6TCH
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6TGV
| Crystal structure of Mycobacterium smegmatis CoaBC in complex with CTP and FMN | 分子名称: | 1,2-ETHANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, Coenzyme A biosynthesis bifunctional protein CoaBC, ... | 著者 | Mendes, V, Blaszczyk, M, Bryant, O, Cory-Wright, J, Blundell, T.L. | 登録日 | 2019-11-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nat Commun, 12, 2021
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6TLG
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6TLP
| HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6-DIBROMOBENZOTRIAZOLE | 分子名称: | 5,6-DIBROMOBENZOTRIAZOLE, CITRATE ANION, Casein kinase II subunit alpha, ... | 著者 | Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. | 登録日 | 2019-12-03 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
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1YE5
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1Y1A
| CRYSTAL STRUCTURE OF CALCIUM AND INTEGRIN BINDING PROTEIN | 分子名称: | CALCIUM ION, Calcium and integrin binding 1 (calmyrin), GLUTATHIONE | 著者 | Blamey, C.J, Ceccarelli, C, Naik, U.P, Bahnson, B.J. | 登録日 | 2004-11-17 | 公開日 | 2005-05-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structure of calcium- and integrin-binding protein 1: Insights into redox regulated functions Protein Sci., 14, 2005
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6TNC
| X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 46 | 分子名称: | CHLORIDE ION, Dual specificity protein kinase TTK, N-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | 著者 | Marquardt, T, Holton, S.J, Schulze, V.K, Klar, U, Kosemund, D, Siemeister, G, Bader, B, Prechtl, S, Briem, H, Schirok, H, Bohlmann, R, Nguyen, D, Fernandez-Montalvan, A, Boemer, U, Eberspaecher, U, Brands, M, Nussbaum, F, Koppitz, M. | 登録日 | 2019-12-06 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase. J.Med.Chem., 63, 2020
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3EWN
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6TQQ
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6T5F
| Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195 | 分子名称: | 14-3-3 protein sigma, StARD1 peptide | 著者 | Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. | 登録日 | 2019-10-16 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
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7ZJX
| Rabbit 80S ribosome programmed with SECIS and SBP2 | 分子名称: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | 著者 | Hilal, T, Simonovic, M, Spahn, C.M.T. | 登録日 | 2022-04-12 | 公開日 | 2022-09-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
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6TLK
| Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in an open conformation containing NADP+ and methylene-H4MPT | 分子名称: | 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, Bifunctional protein MdtA, CHLORIDE ION, ... | 著者 | Wagner, T, Huang, G, Demmer, U, Warkentin, E, Ermler, U, Shima, S. | 登録日 | 2019-12-02 | 公開日 | 2020-02-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. J.Mol.Biol., 432, 2020
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6OI0
| Crystal structure of human WDR5 in complex with L-arginine | 分子名称: | ARGININE, GLYCEROL, SULFATE ION, ... | 著者 | Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D. | 登録日 | 2019-04-08 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59, 2020
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1YG2
| Structure of the Vibrio cholerae virulence activator AphA | 分子名称: | gene activator AphA | 著者 | De Silva, R.S, Kovacikova, G, Lin, W, Taylor, R.T, Skorupski, K, Kull, F.J. | 登録日 | 2005-01-04 | 公開日 | 2005-01-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily J.Biol.Chem., 280, 2005
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6T80
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7ZJW
| Rabbit 80S ribosome as it decodes the Sec-UGA codon | 分子名称: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | 著者 | Hilal, T, Simonovic, M, Spahn, C.M.T. | 登録日 | 2022-04-12 | 公開日 | 2022-10-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
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6TLX
| Crystal structure of the unconventional kinetochore protein Perkinsela sp. KKT2a central domain | 分子名称: | Protein kinase, ZINC ION | 著者 | Marciano, G, Nerusheva, O, Ishii, M, Akiyoshi, B. | 登録日 | 2019-12-03 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains. J.Cell Biol., 220, 2021
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6TM3
| Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in a close conformation containing NADP+ and methylene-H4MPT | 分子名称: | 1,2-ETHANEDIOL, 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, Bifunctional protein MdtA, ... | 著者 | Wagner, T, Huang, G, Demmer, U, Warkentin, E, Ermler, U, Shima, S. | 登録日 | 2019-12-03 | 公開日 | 2020-02-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. J.Mol.Biol., 432, 2020
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6TMS
| Crystal structure of a de novo designed hexameric helical-bundle protein | 分子名称: | SULFATE ION, a novel designed pore protein, affinity purification tag | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | 登録日 | 2019-12-05 | 公開日 | 2020-04-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Computational design of transmembrane pores. Nature, 585, 2020
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6TN9
| X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 16 | 分子名称: | Dual specificity protein kinase TTK, [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | 著者 | Marquardt, T, Holton, S.J, Schulze, V.K, Klar, U, Kosemund, D, Siemeister, G, Bader, B, Prechtl, S, Briem, H, Schirok, H, Bohlmann, R, Nguyen, D, Fernandez-Montalvan, A, Boemer, U, Eberspaecher, U, Brands, M, Nussbaum, F, Koppitz, M. | 登録日 | 2019-12-06 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase. J.Med.Chem., 63, 2020
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6TND
| X-RAY STRUCTURE OF MPS1 IN COMPLEX WITH COMPOUND 79 | 分子名称: | BAY 1217389, Dual specificity protein kinase TTK | 著者 | Holton, S.J, Schulze, V.K, Klar, U, Kosemund, D, Siemeister, G, Bader, B, Prechtl, S, Briem, H, Marquardt, T, Schirok, H, Bohlmann, R, Nguyen, D, Fernandez-Montalvan, A, Boemer, U, Eberspaecher, U, Brands, M, Nussbaum, F, Koppitz, M. | 登録日 | 2019-12-06 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase. J.Med.Chem., 63, 2020
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1YFQ
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6TJ1
| Crystal structure of a de novo designed hexameric helical-bundle protein | 分子名称: | De novo designed WSHC6, purification tag | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | 登録日 | 2019-11-23 | 公開日 | 2020-04-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Computational design of transmembrane pores. Nature, 585, 2020
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1Y7U
| Crystal Structure of Acyl-Coa hydrolase from Bacillus cereus | 分子名称: | Acyl-CoA hydrolase, CALCIUM ION, COENZYME A, ... | 著者 | Kim, Y, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-12-10 | 公開日 | 2005-01-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Acyl-CoA hydrolase from Bacillus cereus To be Published
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6WTB
| Sort-Tagged Drosophila Cryptochrome | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | 著者 | Schneps, C.M, Crane, B.R. | 登録日 | 2020-05-02 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol, 4, 2021
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