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1HFI
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SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
分子名称: FACTOR H, 15TH C-MODULE PAIR
著者Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
登録日1993-02-23
公開日1993-07-15
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
4RUX
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BU of 4rux by Molmil
Crystal structure of human Carbonic Anhydrase II in complex with 4-(allyloxy)benzenesulfonamide
分子名称: 4-(allyloxy)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
著者Pinard, M.A, Mckenna, R.
登録日2014-11-23
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.
Bioorg.Med.Chem., 23, 2015
1N32
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Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
登録日2002-10-25
公開日2002-11-29
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002
4ZOT
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BU of 4zot by Molmil
Crystal structure of BbKI, a disulfide-free plasma kallikrein inhibitor at 1.4 A resolution
分子名称: Kunitz-type serine protease inhibitor BbKI
著者Shabalin, I.G, Zhou, D, Wlodawer, A, Oliva, M.L.V.
登録日2015-05-06
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of BbKI, a disulfide-free plasma kallikrein inhibitor.
Acta Crystallogr.,Sect.F, 71, 2015
1HXW
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BU of 1hxw by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538
分子名称: HIV-1 PROTEASE, RITONAVIR
著者Park, C.H, Nienaber, V, Kong, X.P.
登録日1997-01-24
公開日1998-02-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
Proc.Natl.Acad.Sci.USA, 92, 1995
5E5F
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BU of 5e5f by Molmil
X-ray structure of the complex between RNase A and compound 4-PF6 ([(PPh3)Au(mi-pbi)Pt(Me)(DMSO)][PF6]), the heterobimetallic derivative obtained in the reaction between the organometallic compound [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3) and the gold(I) compound [Au(Ph3P)][PF6]
分子名称: ACETATE ION, GOLD ION, Ribonuclease pancreatic, ...
著者Merlino, A.
登録日2015-10-08
公開日2015-12-09
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
5AO9
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The structure of a novel thermophilic esterase from the Planctomycetes species, Thermogutta terrifontis, Est2-native
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Sayer, C, Szabo, Z, Isupov, M.N, Ingham, C, Littlechild, J.A.
登録日2015-09-10
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The Structure of a Novel Thermophilic Esterase from the Planctomycetes Species, Thermogutta Terrifontis Reveals an Open Active Site due to a Minimal 'CAP' Domain.
Front.Microbiol., 6, 2015
5HPF
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BU of 5hpf by Molmil
Crystal Structure of the Double Mutant of PobR Transcription Factor Inducer Binding Domain from Acinetobacter
分子名称: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
著者Kim, Y, Tesar, C, Jedrejczak, R, Jha, R, Strauss, C.E.M, Joachimiak, A.
登録日2016-01-20
公開日2016-09-07
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.309 Å)
主引用文献A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor.
Nucleic Acids Res., 44, 2016
5AGY
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BU of 5agy by Molmil
CRYSTAL STRUCTURE OF A TAU CLASS GST MUTANT FROM GLYCINE
分子名称: 4-NITROPHENYL METHANETHIOL, GLUTATHIONE S-TRANSFERASE, PHOSPHATE ION, ...
著者Axarli, I, Muleta, A.W, Vlachakis, D, Kossida, S, Kotzia, G, Dhavala, P, Papageorgiou, A.C, Labrou, N.E.
登録日2015-02-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Directed Evolution of Tau Class Glutathione Transferases Reveals a Site that Regulates Catalytic Efficiency and Masks Cooperativity.
Biochem.J., 473, 2016
5ACC
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BU of 5acc by Molmil
A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models
分子名称: (E)-3-(3,5-DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2- METHYLPROPYL)-3-METHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC ACID, ESTROGEN RECEPTOR
著者Norman, R.A, Weir, H.M, Bradbury, R.H, Lawson, M, Rabow, A.A, Buttar, D, Callis, R.J, Curwen, J.O, de Almeida, C, Ballard, P, Hulse, M, Donald, C.S, Feron, L.J.L, Gingell, H, Karoutchi, G, MacFaul, P, Moss, T, Pearson, S.E, Tonge, M, Davies, G, Walker, G.E, Wilson, Z, Rowlinson, R, Powell, S, Hemsley, P, Linney, E, Campbell, H, Ghazoui, Z, Sadler, C, Richmond, G, Pazolli, E, Mazzola, A.M, DCruz, C, De Savi, C.
登録日2015-08-15
公開日2015-12-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
J.Med.Chem., 58, 2015
6EGO
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BU of 6ego by Molmil
Crystal Structure of a de Novo Three-stranded Coiled Coil Peptide Containing an Ala Residue in the Second Coordination Sphere of the Hg(II)S3 Binding Site
分子名称: Hg(II)(GRAND CoilSerL12AL16C)3-, MERCURY (II) ION, ZINC ION
著者Ruckthong, L, Stuckey, J.A, Pecoraro, V.L.
