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6X1I
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Two-Component D3 Assembly Constructed by Fusing Symmetric Oligomers to Coiled Coils
分子名称: Cob_adeno_trans domain-containing protein PH0671 fused to a coiled coil, SnoaL-like Protein fused to a coiled coil
著者Laniado, J, Yeates, T.O, Sawaya, M.R.
登録日2020-05-18
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.32 Å)
主引用文献Geometric Lessons and Design Strategies for Nanoscale Protein Cages.
Acs Nano, 15, 2021
6WG7
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BU of 6wg7 by Molmil
Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map
分子名称: DNA (35-MER), HTH-type transcriptional repressor NanR
著者Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
登録日2020-04-05
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
6WFQ
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BU of 6wfq by Molmil
NanR dimer-DNA hetero-complex
分子名称: DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3'), HTH-type transcriptional repressor NanR
著者Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
登録日2020-04-03
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
6RQT
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BU of 6rqt by Molmil
RNA Polymerase I-tWH-Rrn3-DNA
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-16
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6LIU
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BU of 6liu by Molmil
Crystal structure of apo Tyrosine decarboxylase
分子名称: Tyrosine/DOPA decarboxylase 2
著者Yu, J, Wang, H, Yao, M.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures clarify cofactor binding of plant tyrosine decarboxylase.
Biochem.Biophys.Res.Commun., 2019
6S2O
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BU of 6s2o by Molmil
Granulovirus occlusion bodies by serial electron diffraction
分子名称: Granulin
著者Buecker, R, Mehrabi, P, Schulz, E.C, Hogan-Lamarre, P.
登録日2019-06-21
公開日2020-04-29
最終更新日2020-11-18
実験手法ELECTRON CRYSTALLOGRAPHY (1.55 Å)
主引用文献Serial protein crystallography in an electron microscope.
Nat Commun, 11, 2020
6WPC
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BU of 6wpc by Molmil
Crystal structure of Bacillus thuringiensis Cry1A.2 tryptic core variant
分子名称: Cry1A.2
著者Rydel, T.J, Evdokimov, A.
登録日2020-04-27
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Bacillus thuringiensis chimeric proteins Cry1A.2 and Cry1B.2 to control soybean lepidopteran pests: New domain combinations enhance insecticidal spectrum of activity and novel receptor contributions.
Plos One, 16, 2021
6WVW
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BU of 6wvw by Molmil
Crystal structure of the R59P-SNAP25 containing SNARE complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Synaptosomal-associated protein 25, ...
著者Zhou, Q, White, K.I, Brunger, A.T.
登録日2020-05-07
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.
Neuron, 109, 2021
6RUI
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BU of 6rui by Molmil
RNA Polymerase I Pre-initiation complex DNA opening intermediate 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-28
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6L7S
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BU of 6l7s by Molmil
Crystal structure of FKRP in complex with Mg ion, Zinc peak data
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fukutin-related protein, MAGNESIUM ION, ...
著者Kuwabara, N.
登録日2019-11-03
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.
Nat Commun, 11, 2020
6L93
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BU of 6l93 by Molmil
X-ray structure of the ligand-free human TRPV1 ankyrin repeat domain
分子名称: Transient receptor potential cation channel subfamily V member 1
著者Tanaka, M, Hayakawa, K, Unno, M.
登録日2019-11-08
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions.
Acta Crystallogr.,Sect.F, 76, 2020
6LCP
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BU of 6lcp by Molmil
Cryo-EM structure of Dnf1 from Chaetomium thermophilum in the E2P state
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者He, Y, Xu, J, Wu, X, Li, L.
登録日2019-11-19
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structures of a P4-ATPase lipid flippase in lipid bilayers.
Protein Cell, 11, 2020
6LDN
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BU of 6ldn by Molmil
Crystal structure of T.onnurineus Csm5
分子名称: Csm5
著者Park, K.H, Woo, E.J.
登録日2019-11-22
公開日2020-11-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Csm5 subunit of the Type III-A Csm complex at 2.6 Angstroms resolution
To Be Published
6RVR
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BU of 6rvr by Molmil
Atomic structure of the Epstein-Barr portal, structure I
分子名称: Portal protein
著者Machon, C, Fabrega-Ferrer, M, Zhou, D, Cuervo, A, Carrascosa, J.L, Stuart, D.I, Coll, M.
