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5Y53
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Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site
分子名称: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-08-07
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5GM6
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BU of 5gm6 by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y.
登録日2016-07-12
公開日2016-09-21
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Science, 353, 2016
5GMK
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BU of 5gmk by Molmil
Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution
分子名称: 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y.
登録日2016-07-14
公開日2016-08-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution
Science, 353, 2016
4BG6
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BU of 4bg6 by Molmil
14-3-3 interaction with Rnd3 prenyl-phosphorylation motif
分子名称: 14-3-3 PROTEIN ZETA/DELTA, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FARNESYL, ...
著者Riou, P, Kjaer, S, Purkiss, A, O'Reilly, N, McDonald, N.Q.
登録日2013-03-23
公開日2013-05-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins.
Cell(Cambridge,Mass.), 153, 2013
4ACG
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BU of 4acg by Molmil
GSK3b in complex with inhibitor
分子名称: 2-AMINO-5-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-[4-(PYRROLIDIN-1-YLMETHYL)PYRIDIN-3-YL]PYRIDINE-3-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Xue, Y, Ormo, M.
登録日2011-12-15
公開日2012-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
2Q8K
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BU of 2q8k by Molmil
The crystal structure of Ebp1
分子名称: GLYCEROL, Proliferation-associated protein 2G4, SULFATE ION
著者Kowalinski, E, Bange, G, Wild, K, Sinning, I.
登録日2007-06-11
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions.
Febs Lett., 581, 2007
4ACC
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BU of 4acc by Molmil
GSK3b in complex with inhibitor
分子名称: 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, DIMETHYL SULFOXIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Xue, Y, Ormo, M.
登録日2011-12-14
公開日2012-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
3J2I
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BU of 3j2i by Molmil
Structure of late pre-60S ribosomal subunits with nuclear export factor Arx1 bound at the peptide exit tunnel
分子名称: Eukaryotic translation initiation factor 6, Proliferation-associated protein 2G4
著者Bradatsch, B, Leidig, C, Granneman, S, Gnaedig, M, Tollervey, D, Boettcher, B, Beckmann, R, Hurt, E.
登録日2012-10-04
公開日2012-11-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (11.9 Å)
主引用文献Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel.
Nat.Struct.Mol.Biol., 19, 2012
3OGM
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BU of 3ogm by Molmil
Structure of COI1-ASK1 in complex with coronatine and the JAZ1 degron
分子名称: (1S,2S)-2-ethyl-1-({[(3aS,4S,6R,7aS)-6-ethyl-1-oxooctahydro-1H-inden-4-yl]carbonyl}amino)cyclopropanecarboxylic acid, Coronatine-insensitive protein 1, JAZ1 degron peptide, ...
著者Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N.
登録日2010-08-17
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Nature, 468, 2010
4YDH
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BU of 4ydh by Molmil
The structure of human FMNL1 N-terminal domains bound to Cdc42
分子名称: Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ...
著者Kuhn, S, Anand, K, Geyer, M.
登録日2015-02-22
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.
Nat Commun, 6, 2015
7WTS
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BU of 7wts by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State UTP14
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
7D9V
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BU of 7d9v by Molmil
CRTC1 pSer245 peptide in complex with 14-3-3 zeta
分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer245 peptide, GLYCEROL
著者Chen, H, Zhang, H, Xiang, S.
登録日2020-10-14
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Insights into the Interaction Between CRTCs and 14-3-3.
J.Mol.Biol., 433, 2021
7D8P
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BU of 7d8p by Molmil
CRTC1 pSer151 peptide in complex with 14-3-3 zeta
分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer151 peptide, GLYCEROL
著者Chen, H, Zhang, H, Xiang, S.
登録日2020-10-08
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the Interaction Between CRTCs and 14-3-3.
J.Mol.Biol., 433, 2021
7D8H
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BU of 7d8h by Molmil
CRTC1 pSer64 peptide in complex with 14-3-3 zeta
分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer64 peptide
著者Chen, H, Zhang, H, Xiang, S.
登録日2020-10-08
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Insights into the Interaction Between CRTCs and 14-3-3.
J.Mol.Biol., 433, 2021
2C1N
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BU of 2c1n by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-16
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
2C1J
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BU of 2c1j by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-15
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
4ACD
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BU of 4acd by Molmil
GSK3b in complex with inhibitor
分子名称: 3-AMINO-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Xue, Y, Ormo, M.
登録日2011-12-15
公開日2012-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
4ACH
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BU of 4ach by Molmil
GSK3b in complex with inhibitor
分子名称: 3-AMINO-N-(3-METHOXYPROPYL)-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}PYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
著者Xue, Y, Ormo, M.
登録日2011-12-15
公開日2012-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
7EXE
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BU of 7exe by Molmil
Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide
分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22
著者Yan, L, Okatsu, K, Fukai, S.
登録日2021-05-27
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice
Cell Rep, 2021
3OGL
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BU of 3ogl by Molmil
Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron
分子名称: Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, N-({(1R,2S)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetyl)-L-isoleucine, ...
著者Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N.
登録日2010-08-17
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Nature, 468, 2010
3OGK
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BU of 3ogk by Molmil
Structure of COI1-ASK1 in complex with coronatine and an incomplete JAZ1 degron
分子名称: (1S,2S)-2-ethyl-1-({[(3aS,4S,6R,7aS)-6-ethyl-1-oxooctahydro-1H-inden-4-yl]carbonyl}amino)cyclopropanecarboxylic acid, Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, ...
著者Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N.
登録日2010-08-16
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
Nature, 468, 2010
2UYZ
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BU of 2uyz by Molmil
Non-covalent complex between Ubc9 and SUMO1
分子名称: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9
著者Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K.
登録日2007-04-21
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.
EMBO J., 26, 2007
2V6C
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BU of 2v6c by Molmil
Crystal structure of ErbB3 binding protein 1 (Ebp1)
分子名称: PROLIFERATION-ASSOCIATED PROTEIN 2G4
著者Monie, T.P, Perrin, A.J, Birtley, J.R, Curry, S.
登録日2007-07-16
公開日2007-08-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights Into the Transcriptional and Translational Roles of Ebp1
Embo J., 26, 2007
3JB9
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BU of 3jb9 by Molmil
Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y.
登録日2015-08-09
公開日2015-09-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
7DGR
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BU of 7dgr by Molmil
Activity optimized supercomplex state2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
著者Jeon, T.J, Lee, S.G, Yoo, S.H, Ryu, J.H, Kim, D.S, Hyun, J.K, Kim, H.M, Ryu, S.E.
登録日2020-11-12
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex.
Antioxid.Redox Signal., 2022

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