin (TA) system. Insect Biochem.Mol.Biol., 164, 2023
4DH1	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with low Mg2+, ATP and IP20 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012

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