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8U52
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Co-crystal structure of human transthyretin conjugated to the stilbene substructure derived from reaction with the fluorogenic covalent kinetic stabilizer A2
分子名称: S-(4-fluorophenyl) 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzenecarbothioate, Transthyretin
著者Yan, N.L, Nugroho, K, Kline, G.M, Basanta, B, Lander, G.C, Wilson, I.A, Kelly, J.W.
登録日2023-09-11
公開日2025-03-05
最終更新日2025-05-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The conformational landscape of human transthyretin revealed by cryo-EM.
Nat.Struct.Mol.Biol., 32, 2025
7YYP
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BU of 7yyp by Molmil
Structure of aIF5B from Pyrococcus abyssi complexed with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, NITRATE ION, Probable translation initiation factor IF-2
著者Bourgeois, G, Schmitt, E, Mechulam, Y, Coureux, P.D, Kazan, R.
登録日2022-02-18
公開日2022-06-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
9NI0
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L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)
分子名称: CALCIUM ION, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Fried, S.D.E, Boxer, S.G.
登録日2025-02-25
公開日2025-04-23
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase
To Be Published
1SO4
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BU of 1so4 by Molmil
Crystal structure of K64A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
9NJO
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Y100F Mutant of E. coli Dihydrofolate Reductase
分子名称: Dihydrofolate reductase, MANGANESE (II) ION
著者Fried, S.D.E, Mathews, I.I, Boxer, S.G.
登録日2025-02-27
公開日2025-05-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase
To Be Published
7NHP
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BU of 7nhp by Molmil
Structure of PSII-I (PSII with Psb27, Psb28, and Psb34)
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7NHO
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BU of 7nho by Molmil
Structure of PSII-M
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
6ORO
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BU of 6oro by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
7NHQ
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BU of 7nhq by Molmil
Structure of PSII-I prime (PSII with Psb28, and Psb34)
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7B9V
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BU of 7b9v by Molmil
Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound
分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K.
登録日2020-12-14
公開日2021-03-10
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
6ORQ
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BU of 6orq by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
3JZU
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BU of 3jzu by Molmil
Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Leu-L-Tyr
分子名称: Dipeptide Epimerase, LEUCINE, MAGNESIUM ION, ...
著者Fedorov, A.A, Fedorov, E.V, Imker, H.J, Sakai, A, Gerlt, J.A, Almo, S.C.
登録日2009-09-24
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
6WEF
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BU of 6wef by Molmil
Copper-bound D92H variant of Campylobacter jejuni P19
分子名称: COPPER (II) ION, GLYCEROL, SULFATE ION, ...
著者Chan, A.C, Murphy, M.E.
登録日2020-04-02
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献A copper site is required for iron transport by the periplasmic proteins P19 and FetP.
Metallomics, 12, 2020
1T2X
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BU of 1t2x by Molmil
Glactose oxidase C383S mutant identified by directed evolution
分子名称: ACETATE ION, COPPER (II) ION, Galactose Oxidase, ...
著者Wilkinson, D, Akumanyi, N, Hurtado-Guerrero, R, Dawkes, H, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
登録日2004-04-23
公開日2004-05-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution.
Protein Eng.Des.Sel., 17, 2004
1SJD
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BU of 1sjd by Molmil
x-ray structure of o-succinylbenzoate synthase complexed with n-succinyl phenylglycine
分子名称: N-SUCCINYL PHENYLGLYCINE, N-acylamino acid racemase
著者Thoden, J.B, Taylor-Ringia, E.A, Garrett, J.B, Gerlt, J.A, Holden, H.M, Rayment, I.
登録日2004-03-03
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
1SJB
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BU of 1sjb by Molmil
X-ray structure of o-succinylbenzoate synthase complexed with o-succinylbenzoic acid
分子名称: 2-SUCCINYLBENZOATE, MAGNESIUM ION, N-acylamino acid racemase
著者Thoden, J.B, Taylor-Ringia, E.A, Garrett, J.B, Gerlt, J.A, Holden, H.M, Rayment, I.
登録日2004-03-03
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
7BOG
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BU of 7bog by Molmil
Bacterial 30S ribosomal subunit assembly complex state E (body domain)
分子名称: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
登録日2021-01-25
公開日2021-07-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7BOH
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BU of 7boh by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state E (+RbfA)(Consensus Refinement)
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
登録日2021-01-25
公開日2021-12-08
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
1JQJ
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BU of 1jqj by Molmil
Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of the beta-delta complex
分子名称: DNA polymerase III, beta chain, delta subunit
著者Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J.
登録日2001-08-07
公開日2001-11-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
7BQO
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BU of 7bqo by Molmil
The structure of HpiI in complex with its substrate analogue
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(E,2S,4S)-2,4-dimethyloct-6-enoyl]-4-oxidanyl-1H-pyridin-2-one, GLYCEROL, ...
著者Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y.
登録日2020-03-25
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献An enzymatic Alder-ene reaction.
Nature, 586, 2020
5JRN
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BU of 5jrn by Molmil
Crystal Structure of a Xylanase in Complex with a Monosaccharide at 2.84 Angstroem resolution
分子名称: Endo-1,4-beta-xylanase, GLYCEROL, methyl beta-D-xylopyranoside
著者Gomez, S, Payne, A.M, Savko, M, Fox, G.C, Shepard, W.E, Fernandez, F.J, Vega, M.C.
登録日2016-05-06
公開日2017-05-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Structural and functional characterization of a highly stable endo-beta-1,4-xylanase from Fusarium oxysporum and its development as an efficient immobilized biocatalyst.
Biotechnol Biofuels, 9, 2016
5K33
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BU of 5k33 by Molmil
Crystal structure of extracellular domain of HER2 in complex with Fcab STAB19
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ...
著者Humm, A, Lobner, E, Goritzer, K, Mlynek, G, Obinger, C, Djinovic-Carugo, K.
登録日2016-05-19
公開日2017-04-12
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
4KY2
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BU of 4ky2 by Molmil
Transthyretin in complex with the fluorescent folding sensor (E)-7-hydroxy-3-(4-hydroxy-3,5-dimethylstyryl)-4-methyl-2H-chromen-2-one
分子名称: 7-hydroxy-3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]-4-methyl-2H-chromen-2-one, Transthyretin
著者Connelly, S, Wilson, I.A, Choi, S.
登録日2013-05-28
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors.
Chem.Commun.(Camb.), 49, 2013
8UEC
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BU of 8uec by Molmil
Structure of TREK-1CG*:CAT335a
分子名称: CADMIUM ION, DECANE, HEXADECANE, ...
著者Mondal, A, Lee, H, Minor, D.L.
登録日2023-09-30
公開日2024-06-26
最終更新日2025-01-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of covalent chemogenetic K 2P channel activators.
Cell Chem Biol, 31, 2024
7RYG
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BU of 7ryg by Molmil
A. baumannii Ribosome-TP-6076 complex: E-site tRNA 70S
分子名称: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ...
著者Morgan, C.E, Yu, E.W.
登録日2021-08-25
公開日2022-02-02
最終更新日2025-03-19
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii.
Mbio, 13, 2022

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