7B92
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7B91
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2GHP
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![BU of 2ghp by Molmil](/molmil-images/mine/2ghp) | Crystal structure of the N-terminal 3 RNA binding domains of the yeast splicing factor Prp24 | 分子名称: | U4/U6 snRNA-associated splicing factor PRP24 | 著者 | Bae, E, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2006-03-27 | 公開日 | 2006-04-25 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. J.Mol.Biol., 367, 2007
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4PKD
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![BU of 4pkd by Molmil](/molmil-images/mine/4pkd) | U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2 | 分子名称: | IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ... | 著者 | Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K. | 登録日 | 2014-05-14 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife, 4, 2015
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2VY4
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![BU of 2vy4 by Molmil](/molmil-images/mine/2vy4) | U11-48K CHHC ZN-FINGER DOMAIN | 分子名称: | U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION | 著者 | Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R. | 登録日 | 2008-07-17 | 公開日 | 2009-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009
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3PLU
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![BU of 3plu by Molmil](/molmil-images/mine/3plu) | Structure of Hub-1 protein in complex with Snu66 peptide (HINDI) | 分子名称: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | 著者 | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | 登録日 | 2010-11-15 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature, 474, 2011
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3PLV
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![BU of 3plv by Molmil](/molmil-images/mine/3plv) | Structure of Hub-1 protein in complex with Snu66 peptide (HINDII) | 分子名称: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | 著者 | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | 登録日 | 2010-11-15 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature, 474, 2011
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7OS2
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![BU of 7os2 by Molmil](/molmil-images/mine/7os2) | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-06-07 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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4MSX
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![BU of 4msx by Molmil](/molmil-images/mine/4msx) | Crystal structure of an essential yeast splicing factor | 分子名称: | ACETATE ION, Pre-mRNA-splicing factor SAD1, ZINC ION | 著者 | Hadjivassiliou, H, Guthrie, C, Rosenberg, O.S. | 登録日 | 2013-09-18 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. Rna, 20, 2014
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4M7A
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![BU of 4m7a by Molmil](/molmil-images/mine/4m7a) | Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA | 分子名称: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.781 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4M75
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![BU of 4m75 by Molmil](/molmil-images/mine/4m75) | Crystal structure of Lsm1-7 complex | 分子名称: | CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4M77
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![BU of 4m77 by Molmil](/molmil-images/mine/4m77) | Crystal structure of Lsm2-8 complex, space group I212121 | 分子名称: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.111 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4M7D
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![BU of 4m7d by Molmil](/molmil-images/mine/4m7d) | Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU | 分子名称: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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4M78
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![BU of 4m78 by Molmil](/molmil-images/mine/4m78) | Crystal structure of Lsm2-8 complex, space group P21 | 分子名称: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
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2OZB
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![BU of 2ozb by Molmil](/molmil-images/mine/2ozb) | Structure of a human Prp31-15.5K-U4 snRNA complex | 分子名称: | CALCIUM ION, RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, ... | 著者 | Liu, S, Luehrmann, R, Wahl, M.C. | 登録日 | 2007-02-26 | 公開日 | 2007-03-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science, 316, 2007
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7PX3
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![BU of 7px3 by Molmil](/molmil-images/mine/7px3) | Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | 登録日 | 2021-10-07 | 公開日 | 2022-01-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling. Nucleic Acids Res., 50, 2022
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8ENK
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1XWN
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![BU of 1xwn by Molmil](/molmil-images/mine/1xwn) | solution structure of cyclophilin like 1(PPIL1) and insights into its interaction with SKIP | 分子名称: | Peptidyl-prolyl cis-trans isomerase like 1 | 著者 | Xu, C, Xu, Y, Tang, Y, Wu, J, Shi, Y, Huang, Q, Zhang, Q. | 登録日 | 2004-11-01 | 公開日 | 2005-10-18 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of human peptidyl prolyl isomerase like protein 1 and insights into its interaction with SKIP J.Biol.Chem., 281, 2006
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7ZNK
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![BU of 7znk by Molmil](/molmil-images/mine/7znk) | Structure of an endogenous human TREX complex bound to mRNA | 分子名称: | RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ... | 著者 | Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. | 登録日 | 2022-04-21 | 公開日 | 2023-05-03 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
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2ALE
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![BU of 2ale by Molmil](/molmil-images/mine/2ale) | Crystal structure of yeast RNA splicing factor Snu13p | 分子名称: | MAGNESIUM ION, NHP2/L7aE family protein YEL026W | 著者 | Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T. | 登録日 | 2005-08-05 | 公開日 | 2006-10-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants. Biochem.Biophys.Res.Commun., 360, 2007
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5VSU
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![BU of 5vsu by Molmil](/molmil-images/mine/5vsu) | Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA | 分子名称: | Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... | 著者 | Montemayor, E.J. | 登録日 | 2017-05-12 | 公開日 | 2018-05-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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3SBG
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2OG4
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6RM9
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![BU of 6rm9 by Molmil](/molmil-images/mine/6rm9) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMB
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![BU of 6rmb by Molmil](/molmil-images/mine/6rmb) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | 著者 | Hamann, F, Neumann, P, Ficner, R. | 登録日 | 2019-05-06 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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