8AE8
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7E7F
| Human CYP11B1 mutant in complex with metyrapone | 分子名称: | CHOLIC ACID, Cytochrome P450 11B1, mitochondrial, ... | 著者 | Mukai, K, Sugimoto, H, Reiko, S, Matsuura, T, Hishiki, T, Kagawa, N. | 登録日 | 2021-02-26 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis. Curr Res Struct Biol, 3, 2021
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7E46
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7MK8
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7M8V
| Human CYP11B2 in complex with LCI699 | 分子名称: | 4-[(4R,5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile, Cytochrome P450 11B2, mitochondrial, ... | 著者 | Scott, E.E, Brixius-Anderko, S. | 登録日 | 2021-03-30 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Aldosterone Synthase Structure With Cushing Disease Drug LCI699 Highlights Avenues for Selective CYP11B Drug Design. Hypertension, 78, 2021
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7F3H
| Crystal structure of cytochrome P450DA heme domain | 分子名称: | Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SERINE, ... | 著者 | Wan, N.W. | 登録日 | 2021-06-16 | 公開日 | 2021-07-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Directed evolution of cytochrome P450DA hydroxylase activity for stereoselective biohydroxylation Catalysis Science And Technology, 12, 2022
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7JJ1
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2GR6
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1IO8
| Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: High resolution structural origin of its thermostability and functional properties | 分子名称: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2001-02-08 | 公開日 | 2001-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties J.Inorg.Biochem., 91, 2002
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1IO9
| THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | 分子名称: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2001-02-08 | 公開日 | 2001-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. J.Inorg.Biochem., 91, 2002
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2GQX
| Crystal structure of cytochrome p450cam mutant (f87w/y96f/l244a/v247l/c334a) with pentachlorobenzene | 分子名称: | 1,2,3,4,5-PENTACHLOROBENZENE, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Rao, Z, Wong, L.L, Xu, F, Bell, S.G. | 登録日 | 2006-04-22 | 公開日 | 2007-04-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam Protein Eng.Des.Sel., 20, 2007
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1IWI
| Putidaredoxin-Binding Stablilizes an Active Conformer of Cytochrome P450cam in its Reduced State; Crystal Structure of Cytochrome P450cam | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Nagano, S, Shimada, H, Tarumi, A, Hishiki, T, Kimata-Ariga, Y, Egawa, T, Park, S.-Y, Adachi, S, Shiro, Y, Ishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-05-15 | 公開日 | 2002-06-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Infrared spectroscopic and mutational studies on putidaredoxin-induced conformational changes in ferrous CO-P450cam Biochemistry, 42, 2003
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1IWJ
| Putidaredoxin-Binding Stablilizes an Active Conformer of Cytochrome P450cam in its Reduced State; Crystal Structure of Mutant(109K) Cytochrome P450cam | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Nagano, S, Shimada, H, Tarumi, A, Hishiki, T, Kimata-Ariga, Y, Egawa, T, Park, S.-Y, Adachi, S, Shiro, Y, Ishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-05-15 | 公開日 | 2002-06-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Infrared spectroscopic and mutational studies on putidaredoxin-induced conformational changes in ferrous CO-P450cam Biochemistry, 42, 2003
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1J51
| CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F/V247L/C334A) WITH 1,3,5-TRICHLOROBENZENE | 分子名称: | 1,3,5-TRICHLORO-BENZENE, CYTOCHROME P450CAM, POTASSIUM ION, ... | 著者 | Chen, X, Christopher, A, Jones, J, Guo, Q, Xu, F, Cao, R, Wong, L.L, Rao, Z. | 登録日 | 2002-01-05 | 公開日 | 2002-01-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the F87W/Y96F/V247L mutant of cytochrome P-450cam with 1,3,5-trichlorobenzene bound and further protein engineering for the oxidation of pentachlorobenzene and hexachlorobenzene J.BIOL.CHEM., 277, 2002
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2H7Q
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1IWK
| Putidaredoxin-Binding Stablilizes an Active Conformer of Cytochrome P450cam in its Reduced State; Crystal Structure of Mutant(112K) Cytochrome P450cam | 分子名称: | CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Nagano, S, Shimada, H, Tarumi, A, Hishiki, T, Kimata-Ariga, Y, Egawa, T, Park, S.-Y, Adachi, S, Shiro, Y, Ishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-05-15 | 公開日 | 2002-06-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Infrared spectroscopic and mutational studies on putidaredoxin-induced conformational changes in ferrous CO-P450cam Biochemistry, 42, 2003
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2H7R
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1IO7
| THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | 分子名称: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2001-02-08 | 公開日 | 2001-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. J.Inorg.Biochem., 91, 2002
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1IZO
| Cytochrome P450 BS beta Complexed with Fatty Acid | 分子名称: | Cytochrome P450 152A1, PALMITOLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lee, D.S, Yamada, A, Sugimoto, H, Matsunaga, I, Ogura, H, Ichihara, K, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-10-10 | 公開日 | 2003-03-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate Recognition and Molecular Mechanism of Fatty Acid Hydroxylation by Cytochrome P450 from Bacillus subtilis. CRYSTALLOGRAPHIC, SPECTROSCOPIC, AND MUTATIONAL STUDIES. J.Biol.Chem., 278, 2003
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2H7S
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2HPD
| CRYSTAL STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450'S | 分子名称: | CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ravichandran, K.G, Boddupalli, S.S, Hasemann, C.A, Peterson, J.A, Deisenhofer, J. | 登録日 | 1993-09-16 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's. Science, 261, 1993
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1JFB
| X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferric resting state at atomic resolution | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, nitric-oxide reductase cytochrome P450 55A1 | 著者 | Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2001-06-20 | 公開日 | 2001-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
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2HI4
| Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone | 分子名称: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1A2, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sansen, S, Yano, J.K, Reynald, R.L, Schoch, G.S, Stout, C.D, Johnson, E.F. | 登録日 | 2006-06-29 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2. J.Biol.Chem., 282, 2007
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1JIO
| P450eryF/6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 107A1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Cupp-Vickery, J.R, Garcia, C, Hofacre, A, McGee-Estrada, K. | 登録日 | 2001-07-02 | 公開日 | 2001-10-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. J.Mol.Biol., 311, 2001
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1K2O
| Cytochrome P450Cam with Bound BIS(2,2'-BIPYRIDINE)-(5-METHYL-2-2'-BIPYRIDINE)-C2-ADAMANTANE RUTHENIUM (II) | 分子名称: | CACODYLATE ION, Cytochrome P450CAM, DELTA-BIS(2,2'-BIPYRIDINE)-(5-METHYL-2-2'-BIPYRIDINE)-C2-ADAMANTANE RUTHENIUM (II), ... | 著者 | Dunn, A.R, Dmochowski, I.J, Bilwes, A.M, Gray, H.B, Crane, B.R. | 登録日 | 2001-09-28 | 公開日 | 2001-10-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Probing the open state of cytochrome P450cam with ruthenium-linker substrates. Proc.Natl.Acad.Sci.USA, 98, 2001
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