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7OE7
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Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-01
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OEB
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BU of 7oeb by Molmil
Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO]
分子名称: 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-02
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OJJ
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BU of 7ojj by Molmil
Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-16
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OE3
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BU of 7oe3 by Molmil
Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-01
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
4NLU
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BU of 4nlu by Molmil
Poliovirus Polymerase - G289A Loop Mutant
分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
著者Sholders, A.J, Peersen, O.B.
登録日2013-11-14
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLW
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BU of 4nlw by Molmil
Poliovirus Polymerase - G289A/C290I Loop Mutant
分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
著者Sholders, A.J, Peersen, O.B.
登録日2013-11-14
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLY
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BU of 4nly by Molmil
Poliovirus Polymerase - C290E Loop Mutant
分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
著者Sholders, A.J, Peersen, O.B.
登録日2013-11-14
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLR
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BU of 4nlr by Molmil
Poliovirus Polymerase - C290S Loop Mutant
分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
著者Sholders, A.J, Peersen, O.B.
登録日2013-11-14
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
7Z4O
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BU of 7z4o by Molmil
Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Pflug, A.
登録日2022-03-04
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z43
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BU of 7z43 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B
分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.123 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z42
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BU of 7z42 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B
分子名称: DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.418 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
5FJ6
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BU of 5fj6 by Molmil
Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T.
登録日2015-10-06
公開日2015-11-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5FJ7
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BU of 5fj7 by Molmil
Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex, with P1 included
分子名称: MAJOR INNER PROTEIN P1, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T.
登録日2015-10-06
公開日2015-11-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
2R7R
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BU of 2r7r by Molmil
Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC) complex
分子名称: RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7T
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BU of 2r7t by Molmil
Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGAACC) Complex
分子名称: RNA (5'-R(*UP*GP*UP*GP*AP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7S
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BU of 2r7s by Molmil
Crystal Structure of Rotavirus SA11 VP1 / RNA (UGUGCC) complex
分子名称: PHOSPHATE ION, RNA (5'-R(*UP*GP*UP*GP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7V
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BU of 2r7v by Molmil
Crystal Structure of Rotavirus SA11 VP1/RNA (GGCUUU) Complex
分子名称: RNA (5'-R(*G*GP*CP*UP*UP*U)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
8C4T
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BU of 8c4t by Molmil
Hantaan virus polymerase bound to its 5' viral RNA
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4U
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BU of 8c4u by Molmil
Hantaan virus polymerase in replication pre-initiation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*GP*CP*GP*GP*AP*GP*UP*AP*CP*UP*AP*CP*UP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4V
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BU of 8c4v by Molmil
Hantaan virus polymerase in replication elongation state
分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*CP*UP*AP*CP*UP*A)-3'), RNA (5'-R(P*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), ...
著者Durieux trouilleton, Q, Arragain, B, Malet, H.
登録日2023-01-04
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8CI5
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BU of 8ci5 by Molmil
Structure of the SNV L protein bound to 5' RNA
分子名称: RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L
著者Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-02-08
公開日2023-07-19
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional characterization of the Sin Nombre virus L protein.
Plos Pathog., 19, 2023
1HHT
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BU of 1hht by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template
分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2000-12-28
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI1
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BU of 1hi1 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-01
公開日2001-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1HI8
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BU of 1hi8 by Molmil
RNA dependent RNA polymerase from dsRNA bacteriophage phi6
分子名称: MAGNESIUM ION, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-03
公開日2001-03-27
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
7QTL
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BU of 7qtl by Molmil
Influenza A/H7N9 polymerase elongation complex
分子名称: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ...
著者Cusack, S, Kouba, T.
登録日2022-01-14
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023

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件を2024-06-12に公開中

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