PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6WPF	Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and d4T 分子名称: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA Primer 21-mer, DNA template 27-mer, ... 著者 Bertoletti, N, Anderson, K.S. 登録日 2020-04-27 公開日 2020-11-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. Molecules, 25, 2020
7HAI	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-5525 分子名称: 2-(3-bromophenyl)-5-methyl-1,3,4-oxadiazole, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAO	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13777 分子名称: (3M)-3-(1H-pyrazol-1-yl)benzonitrile, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HA2	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14256 分子名称: 3-amino-4-methylbenzamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CLY	Structure of human DNA polymerase beta complexed with 8-ClG as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-03-02 公開日 2019-03-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.186 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 8-ClG as the template base in a 1-nucleotide gapped DNA To Be Published
7HA5	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-3550 分子名称: 1-[(4-bromophenyl)methyl]-1,4-diazepane, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
4P29	Crystal structure of the LpoA N-terminal domain from Haemophilus influenzae 分子名称: CHLORIDE ION, GLYCEROL, LpoA, ... 著者 Vijayalakshmi, J, Saper, M.A. 登録日 2014-03-02 公開日 2015-03-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.95006478 Å) 主引用文献 Structural analyses of theHaemophilus influenzaepeptidoglycan synthase activator LpoA suggest multiple conformations in solution. J.Biol.Chem., 292, 2017
7HAB	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12700 分子名称: (morpholin-4-yl)(phenyl)methanone, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAU	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13098 分子名称: Heat shock protein HSP 90-alpha, [2-(4-methylpiperazin-1-yl)phenyl]methanol 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HB8	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13480 分子名称: Heat shock protein HSP 90-alpha, N-[(1R,2R,4S)-bicyclo[2.2.1]hept-5-en-2-yl]-N-methylthiophene-2-carboxamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAK	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-6793 分子名称: 8-fluoro-2-methylquinolin-4-ol, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAG	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14186 分子名称: (3M)-3-(1H-imidazol-1-yl)benzonitrile, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBC	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13229 分子名称: 2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
4P2Y	Crystal structure of the human RAGE ectodomain (fragment VC1C2) in complex with mouse S100A6 分子名称: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ... 著者 Yatime, L, Andersen, G.R. 登録日 2014-03-05 公開日 2015-03-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. Structure, 2016
7HBO	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13368 分子名称: Heat shock protein HSP 90-alpha, N-[(1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl]-N'-butyl-N-methylurea 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HC0	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 4W-0801 分子名称: 3-(3-bromothiophen-2-yl)-1H-pyrazole, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
4P36	Crystal structure of DJ-1 With Zn(II) bound (crystal 2) 分子名称: 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Protein DJ-1, ZINC ION 著者 Tashiro, S, Wu, C.-X, Hoang, Q.Q, Caaveiro, J.M.M, Tsumoto, K. 登録日 2014-03-05 公開日 2014-04-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.182 Å) 主引用文献 Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1. Biochemistry, 53, 2014
1YTI	SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT 分子名称: PEPTIDE PRODUCT, SIV PROTEASE 著者 Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. 登録日 1996-08-01 公開日 1997-03-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Three-dimensional structures of HIV-1 and SIV protease product complexes. Biochemistry, 35, 1996
7HAV	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12879 分子名称: 3-amino-5-tert-butylthiophene-2-carboxamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HB2	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with FL0184 分子名称: 2-methoxy-7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAT	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12860 分子名称: (furan-2-yl)(thiomorpholin-4-yl)methanone, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HB9	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13464 分子名称: 2,5-dichlorothiophene-3-sulfonamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBG	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13237 分子名称: Heat shock protein HSP 90-alpha, N-methyl-1-{4-[(pyridin-2-yl)oxy]phenyl}methanamine 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBD	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12810 分子名称: Heat shock protein HSP 90-alpha, N-(3-chlorophenyl)-2-cyanoacetamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
8VLH	Crystal structure of Ash1L PHD-BAH domains 分子名称: Histone-lysine N-methyltransferase ASH1L, STRONTIUM ION, ZINC ION 著者 Vann, K.R, Tencer, A.H, Kutateladze, T.G. 登録日 2024-01-11 公開日 2025-03-19 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nat Commun, 16, 2025

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