登録日2018-08-20
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation.
Chemistry, 25, 2019
5AOB
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BU of 5aob by Molmil
The structure of a novel thermophilic esterase from the Planctomycetes species, Thermogutta terrifontis, Est2-butyrate bound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sayer, C, Szabo, Z, Isupov, M.N, Ingham, C, Littlechild, J.A.
登録日2015-09-10
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The Structure of a Novel Thermophilic Esterase from the Planctomycetes Species, Thermogutta Terrifontis Reveals an Open Active Site due to a Minimal 'CAP' Domain.
Front.Microbiol., 6, 2015
5AOC
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BU of 5aoc by Molmil
The structure of a novel thermophilic esterase from the Planctomycetes species, Thermogutta terrifontis, Est2-valerate bound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sayer, C, Szabo, Z, Isupov, M.N, Ingham, C, Littlechild, J.A.
登録日2015-09-10
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The Structure of a Novel Thermophilic Esterase from the Planctomycetes Species, Thermogutta Terrifontis Reveals an Open Active Site due to a Minimal 'CAP' Domain.
Front.Microbiol., 6, 2015
5AOA
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BU of 5aoa by Molmil
The structure of a novel thermophilic esterase from the Planctomycetes species, Thermogutta terrifontis, Est2-Propionate bound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sayer, C, Szabo, Z, Isupov, M.N, Ingham, C, Littlechild, J.A.
登録日2015-09-10
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The Structure of a Novel Thermophilic Esterase from the Planctomycetes Species, Thermogutta Terrifontis Reveals an Open Active Site due to a Minimal 'CAP' Domain.
Front.Microbiol., 6, 2015
7BNT
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BU of 7bnt by Molmil
Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikD with a predicted ancestral HMA domain of Pik-1 from Oryza spp.
分子名称: 1,2-ETHANEDIOL, AVR-Pik protein, Predicted ancestral HMA domain of Pik-1 from Oryza spp.
著者Bialas, A, Langner, T, Harant, A, Contreras, M.P, Stevenson, C.E.M, Lawson, D.M, Sklenar, J, Kellner, R, Moscou, M.J, Terauchi, R, Banfield, M.J, Kamoun, S.
登録日2021-01-22
公開日2021-02-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Two NLR immune receptors acquired high-affinity binding to a fungal effector through convergent evolution of their integrated domain.
Elife, 10, 2021
7BW2
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BU of 7bw2 by Molmil
Crystal Structure of Cyanobacterial PSI Monomer from T.elongatus at 6.5 A Resolution
分子名称: Photosystem I 4.8K protein, Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I P700 chlorophyll a apoprotein A2, ...
著者Kurisu, G, Coruh, O, Tanaka, H, Eithar, E.M, Mian, Y.
登録日2020-04-13
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster.
Commun Biol, 4, 2021
7JP2
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BU of 7jp2 by Molmil
Crystal structure of TP0037 from Treponema pallidum, a D-lactate dehydrogenase
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, D-lactate dehydrogenase
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2020-08-07
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum.
Mbio, 11, 2020
4YE1
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BU of 4ye1 by Molmil
A cytochrome c plus calixarene structure - alternative ligand binding mode
分子名称: 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, Cytochrome c iso-1, GLYCEROL, ...
著者Mallon, M.M, McGovern, R.E, McCarty, A.A, Crowley, P.B.
登録日2015-02-23
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献A cytochrome c-calixarene structure
To Be Published
5E5E
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BU of 5e5e by Molmil
X-ray structure of the adduct formed in the reaction between RNase A and a neutral organometallic derivative [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3)
分子名称: DIMETHYL SULFOXIDE, PLATINUM (II) ION, Ribonuclease pancreatic
著者Merlino, A.
登録日2015-10-08
公開日2015-12-09
最終更新日2016-01-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
4XLR
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BU of 4xlr by Molmil
Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA
分子名称: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
1HLL
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BU of 1hll by Molmil
NMR STRUCTURE OF T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA-2A ADRENERGIC RECEPTOR
分子名称: ALPHA-2A ADRENERGIC RECEPTOR
著者Chung, D.A, Zuiderweg, E.R.P, Neubig, R.R.
登録日2000-12-01
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
1HOF
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BU of 1hof by Molmil
NMR STRUCTURE OF T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA-2A ADRENERGIC RECEPTOR
分子名称: ALPHA-2A ADRENERGIC RECEPTOR
著者Chung, D.A, Zuiderweg, E.R, Neubig, R.R.
登録日2000-12-10
公開日2002-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
6H4C
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, NICKEL (II) ION, ...
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
6H48
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: Orf20
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
6H49
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: Orf20, SULFATE ION
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019

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