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7MX9

Crystal structure of the SARS-CoV-2 ORF8 accessory protein

Summary for 7MX9
Entry DOI10.2210/pdb7mx9/pdb
DescriptorORF8 protein (2 entities in total)
Functional Keywordssars-cov-2, covid19, orf8, immunoglobulin fold, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains1
Total formula weight12906.72
Authors
Bailey-Elkin, B.A.,Stetefeld, J. (deposition date: 2021-05-18, release date: 2023-01-25, Last modification date: 2023-10-25)
Primary citationHamdorf, M.,Imhof, T.,Theobald, S.J.,Simonis, A.,Di Cristanziano, V.,Gieselmann, L.,Dewald, F.,Lehmann, C.,Augustin, M.,Klein, F.,Alejandre Alcazar, M.A.,Rongisch, R.,Fabri, M.,Cursiefen, C.,Rybniker, J.,Bailey-Elkin, B.A.,Stetefeld, J.,Koch, M.,Bock, F.
The unique ORF8 protein of SARS-CoV-2 binds to human dendritic cells and induces a cytokine storm
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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