PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

---

3VSP	Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28 分子名称: (2R)-2-benzyl-3-[3-({[4-(piperidin-1-yl)benzoyl]amino}methyl)-4-propoxyphenyl]propanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Oyama, T, Waku, T, Ohashi, M, Morikawa, K, Miyachi, H. 登録日 2012-04-30 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28 To be Published
3QTS	CDK2 in complex with inhibitor RC-2-12 分子名称: Cyclin-dependent kinase 2, [4-amino-2-(phenylamino)-1,3-thiazol-5-yl](3-methoxyphenyl)methanone 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-23 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
3QWJ	CDK2 in complex with inhibitor KVR-1-142 分子名称: 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-chloro-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-28 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QX4	CDK2 in complex with inhibitor KVR-1-78 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-01 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QL8	CDK2 in complex with inhibitor JWS-6-260 分子名称: 1,2-ETHANEDIOL, 3-(4-amino-1,3,5-triazin-2-yl)-4-hydroxybenzonitrile, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-02 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QQJ	CDK2 in complex with inhibitor L2 分子名称: 1,2-ETHANEDIOL, 2-(4,6-diamino-1,3,5-triazin-2-yl)phenol, Cyclin-dependent kinase 2, ... 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-15 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
5U0A	CRISPR RNA-guided surveillance complex 分子名称: CRISPR-associated protein, Cas5e family, Cse1 family, ... 著者 Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. 登録日 2016-11-23 公開日 2017-08-09 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System. Cell, 170, 2017
4GIP	Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2 著者 Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A. 登録日 2012-08-08 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc.Natl.Acad.Sci.USA, 109, 2012
8U18	Cryo-EM structure of murine Thrombopoietin receptor ectodomain in complex with Tpo 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombopoietin, Thrombopoietin receptor,GCN4 isoform 1, ... 著者 Sarson-Lawrence, K.S, Hardy, J.M, Leis, A, Babon, J.J, Kershaw, N.J. 登録日 2023-08-30 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nat Commun, 15, 2024
4GMJ	Structure of human NOT1 MIF4G domain co-crystallized with CAF1 分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ... 著者 Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex Nucleic Acids Res., 40, 2012
8TQK	Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab 分子名称: Fusion glycoprotein F0, Heavy chain Fab rPIV3-18, Light chain Fab rPIV3-28 著者 Otrelo-Cardoso, A.R, Jardetzky, T.S. 登録日 2023-08-07 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Functional and structural characteristics of human monoclonal antibodies that potently neutralize human parainfluenza virus type 3 To be published
3QWK	CDK2 in complex with inhibitor KVR-1-150 分子名称: 1,2-ETHANEDIOL, 4-chloro-2-{[(2-chloropyrimidin-5-yl)methyl]amino}-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-28 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QX2	CDK2 in complex with inhibitor KVR-1-190 分子名称: 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-[(2-hydroxyethyl)amino]-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-01 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QTX	CDK2 in complex with inhibitor RC-2-35 分子名称: 4-{[4-amino-5-(3-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-23 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
8TVB	Ghanaian virus fusion glycoprotein (GhV F) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 著者 Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. 登録日 2023-08-17 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and design of Langya virus glycoprotein antigens. Proc.Natl.Acad.Sci.USA, 121, 2024
3QZI	CDK2 in complex with inhibitor KVR-1-126 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(pyrimidin-5-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-06 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
8TVH	Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ... 著者 Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. 登録日 2023-08-18 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and design of Langya virus glycoprotein antigens. Proc.Natl.Acad.Sci.USA, 121, 2024
3QZH	CDK2 in complex with inhibitor KVR-1-124 分子名称: 1,2-ETHANEDIOL, 4-methoxy-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-06 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3QXP	CDK2 in complex with inhibitor RC-3-89 分子名称: 1,2-ETHANEDIOL, 4-{[4-amino-5-(2-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-02 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
3QZF	CDK2 in complex with inhibitor JWS-6-52 分子名称: 2-(4,6-diamino-1,3,5-triazin-2-yl)benzene-1,4-diol, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-06 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
2JWT	Solution structure of Engrailed homeodomain WT 分子名称: Segmentation polarity homeobox protein engrailed 著者 Religa, T.L. 登録日 2007-10-24 公開日 2008-04-01 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Comparison of multiple crystal structures with NMR data for engrailed homeodomain J.Biomol.Nmr, 40, 2008
3R6X	CDK2 in complex with inhibitor KVR-1-158 分子名称: 1,2-ETHANEDIOL, 4-[(3-hydroxypropyl)amino]-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-22 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3R7U	CDK2 in complex with inhibitor KVR-1-75 分子名称: 1,2-ETHANEDIOL, 2-{[4-(aminomethyl)benzyl]amino}-5-nitrobenzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-23 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3R9H	CDK2 in complex with inhibitor RC-2-142 分子名称: 4-amino-N-(2,6-difluorophenyl)-2-[(4-sulfamoylphenyl)amino]-1,3-thiazole-5-carboxamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-25 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
3RPO	CDK2 in complex with inhibitor KVR-1-156 分子名称: 1,2-ETHANEDIOL, 4-({4-carbamoyl-2-nitro-5-[(pyridin-3-ylmethyl)amino]phenyl}amino)butanoic acid, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-04-27 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published

<1003100410051006100710081009101010111012101310141015101610171018>