PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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6FZZ	Crystal structure of BSE31 (BSPA14S_RS05060 gene product) from Lyme disease agent Borrelia (Borreliella) spielmanii 分子名称: TETRAETHYLENE GLYCOL, Virulent strain associated lipoprotein 著者 Brangulis, K, Akopjana, I, Kazaks, A, Tars, K. 登録日 2018-03-15 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione. Biochim Biophys Acta Gen Subj, 1864, 2019
5CLD	Alkylpurine DNA glycosylase AlkD bound to DNA containing an oxocarbenium-intermediate analog and a free 3-methyladenine nucleobase 分子名称: 3-METHYL-3H-PURIN-6-YLAMINE, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(NRI)P*AP*GP*TP*CP*CP*G)-3'), ... 著者 Mullins, E.A, Eichman, B.F. 登録日 2015-07-16 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.541 Å) 主引用文献 The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015
1FEB	UNLIGANDED CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT 2.0 ANGSTROM RESOLUTION 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE 著者 Strickland, C, Karplus, P. 登録日 1995-07-12 公開日 1997-01-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crithidia Fasciculata Trypanothione Reductase at 1.70 A Resolution To be Published
4K71	Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor 分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ... 著者 Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M. 登録日 2013-04-16 公開日 2013-10-23 最終更新日 2014-02-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. Structure, 21, 2013
7BAA	Cys-42-tethered stabilizer 12 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-bromanyl-3-methoxy-phenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
3FIX	Crystal structure of a putative n-acetyltransferase (ta0374) from thermoplasma acidophilum 分子名称: 1,2-ETHANEDIOL, N-ACETYLTRANSFERASE 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) 登録日 2008-12-12 公開日 2009-01-13 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production. Proteins, 79, 2011
1KNI	Stabilizing Disulfide Bridge Mutant of T4 Lysozyme 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Jacobson, R.H, Matsumura, M, Faber, H.R, Matthews, B.W. 登録日 2001-12-18 公開日 2001-12-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of a stabilizing disulfide bridge mutant that closes the active-site cleft of T4 lysozyme. Protein Sci., 1, 1992
5CNG	ultrafast dynamics in myoglobin: 150 ps time delay 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. 登録日 2015-07-17 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
7BJK	Crystal structure of the chloroplastic Fe superoxide dismutase PAP9 from Arabidopsis thaliana. 分子名称: Superoxide dismutase [Fe] 2, chloroplastic, ZINC ION 著者 Cobessi, D, Blanvillain, R, Pfannschmidt, T. 登録日 2021-01-14 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The Plastid-Encoded RNA Polymerase-Associated Protein PAP9 Is a Superoxide Dismutase With Unusual Structural Features. Front Plant Sci, 12, 2021
5CN9	Ultrafast dynamics in myoglobin: 0.4 ps time delay 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Barends, T.R.M, Foucar, L, Ardevol, A, Nass, K.J, Aquila, A, Botha, S, Doak, R.B, Falahati, K, Hartmann, E, Hilpert, M, Heinz, M, Hoffmann, M.C, Koefinger, J, Koglin, J, Kovacsova, G, Liang, M, Milathianaki, D, Lemke, H.T, Reinstein, J, Roome, C.M, Shoeman, R.L, Williams, G.J, Burghardt, I, Hummer, G, Boutet, S, Schlichting, I. 登録日 2015-07-17 公開日 2015-09-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science, 350, 2015
7B9T	Cys-45-tethered stabilizer 5 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-chlorophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)ethanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-14 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
4RTT	Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment 分子名称: SLIT-ROBO Rho GTPase-activating protein 2, SULFATE ION 著者 Opatowsky, Y, Guez-Hadad, J. 登録日 2014-11-16 公開日 2015-11-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism. Structure, 23, 2015
1KOL	Crystal structure of formaldehyde dehydrogenase 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ZINC ION, ... 著者 Tanaka, N, Kusakabe, Y, Ito, K, Yoshimoto, T, Nakamura, K.T. 登録日 2001-12-21 公開日 2002-12-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Formaldehyde Dehydrogenase from Pseudomonas putida: the Structural Origin of the Tightly Bound Cofactor in Nicotinoprotein Dehydrogenases J.mol.biol., 324, 2002
4H3U	Crystal structure of hypothetical protein with ketosteroid isomerase-like protein fold from Catenulispora acidiphila DSM 44928 分子名称: ACETATE ION, CADMIUM ION, CHLORIDE ION, ... 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) 登録日 2012-09-14 公開日 2012-10-03 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila. J.Struct.Funct.Genom., 15, 2014
7BA8	Cys-42-tethered stabilizer 10 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-methyl-2-phenoxy-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
1N42	Crystal Structure of Annexin V R149E Mutant 分子名称: Annexin V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A. 登録日 2002-10-30 公開日 2003-02-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces J.Biol.Chem., 278, 2003
6C04	Mtb RNAP Holo/RbpA/double fork DNA -closed clamp 分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. 登録日 2017-12-27 公開日 2018-03-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
4ACC	GSK3b in complex with inhibitor 分子名称: 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, DIMETHYL SULFOXIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-14 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
7BA6	Cys-42-tethered stabilizer 8 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-[3,5-bis(fluoranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
4MVK	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide fragment VFFAED 分子名称: Amyloid peptide fragment VFFAED, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
7BAB	Cys-42-tethered stabilizer 13 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-[2-chloranyl-4-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
1FLQ	HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 分子名称: LYSOZYME 著者 Masumoto, K, Ueda, T, Motoshima, H, Imoto, T. 登録日 2000-08-15 公開日 2000-09-06 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Relationship between local structure and stability in hen egg white lysozyme mutant with alanine substituted for glycine Protein Eng., 13, 2000
1FLU	HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 分子名称: LYSOZYME 著者 Masumoto, K, Ueda, T, Motoshima, H, Imoto, T. 登録日 2000-08-15 公開日 2000-09-06 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.785 Å) 主引用文献 Relationship between local structure and stability in hen egg white lysozyme mutant with alanine substituted for glycine Protein Eng., 13, 2000
4MW9	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478) 分子名称: 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
6I27	Rea1 AAA2L-H2alpha deletion mutant in AMPPNP State 分子名称: Midasin,Midasin,Midasin,Midasin,Midasin,Midasin,Midasin 著者 Sosnowski, P, Urnavicius, L, Boland, A, Fagiewicz, R, Busselez, J, Papai, G, Schmidt, H. 登録日 2018-10-31 公開日 2018-12-12 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. Elife, 7, 2018

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