PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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3UX3	Crystal Structure of Domain-Swapped Fam96a minor dimer 分子名称: ACETATE ION, MIP18 family protein FAM96A, ZINC ION 著者 Chen, K.-E, Kobe, B, Martin, J.L. 登録日 2011-12-03 公開日 2012-05-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallogr.,Sect.D, 68, 2012
3UMW	Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one 分子名称: (2Z)-2-(1H-indazol-3-ylmethylidene)-6-methoxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3(2H)-one, GLYCEROL, Proto-oncogene serine/threonine-protein kinase pim-1, ... 著者 Parker, L.J, Handa, N, Yokoyama, S. 登録日 2011-11-14 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound. J.Med.Chem., 55, 2012
6DPX	X-ray crystal structure of AmpC beta-lactamase with inhibitor 分子名称: (3-{[(3-chloro-2-hydroxyphenyl)sulfonyl]amino}phenyl)acetic acid, Beta-lactamase 著者 Singh, I. 登録日 2018-06-09 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ultra-large library docking for discovering new chemotypes. Nature, 566, 2019
3HBX	Crystal structure of GAD1 from Arabidopsis thaliana 分子名称: Glutamate decarboxylase 1 著者 Gut, H, Dominici, P, Pilati, S, Gruetter, M.G, Capitani, G. 登録日 2009-05-05 公開日 2009-07-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.672 Å) 主引用文献 A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase. J.Mol.Biol., 392, 2009
3UCS	Crystal structure of the complex between CBPA J-domain and CBPM 分子名称: Chaperone-modulator protein CbpM, Curved DNA-binding protein 著者 Shi, R, Sarraf, N.S, Cygler, M, Ekiel, I, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2011-10-27 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structure of the complex between CbpA J-domain and CbpM provides a link between chaperone and transcription regulation in bacterial heat shock response to be published
4UTN	Crystal structure of zebrafish Sirtuin 5 in complex with succinylated CPS1-peptide 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Pannek, M, Gertz, M, Steegborn, C. 登録日 2014-07-21 公開日 2014-08-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors. Angew.Chem.Int.Ed.Engl., 53, 2014
3H9Q	Crystal structure of E. coli MccB + SeMet MccA 分子名称: MccB protein, Microcin C7 ANALOG, SULFATE ION, ... 著者 Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. 登録日 2009-04-30 公開日 2009-06-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic. Embo J., 28, 2009
6Z5E	Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004093 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one, DIMETHYL SULFOXIDE, ... 著者 Chaikuad, A, Benderitter, P, Hoflack, J, Denis, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-05-26 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004093 To Be Published
1MEN	complex structure of human GAR Tfase and substrate beta-GAR 分子名称: GLYCINAMIDE RIBONUCLEOTIDE, Phosphoribosylglycinamide formyltransferase 著者 Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A. 登録日 2002-08-08 公開日 2002-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR Biochemistry, 41, 2002
4URR	Tailspike protein of Sf6 bacteriophage bound to Shigella flexneri O- antigen octasaccharide fragment 分子名称: 1,2-ETHANEDIOL, BIFUNCTIONAL TAIL PROTEIN, MANGANESE (II) ION, ... 著者 Gohlke, U, Heinemann, U, Seckler, R, Barbirz, S. 登録日 2014-07-01 公開日 2015-07-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein-Polysaccharide Interactions. J.Am.Chem.Soc., 138, 2016
3UIX	Crystal structure of Pim1 kinase in complex with small molecule inhibitor 分子名称: 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J. 登録日 2011-11-06 公開日 2012-04-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A novel pim-1 kinase inhibitor targeting residues that bind the substrate Peptide. J.Mol.Biol., 417, 2012
6ZDG	Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... 著者 Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. 登録日 2020-06-14 公開日 2020-07-29 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
6ZER	Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... 著者 Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. 登録日 2020-06-16 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
3HD2	Crystal structure of E. coli HPPK(Q50A) in complex with MgAMPCPP and pterin 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION, ... 著者 Blaszczyk, J, Li, Y, Yan, H, Ji, X. 登録日 2009-05-06 公開日 2010-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published
3UK3	Crystal structure of ZNF217 bound to DNA 分子名称: 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... 著者 Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. 登録日 2011-11-08 公開日 2012-12-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Rediscovering DNA recognition by classical Zinc Fingers. To be Published
4V45	E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE 分子名称: 2-deoxy-2-fluoro-beta-D-galactopyranose, Beta-Galactosidase, MAGNESIUM ION, ... 著者 Juers, D.H, McCarter, J.D, Withers, S.G, Matthews, B.W. 登録日 2001-09-13 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
1MEO	human glycinamide ribonucleotide Transformylase at pH 4.2 分子名称: PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase, SULFATE ION 著者 Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A. 登録日 2002-08-08 公開日 2002-12-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR Biochemistry, 41, 2002
3UKH	Crystal structure of udp-galactopyranose mutase from Aspergillus fumigatus in complex with UDPGALP (non-reduced) 分子名称: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Van Straaten, K.E, Sanders, D.A.R. 登録日 2011-11-09 公開日 2012-02-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus. J.Biol.Chem., 287, 2012
3HFN	Crystal Structure of an Hfq protein from Anabaena sp. 分子名称: Asl2047 protein 著者 Boggild, A, Overgaard, M, Valentin-Hansen, P, Brodersen, D.E. 登録日 2009-05-12 公開日 2009-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA-binding properties. Febs J., 276, 2009
4V5B	Structure of PDF binding helix in complex with the ribosome. 分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N. 登録日 2007-11-22 公開日 2014-07-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing. Nature, 452, 2008
3HGW	Apo Structure of Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase I87T mutant 分子名称: CALCIUM ION, Salicylate biosynthesis protein pchB 著者 Luo, Q, Lamb, A.L. 登録日 2009-05-14 公開日 2009-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme Biochemistry, 48, 2009
4V8N	The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site. 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V. 登録日 2013-02-13 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome Nat.Struct.Mol.Biol., 20, 2013
6ZCZ	Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... 著者 Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. 登録日 2020-06-12 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
4WAT	Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMIDAZOLE, PfRh5 著者 Chen, L. 登録日 2014-09-01 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes. Elife, 3, 2014
3UQP	Crystal structure of Bace1 with its inhibitor 分子名称: Beta-secretase 1, METHYL (2R)-1-[(6S,9S,12S,13S,17S,20S,23R)-9-(3-AMINO-3-OXOPROPYL)-12,23-DIBENZYL-13-HYDROXY-2,2,8,20,22-PENTAMETHYL-17-(2-METHYLPROPYL)-4,7,10,15,18,21,24-HEPTAOXO-6-(PROPAN-2-YL)-3-OXA-5,8,11,16,19,22-HEXAAZATETRACOSAN-24-YL]PYRROLIDINE-2-CARBOXYLATE, SULFATE ION 著者 Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. 登録日 2011-11-21 公開日 2012-11-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012

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