7KHW
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7L0Y
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3F15
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5F14
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3EZV
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![BU of 3ezv by Molmil](/molmil-images/mine/3ezv) | CDK-2 with indazole inhibitor 9 bound at its active site | 分子名称: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | 著者 | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | 登録日 | 2008-10-23 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
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4HKQ
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![BU of 4hkq by Molmil](/molmil-images/mine/4hkq) | XMRV reverse transcriptase in complex with RNA/DNA hybrid | 分子名称: | DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*A*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), RNA (5'-R(*AP*AP*CP*AP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*CP*AP*U)-3'), Reverse transcriptase/ribonuclease H p80 | 著者 | Nowak, E, Potrzebowski, W, Konarev, P.V, Rausch, J.W, Bona, M.K, Svergun, D.I, Bujnicki, J.M, Le Grice, S.F.J, Nowotny, M. | 登録日 | 2012-10-15 | 公開日 | 2013-02-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid Nucleic Acids Res., 41, 2013
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5F3G
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![BU of 5f3g by Molmil](/molmil-images/mine/5f3g) | Crystal structure of human KDM4A in complex with compound 53a | 分子名称: | 8-[4-[2-[4-[(4-chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Le Bihan, Y.-V, Westwood, I.M, van Montfort, R.L.M. | 登録日 | 2015-12-02 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
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4HL4
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![BU of 4hl4 by Molmil](/molmil-images/mine/4hl4) | Crystal structure of the human TBC1D20 RabGAP domain | 分子名称: | ACETATE ION, BERYLLIUM TRIFLUORIDE ION, TBC1 domain family member 20 | 著者 | Gazdag, E.M, Gavriljuk, K, Itzen, A, Koetting, C, Gerwert, K, Goody, R.S. | 登録日 | 2012-10-16 | 公開日 | 2013-01-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail. Proc.Natl.Acad.Sci.USA, 109, 2012
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7POE
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![BU of 7poe by Molmil](/molmil-images/mine/7poe) | Phosphoglycolate Phosphatase with Inhibitor CP1 | 分子名称: | 2-[[4-[4-[(2-carboxyphenyl)carbamoyl]phenoxy]phenyl]carbonylamino]benzoic acid, GLYCEROL, Glycerol-3-phosphate phosphatase, ... | 著者 | Schloetzer, J, Fratz, S, Schindelin, H. | 登録日 | 2021-09-08 | 公開日 | 2022-12-21 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Glycolytic flux control by drugging phosphoglycolate phosphatase. Nat Commun, 13, 2022
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5CCM
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![BU of 5ccm by Molmil](/molmil-images/mine/5ccm) | Crystal structure of SMYD3 with SAM and EPZ030456 | 分子名称: | 6-chloranyl-2-oxidanylidene-N-[(1S,5R)-8-[4-[(phenylmethyl)amino]piperidin-1-yl]sulfonyl-8-azabicyclo[3.2.1]octan-3-yl]-1,3-dihydroindole-5-carboxamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | 著者 | Boriack-Sjodin, P.A. | 登録日 | 2015-07-02 | 公開日 | 2015-09-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor. Acs Med.Chem.Lett., 7, 2016
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4HS1
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1O0T
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![BU of 1o0t by Molmil](/molmil-images/mine/1o0t) | CRYSTAL STRUCTURE OF A COLD ADAPTED ALKALINE PROTEASE FROM PSEUDOMONAS TAC II 18, CO-CRYSTALLIZED WITH 5 mM EDTA (5 DAYS) | 分子名称: | CALCIUM ION, SULFATE ION, serralysin | 著者 | Ravaud, S, Gouet, P, Haser, R, Aghajari, N. | 登録日 | 2003-02-24 | 公開日 | 2003-07-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Probing the role of divalent metal ions in a bacterial psychrophilic metalloprotease: binding studies of an enzyme in the crystalline state by x-ray crystallography. J.Bacteriol., 185, 2003
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7KRD
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![BU of 7krd by Molmil](/molmil-images/mine/7krd) | Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 4-(3-chloro-5-cyanophenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenyl sulfurofluoridate (JLJ702) | 分子名称: | 4-(3-chloro-5-cyanophenoxy)-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... | 著者 | Bertoletti, N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. | 登録日 | 2020-11-19 | 公開日 | 2021-01-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. Acs Med.Chem.Lett., 12, 2021
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2DVN
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3F32
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![BU of 3f32 by Molmil](/molmil-images/mine/3f32) | Horse spleen apoferritin | 分子名称: | CADMIUM ION, Ferritin light chain, SULFATE ION | 著者 | Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J. | 登録日 | 2008-10-30 | 公開日 | 2009-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A unitary anesthetic binding site at high resolution. J.Biol.Chem., 284, 2009
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2DW1
