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1D1X
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,4-PBITU (H4B BOUND)
分子名称: 2-{2-[4-(2-CARBAMIMIDOYLSULFANYL-ETHYL)-PHENYL]-ETHYL}-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L.
登録日1999-09-21
公開日2001-07-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
1CRL
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INSIGHTS INTO INTERFACIAL ACTIVATION FROM AN 'OPEN' STRUCTURE OF CANDIDA RUGOSA LIPASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIPASE
著者Grochulski, P, Cygler, M.
登録日1993-03-02
公開日1994-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Insights into interfacial activation from an open structure of Candida rugosa lipase.
J.Biol.Chem., 268, 1993
1D2F
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X-RAY STRUCTURE OF MALY FROM ESCHERICHIA COLI: A PYRIDOXAL-5'-PHOSPHATE-DEPENDENT ENZYME ACTING AS A MODULATOR IN MAL GENE EXPRESSION
分子名称: MALY PROTEIN, PYRIDOXAL-5'-PHOSPHATE
著者Clausen, T.
登録日1999-09-23
公開日2000-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structure of MalY from Escherichia coli: a pyridoxal 5'-phosphate-dependent enzyme acting as a modulator in mal gene expression.
EMBO J., 19, 2000
1CSB
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Crystal structure of cathepsin b inhibited with CA030 at 2.1 angstroms resolution: A basis for the design of specific epoxysuccinyl inhibitors
分子名称: CATHEPSIN B heavy chain, CATHEPSIN B light chain, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-isoleucyl-L-proline
著者Turk, D, Bode, W.
登録日1994-12-09
公開日1996-04-03
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors.
Biochemistry, 34, 1995
1D2V
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CRYSTAL STRUCTURE OF BROMIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BROMIDE ION, ...
著者Fiedler, T.J, Davey, C.A, Fenna, R.E.
登録日1999-09-28
公開日2000-04-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution.
J.Biol.Chem., 275, 2000
1CTS
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CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION
分子名称: CITRATE SYNTHASE, CITRIC ACID
著者Remington, S, Wiegand, G, Huber, R.
登録日1984-01-27
公開日1984-07-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution.
J.Mol.Biol., 158, 1982
1D4Z
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CRYSTAL STRUCTURE OF CHEY-95IV, A HYPERACTIVE CHEY MUTANT
分子名称: CHEMOTAXIS PROTEIN CHEY, SULFATE ION
著者Schuster, M, Zhao, R, Bourret, R.B, Collins, E.J.
登録日1999-10-06
公開日1999-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Correlated switch binding and signaling in bacterial chemotaxis.
J.Biol.Chem., 275, 2000
1D5D
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The role of phenylalanine 8 in the stabilization of the s protein-s peptide interaction: packing and cavities
分子名称: RNASE S, S PEPTIDE, SULFATE ION
著者Ratnaparkhi, G.S, Varadarajan, R.
登録日1999-10-07
公開日1999-10-20
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics.
Biochemistry, 39, 2000
1D5N
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CRYSTAL STRUCTURE OF E. COLI MNSOD AT 100K
分子名称: MANGANESE (II) ION, PROTEIN (MANGANESE SUPEROXIDE DISMUTASE)
著者Borgstahl, G.E.O, Pokross, M, Chehab, R, Sekher, A, Snell, E.H.
登録日1999-10-08
公開日2000-03-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase.
J.Mol.Biol., 296, 2000
1CZC
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ASPARTATE AMINOTRANSFERASE MUTANT ATB17/139S/142N WITH GLUTARIC ACID
分子名称: GLUTARIC ACID, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
著者Okamoto, A, Oue, S, Yano, T, Kagamiyama, H.
登録日1999-09-02
公開日2000-02-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex.
J.Biochem.(Tokyo), 127, 2000
1CZQ
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CRYSTAL STRUCTURE OF THE D10-P1/IQN17 COMPLEX: A D-PEPTIDE INHIBITOR OF HIV-1 ENTRY BOUND TO THE GP41 COILED-COIL POCKET.
分子名称: CHLORIDE ION, D-PEPTIDE INHIBITOR, FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GCN4-PIQI
著者Eckert, D.M, Malashkevich, V.N, Hong, L.H, Carr, P.A, Kim, P.S.
登録日1999-09-06
公開日1999-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.
Cell(Cambridge,Mass.), 99, 1999
1D7F
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CRYSTAL STRUCTURE OF ASPARAGINE 233-REPLACED CYCLODEXTRIN GLUCANOTRANSFERASE FROM ALKALOPHILIC BACILLUS SP. 1011 DETERMINED AT 1.9 A RESOLUTION
分子名称: CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE
著者Ishii, N, Haga, K, Yamane, K, Harata, K.
登録日1999-10-18
公開日2000-03-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of asparagine 233-replaced cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011 determined at 1.9 A resolution.
