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7B92
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BU of 7b92 by Molmil
Structure of a minimal SF3B core in complex with sudemycin D6 (form II)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7B91
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Structure of a minimal SF3B core in complex with pladienolide D (form I)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-12-13
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
2GHP
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BU of 2ghp by Molmil
Crystal structure of the N-terminal 3 RNA binding domains of the yeast splicing factor Prp24
分子名称: U4/U6 snRNA-associated splicing factor PRP24
著者Bae, E, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-03-27
公開日2006-04-25
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and interactions of the first three RNA recognition motifs of splicing factor prp24.
J.Mol.Biol., 367, 2007
4PKD
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BU of 4pkd by Molmil
U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2
分子名称: IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ...
著者Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K.
登録日2014-05-14
公開日2014-12-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
2VY4
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BU of 2vy4 by Molmil
U11-48K CHHC ZN-FINGER DOMAIN
分子名称: U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
著者Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
登録日2008-07-17
公開日2009-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.
Structure, 17, 2009
3PLU
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BU of 3plu by Molmil
Structure of Hub-1 protein in complex with Snu66 peptide (HINDI)
分子名称: 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1
著者Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S.
登録日2010-11-15
公開日2011-06-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
3PLV
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BU of 3plv by Molmil
Structure of Hub-1 protein in complex with Snu66 peptide (HINDII)
分子名称: 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1
著者Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S.
登録日2010-11-15
公開日2011-06-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
7OS2
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BU of 7os2 by Molmil
Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78
分子名称: Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
登録日2021-06-07
公開日2022-02-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
4MSX
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BU of 4msx by Molmil
Crystal structure of an essential yeast splicing factor
分子名称: ACETATE ION, Pre-mRNA-splicing factor SAD1, ZINC ION
著者Hadjivassiliou, H, Guthrie, C, Rosenberg, O.S.
登録日2013-09-18
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing.
Rna, 20, 2014
4M7A
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BU of 4m7a by Molmil
Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA
分子名称: U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.781 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
4M75
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Crystal structure of Lsm1-7 complex
分子名称: CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-10-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
4M77
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BU of 4m77 by Molmil
Crystal structure of Lsm2-8 complex, space group I212121
分子名称: U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.111 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
4M7D
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BU of 4m7d by Molmil
Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU
分子名称: U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.595 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
4M78
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BU of 4m78 by Molmil
Crystal structure of Lsm2-8 complex, space group P21
分子名称: U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ...
著者Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y.
登録日2013-08-12
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Nature, 506, 2014
2OZB
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BU of 2ozb by Molmil
Structure of a human Prp31-15.5K-U4 snRNA complex
分子名称: CALCIUM ION, RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, ...
著者Liu, S, Luehrmann, R, Wahl, M.C.
登録日2007-02-26
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Science, 316, 2007
7PX3
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BU of 7px3 by Molmil
Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8
分子名称: Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C.
登録日2021-10-07
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
8ENK
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BU of 8enk by Molmil
Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Xie, Y, Ren, Y.
登録日2022-09-30
公開日2023-08-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
Cell Rep, 42, 2023
1XWN
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BU of 1xwn by Molmil
solution structure of cyclophilin like 1(PPIL1) and insights into its interaction with SKIP
分子名称: Peptidyl-prolyl cis-trans isomerase like 1
著者Xu, C, Xu, Y, Tang, Y, Wu, J, Shi, Y, Huang, Q, Zhang, Q.
登録日2004-11-01
公開日2005-10-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of human peptidyl prolyl isomerase like protein 1 and insights into its interaction with SKIP
J.Biol.Chem., 281, 2006
7ZNK
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BU of 7znk by Molmil
Structure of an endogenous human TREX complex bound to mRNA
分子名称: RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ...
著者Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C.
登録日2022-04-21
公開日2023-05-03
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
2ALE
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BU of 2ale by Molmil
Crystal structure of yeast RNA splicing factor Snu13p
分子名称: MAGNESIUM ION, NHP2/L7aE family protein YEL026W
著者Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T.
登録日2005-08-05
公開日2006-10-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.
Biochem.Biophys.Res.Commun., 360, 2007
5VSU
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BU of 5vsu by Molmil
Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA
分子名称: Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ...
著者Montemayor, E.J.
登録日2017-05-12
公開日2018-05-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Nat Commun, 9, 2018
3SBG
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BU of 3sbg by Molmil
Crystal structure of a Prp8 C-terminal fragment
分子名称: Pre-mRNA-splicing factor 8
著者Weber, G, Santos, K, Holton, N, Wahl, M.C.
登録日2011-06-04
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Mechanism for Aar2p function as a U5 snRNP assembly factor.
Genes Dev., 25, 2011
2OG4
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BU of 2og4 by Molmil
Structure of an expanded Jab1-MPN-like domain of splicing factor Prp8p from yeast
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Liu, S, Luehrmann, R, Wahl, M.C.
登録日2007-01-05
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.
Mol.Cell, 25, 2007
6RM9
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BU of 6rm9 by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Hamann, F, Neumann, P, Ficner, R.
登録日2019-05-06
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RMB
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BU of 6rmb by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ...
著者Hamann, F, Neumann, P, Ficner, R.
登録日2019-05-06
公開日2020-02-05
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020

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