7OE7
| Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-01 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OEB
| Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO] | 分子名称: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-02 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJJ
| Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OE3
| Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-01 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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4NLU
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4NLW
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4NLY
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4NLR
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7Z4O
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7Z43
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7Z42
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5FJ6
| Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. | 登録日 | 2015-10-06 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015
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5FJ7
| Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex, with P1 included | 分子名称: | MAJOR INNER PROTEIN P1, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. | 登録日 | 2015-10-06 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015
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2R7R
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC) complex | 分子名称: | RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | 著者 | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | 登録日 | 2007-09-09 | 公開日 | 2008-07-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7T
| Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGAACC) Complex | 分子名称: | RNA (5'-R(*UP*GP*UP*GP*AP*AP*CP*C)-3'), RNA-dependent RNA polymerase | 著者 | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | 登録日 | 2007-09-10 | 公開日 | 2008-07-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7S
| Crystal Structure of Rotavirus SA11 VP1 / RNA (UGUGCC) complex | 分子名称: | PHOSPHATE ION, RNA (5'-R(*UP*GP*UP*GP*CP*C)-3'), RNA-dependent RNA polymerase | 著者 | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | 登録日 | 2007-09-10 | 公開日 | 2008-07-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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2R7V
| Crystal Structure of Rotavirus SA11 VP1/RNA (GGCUUU) Complex | 分子名称: | RNA (5'-R(*G*GP*CP*UP*UP*U)-3'), RNA-dependent RNA polymerase | 著者 | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | 登録日 | 2007-09-10 | 公開日 | 2008-07-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16, 2008
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8C4T
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8C4U
| Hantaan virus polymerase in replication pre-initiation state | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*GP*CP*GP*GP*AP*GP*UP*AP*CP*UP*AP*CP*UP*A)-3'), ... | 著者 | Durieux trouilleton, Q, Arragain, B, Malet, H. | 登録日 | 2023-01-04 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
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8C4V
| Hantaan virus polymerase in replication elongation state | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*AP*CP*UP*AP*CP*UP*A)-3'), RNA (5'-R(P*AP*GP*GP*AP*GP*UP*AP*UP*CP*CP*AP*CP*CP*GP*CP*AP*AP*GP*A)-3'), ... | 著者 | Durieux trouilleton, Q, Arragain, B, Malet, H. | 登録日 | 2023-01-04 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication. Nat Commun, 14, 2023
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8CI5
| Structure of the SNV L protein bound to 5' RNA | 分子名称: | RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L | 著者 | Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2023-02-08 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional characterization of the Sin Nombre virus L protein. Plos Pathog., 19, 2023
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1HHT
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2000-12-28 | 公開日 | 2001-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI1
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2001-01-01 | 公開日 | 2001-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI8
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | 分子名称: | MAGNESIUM ION, P2 PROTEIN | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2001-01-03 | 公開日 | 2001-03-27 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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7QTL
| Influenza A/H7N9 polymerase elongation complex | 分子名称: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ... | 著者 | Cusack, S, Kouba, T. | 登録日 | 2022-01-14 | 公開日 | 2022-12-28 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
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