登録日2019-05-31
公開日2019-09-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Atomic structure of the Epstein-Barr virus portal.
Nat Commun, 10, 2019
6WZW
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BU of 6wzw by Molmil
Ash1L SET domain in complex with AS-85
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histone-lysine N-methyltransferase ASH1L, N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl)sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide, ...
著者Li, H, Deng, J, Cierpicki, T, Grembecka, J.
登録日2020-05-14
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
Nat Commun, 12, 2021
6X0P
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BU of 6x0p by Molmil
Ash1L SET domain Q2265A mutant in complex with AS-5
分子名称: 3-[6-(aminomethyl)-1-(2-hydroxyethyl)-1H-indol-3-yl]benzene-1-carbothioamide, Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ...
著者Rogawski, D.S, Li, H, Borkin, D, Cierpicki, T, Grembecka, J.
登録日2020-05-17
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
Nat Commun, 12, 2021
6S2N
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BU of 6s2n by Molmil
Hen egg-white lysozyme by serial electron diffraction
分子名称: Lysozyme C
著者Buecker, R, Mehrabi, P, Schulz, E.C, Hogan-Lamarre, P.
登録日2019-06-21
公開日2020-04-29
最終更新日2020-11-18
実験手法ELECTRON CRYSTALLOGRAPHY (1.8 Å)
主引用文献Serial protein crystallography in an electron microscope.
Nat Commun, 11, 2020
6WI3
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BU of 6wi3 by Molmil
Histone deacetylases complex with peptide macrocycles
分子名称: (SHA)W(DTH)DN(DSN)(DME)(DAS)K peptide macrocycle, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Histone deacetylase 2, ...
著者Bera, A.K, Hosseinzadeh, P, Watson, P, Baker, D.
登録日2020-04-08
公開日2021-04-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Nat Commun, 12, 2021
6WJU
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BU of 6wju by Molmil
Fab Fragment of Anti-human LAG3 antibody (4A10)
分子名称: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain
著者Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
登録日2020-04-14
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Fab Fragment of Anti-human LAG3 antibody
To Be Published
6L7R
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BU of 6l7r by Molmil
Crystal structure of Chaetomium GCP3 N-terminus and Mozart1
分子名称: Mozart1, Putative spindle pole body component alp6 protein
著者Huang, T.L, Wang, H.J, Hsia, K.C.
登録日2019-11-02
公開日2020-07-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8481313 Å)
主引用文献Promiscuous Binding of Microprotein Mozart1 to gamma-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation.
Cell Rep, 31, 2020
6WSJ
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BU of 6wsj by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with cyclopeptide des4.3.1
分子名称: 1,2-ETHANEDIOL, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2020-05-01
公開日2021-04-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Nat Commun, 12, 2021
6WKL
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BU of 6wkl by Molmil
Fab Fragment of Anti-human LAG3 antibody (BAP050)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain
著者Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
登録日2020-04-16
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKM
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BU of 6wkm by Molmil
Fab Fragment of Anti-human LAG3 antibody (22D2)
分子名称: 22D2 Fab Heavy Chain, 22D2 Fab Light Chain
著者Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
登録日2020-04-16
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 2023
6L8F
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BU of 6l8f by Molmil
Crystal structure of heterotetrameric complex of YoeB-YefM toxin-antitoxin from Staphylococcus aureus.
分子名称: Antitoxin, YoeB
著者Yue, J, Xue, L.
登録日2019-11-06
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system.
Nucleic Acids Res., 48, 2020
6WRW
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BU of 6wrw by Molmil
Crystal structure of computationally designed protein 2DS25.5 in complex with the human Transferrin receptor ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Computationally designed protein 2DS25.5, ...
著者Abraham, J, Coscia, A, Olal, D, Sahtoe, D.D, Baker, D, Clark, L.
登録日2020-04-30
公開日2021-04-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Transferrin receptor targeting by de novo sheet extension.
Proc.Natl.Acad.Sci.USA, 118, 2021

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