PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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4UVL	Crystal structure of human tankyrase 2 in complex with 5-amino-1,2- dihydroisoquinolin-1-one 分子名称: 5-aminoisoquinolin-1(4H)-one, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2014-08-07 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
4UVT	Crystal structure of human tankyrase 2 in complex with 5-amino-4- methyl-1,2-dihydroisoquinolin-1-one 分子名称: 5-amino-4-methylisoquinolin-1(2H)-one, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
7NUV	Crystal structure of the Aux2pLS20 tetramerization domain 分子名称: Aux2pLS20 著者 Crespo, I, Boer, D.R. 登録日 2021-03-14 公開日 2022-03-09 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural and biochemical characterization of the relaxosome auxiliary proteins encoded on the Bacillus subtilis plasmid pLS20. Comput Struct Biotechnol J, 20, 2022
5KBK	Candida Albicans Superoxide Dismutase 5 (SOD5), E110A Mutant 分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION 著者 Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J. 登録日 2016-06-03 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.411 Å) 主引用文献 The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. J.Biol.Chem., 291, 2016
6FW2	Crystal Structure of human mARC1 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MOLYBDATE ION, Mitochondrial amidoxime-reducing component 1,Endolysin,Mitochondrial amidoxime-reducing component 1, ... 著者 Kubitza, C, Scheidig, A. 登録日 2018-03-05 公開日 2018-10-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4UVV	Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methyl-1,2-dihydroisoquinolin-1-one 分子名称: 3-(4-chlorophenyl)-5-methylisoquinolin-1(2H)-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
5B7X	NMR Solution structure of an EF-hand Calcium binding protein (EhCaBP6) from Entamoeba Histolytica 分子名称: CALCIUM ION, Calmodulin, putative 著者 Verma, D, Chary, K.V. 登録日 2016-06-10 公開日 2017-05-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An Unusual Nuclear Localized Ca2+-Binding Protein from Entamoeba histolytica that Exhibits GTPase Activity To Be Published
5Z1I	Crystal structure of the protozoal cytoplasmic ribosomal decoding site in complex with 6'-fluoro sisomicin 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(fluoromethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, RNA (5'-R(P*GP*CP*GP*UP*CP*GP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') 著者 Kanazawa, H, Hanessian, S, Kondo, J. 登録日 2017-12-26 公開日 2018-05-30 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside. ChemMedChem, 13, 2018
8AW3	Cryo-EM structure of the Tb ADAT2/3 deaminase in complex with tRNA 分子名称: Deaminase, putative, RNA (75-MER), ... 著者 Dolce, L.G, Tengo, L, Weis, F, Kowalinski, E. 登録日 2022-08-29 公開日 2022-11-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Nat Commun, 13, 2022
5DQ5	Endothiapepsin in complex with fragment 209 分子名称: 3-[2-(4-methyl-1,2-oxazol-3-yl)ethyl]pyridine, ACETATE ION, Endothiapepsin, ... 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library to be published
5DPZ	Endothiapepsin in complex with fragment 31 分子名称: 2-methylaniline, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.328 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5DR7	Endothiapepsin in complex with fragment 311 分子名称: (2R)-3-cyclopropyl-2-(4-methoxyphenyl)-1,3-thiazolidin-4-one, ACETATE ION, Endothiapepsin, ... 著者 Heine, A, Schiebel, J, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.234 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
7P49	HLA-E*01:03 in complex with Mtb14 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Walters, L.C, Gillespie, G.M. 登録日 2021-07-10 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes. Cell Rep, 39, 2022
7P4B	HLA-E*01:03 in complex with IL9 分子名称: Beta-2-microglobulin, ESAT-6-like protein EsxH, GLYCEROL, ... 著者 Walters, L.C, Gillespie, G.M. 登録日 2021-07-10 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes. Cell Rep, 39, 2022
5DR1	Endothiapepsin in complex with fragment 278 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5DQ4	Endothiapepsin in complex with fragment 66 分子名称: 1-[6-(furan-2-yl)pyridin-3-yl]methanamine, Endothiapepsin, GLYCEROL 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library to be published
5DR0	Endothiapepsin in complex with fragment 203 分子名称: 1,2-ETHANEDIOL, 5-(methylsulfanyl)-4-(propan-2-ylsulfonyl)-1H-pyrazol-3-amine, ACETATE ION, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5DQ1	Endothiapepsin in complex with fragment 34 分子名称: 1,2-ETHANEDIOL, 3-[(cyclopropylamino)methyl]-8-ethylquinolin-2(1H)-one, Endothiapepsin, ... 著者 Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.489 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5DR8	Endothiapepsin in complex with fragment 330 分子名称: 2-chlorobenzohydrazide, ACETATE ION, Endothiapepsin, ... 著者 Heine, A, Knoerlein, A, Schiebel, J, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5DR3	Endothiapepsin in complex with fragment 333 分子名称: 1,2-ETHANEDIOL, 4-propan-2-ylsulfanyl-1-propyl-6,7-dihydro-5~{H}-cyclopenta[d]pyrimidin-2-one, ACETATE ION, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5HCO	Endothiapepsin in complex with hydrazide 分子名称: 4-(dimethylamino)benzohydrazide, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2016-01-04 公開日 2017-01-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
5Z1H	Crystal structure of the bacterial ribosomal decoding site in complex with 6'-fluoro sisomicin 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(fluoromethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') 著者 Kanazawa, H, Hanessian, S, Kondo, J. 登録日 2017-12-26 公開日 2018-05-30 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside. ChemMedChem, 13, 2018
5IZ1	Physcomitrella patens FBPase 分子名称: fructose-1,6-bisphosphatase 著者 Einsle, O, Guetle, D. 登録日 2016-03-24 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Chloroplast FBPase and SBPase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories. Proc.Natl.Acad.Sci.USA, 113, 2016
5KBL	Candida Albicans Superoxide Dismutase 5 (SOD5), E110Q Mutant 分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION 著者 Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J. 登録日 2016-06-03 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.414 Å) 主引用文献 The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. J.Biol.Chem., 291, 2016
5DQ2	Endothiapepsin in complex with fragment 48 分子名称: 1,2-ETHANEDIOL, Endothiapepsin, GLYCEROL, ... 著者 Radeva, N, Uehlein, M, Weiss, M, Heine, A, Klebe, G. 登録日 2015-09-14 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.514 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published

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