J.Mol.Recog., 13, 2000
1D9F
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CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA TETRAMER CARRYING 2'-O-(3-AMINOPROPYL)-RNA MODIFICATION 5'-D(TT)-AP(U)-D(T)-3'
分子名称: DNA POLYMERASE I, DNA/RNA (5'-D(*TP*TP)-R(*(U31)P)-D(*T)-3'), SULFATE ION, ...
著者Teplova, M, Wallace, S.T, Tereshko, V, Minasov, G, Simons, A.M, Cook, P.D, Manoharan, M, Egli, M.
登録日1999-10-27
公開日1999-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural origins of the exonuclease resistance of a zwitterionic RNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1D2K
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C. IMMITIS CHITINASE 1 AT 2.2 ANGSTROMS RESOLUTION
分子名称: CHITINASE 1
著者Hollis, T, Monzingo, A.F, Bortone, K, Ernst, S.R, Cox, R, Robertus, J.D.
登録日1999-09-23
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The X-ray structure of a chitinase from the pathogenic fungus Coccidioides immitis.
Protein Sci., 9, 2000
1CFR
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CRYSTAL STRUCTURE OF CITROBACTER FREUNDII RESTRICTION ENDONUCLEASE CFR10I AT 2.15 ANGSTROMS RESOLUTION.
分子名称: RESTRICTION ENDONUCLEASE
著者Bozic, D, Grazulis, S, Siksnys, V, Huber, R.
登録日1996-02-02
公開日1997-01-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of Citrobacter freundii restriction endonuclease Cfr10I at 2.15 A resolution.
J.Mol.Biol., 255, 1996
1CSK
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THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP
分子名称: C-SRC SH3 DOMAIN
著者Mathieu, M, Wierenga, R.K.
登録日1994-03-22
公開日1994-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop.
FEBS Lett., 341, 1994
1CRK
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MITOCHONDRIAL CREATINE KINASE
分子名称: CREATINE KINASE, PHOSPHATE ION
著者Fritz-Wolf, K, Schnyder, T, Wallimann, T, Kabsch, W.
登録日1996-03-08
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of mitochondrial creatine kinase.
Nature, 381, 1996
1D4K
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HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR
分子名称: HIV-1 PROTEASE, N-13-[(10S,13S)-9,12-DIOXO-10-(2-BUTYL)-2-OXA-8,11-DIAZABICYCLO [13.2.2] NONADECA-15,17,18-TRIENE] (2R)-BENZYL-(4S)-HYDROXY-5-AMINOPENTANOIC (1R)-HYDROXY-(2S)-INDANEAMIDE, SULFATE ION
著者Tyndall, J.D, Reid, R.C, Tyssen, D.P, Jardine, D.K, Todd, B, Passmore, M, March, D.R, Pattenden, L.K, Alewood, D, Hu, S.H, Alewood, P.F, Birch, C.J, Martin, J.L, Fairlie, D.P.
登録日1999-10-04
公開日2000-10-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease.
J.Med.Chem., 43, 2000
1D59
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CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA
分子名称: DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3')
著者Kang, C, Zhang, X, Ratliff, R, Moyzis, R, Rich, A.
登録日1992-02-25
公開日1993-04-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of four-stranded Oxytricha telomeric DNA.
Nature, 356, 1992
1D5X
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X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH DIPEPTIDE MIMETIC AND SEB
分子名称: DIPEPTIDE MIMETIC INHIBITOR, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN
著者Swain, A, Crowther, R, Kammlott, U.
登録日1999-10-12
公開日2000-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
1CK4
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CRYSTAL STRUCTURE OF RAT A1B1 INTEGRIN I-DOMAIN.
分子名称: INTEGRIN ALPHA-1
著者Nolte, M, Pepinsky, R.B, Venyaminov, S.Y, Koteliansky, V, Gotwals, P.J, Karpusas, M.
登録日1999-04-27
公開日2000-05-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain function.
FEBS Lett., 452, 1999
1D6K
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NMR SOLUTION STRUCTURE OF THE 5S RRNA E-LOOP/L25 COMPLEX
分子名称: 5S RRNA E-LOOP (5SE), RIBOSOMAL PROTEIN L25
著者Stoldt, M, Wohnert, J, Ohlenschlager, O, Gorlach, M, Brown, L.R.
登録日1999-10-14
公開日1999-11-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition.
EMBO J., 18, 1999
1CKS
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HUMAN CKSHS2 ATOMIC STRUCTURE: A ROLE FOR ITS HEXAMERIC ASSEMBLY IN CELL CYCLE CONTROL
分子名称: CYCLIN-DEPENDENT KINASE SUBUNIT, TYPE 2, SULFATE ION
著者Parge, H.E, Arvai, A.S, Tainer, J.A.
登録日1993-09-16
公開日1995-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control.
Science, 262, 1993
1CUI
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CUTINASE, S120A MUTANT
分子名称: CUTINASE
著者Martinez, C, Cambillau, C.
登録日1995-11-16
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants.
Proteins, 26, 1996
1CNJ
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X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Lesburg, C.A, Christianson, D.W.
登録日1995-04-03
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site
J.Am.Chem.Soc., 117, 1995

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