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![BU of 2dw1 by Molmil](/molmil-images/mine/2dw1) | Crystal structure of VAP2 from Crotalus atrox venom (Form 2-2 crystal) | 分子名称: | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, CALCIUM ION, Catrocollastatin, ... | 著者 | Takeda, S, Igarashi, T, Araki, S. | 登録日 | 2006-08-02 | 公開日 | 2007-07-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins Febs Lett., 581, 2007
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3F3F
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![BU of 3f3f by Molmil](/molmil-images/mine/3f3f) | Crystal structure of the nucleoporin pair Nup85-Seh1, space group P21 | 分子名称: | Nucleoporin NUP85, Nucleoporin SEH1 | 著者 | Debler, E.W, Hseo, H, Ma, Y, Blobel, G, Hoelz, A. | 登録日 | 2008-10-30 | 公開日 | 2009-04-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A fence-like coat for the nuclear pore membrane. Mol.Cell, 32, 2008
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5F75
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![BU of 5f75 by Molmil](/molmil-images/mine/5f75) | Thiocyanate dehydrogenase from Thioalkalivibrio paradoxus | 分子名称: | COPPER (II) ION, Thiocyanate dehydrogenase | 著者 | Tsallagov, S.I, Polyakov, K.M, Tikhonova, T.V, Trofimov, A.A, Shabalin, I.G, Popov, A.N, Popov, V.O. | 登録日 | 2015-12-07 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thiocyanate dehydrogenase from Thioalkalivibrio paradoxus To Be Published
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3A4P
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![BU of 3a4p by Molmil](/molmil-images/mine/3a4p) | human c-MET kinase domain complexed with 6-benzyloxyquinoline inhibitor | 分子名称: | (2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide, CHLORIDE ION, Hepatocyte growth factor receptor, ... | 著者 | Fukami, T.A, Kadono, S, Yamamuro, M, Matsuura, T. | 登録日 | 2009-07-13 | 公開日 | 2010-02-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Discovery of 6-benzyloxyquinolines as c-Met selective kinase inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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1O1A
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![BU of 1o1a by Molmil](/molmil-images/mine/1o1a) | MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE | 分子名称: | SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ... | 著者 | Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. | 登録日 | 2002-11-18 | 公開日 | 2002-12-04 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (70 Å) | 主引用文献 | Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.Struct.Biol., 138, 2002
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8TD4
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![BU of 8td4 by Molmil](/molmil-images/mine/8td4) | Structure of PYCR1 complexed with NADH and 1,3-Dithiolane-2-carboxylic acid | 分子名称: | 1,3-dithiolane-2-carboxylic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Pyrroline-5-carboxylate reductase 1, ... | 著者 | Tanner, J.J, Meeks, K.R. | 登録日 | 2023-07-02 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1) Protein Sci., 33, 2024
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3AF8
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![BU of 3af8 by Molmil](/molmil-images/mine/3af8) | Crystal Structure of Pd(ally)/apo-C126AFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... | 著者 | Abe, S, Hikage, T, Watanabe, Y, Kitagawa, S, Ueno, T. | 登録日 | 2010-02-24 | 公開日 | 2010-08-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Mechanism of Accumulation and Incorporation of Organometallic Pd Complexes into the Protein Nanocage of apo-Ferritin. Inorg.Chem., 49, 2010
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3A5L
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![BU of 3a5l by Molmil](/molmil-images/mine/3a5l) | Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Gelsolin, ... | 著者 | Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T. | 登録日 | 2009-08-09 | 公開日 | 2010-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release Cell(Cambridge,Mass.), 143, 2010
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3F1I
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![BU of 3f1i by Molmil](/molmil-images/mine/3f1i) | Human ESCRT-0 Core Complex | 分子名称: | Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1 | 著者 | Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H. | 登録日 | 2008-10-28 | 公開日 | 2009-03-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Hybrid Structural Model of the Complete Human ESCRT-0 Complex. Structure, 17, 2009
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4HOA
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![BU of 4hoa by Molmil](/molmil-images/mine/4hoa) | Crystal structure of the complex of type 1 ribosome inactivating protein from Momordica Balsamina with B-D-galactopyranosyl-(1-4)-D-glucose at 2.0 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Yamini, S, Pandey, N, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2012-10-22 | 公開日 | 2012-11-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the complex of type 1 ribosome inactivating protein from Momordica Balsamina with B-D-galactopyranosyl-(1-4)-D-glucose at 2.0 A resolution To be Published
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