PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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4RTZ	Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide VSL12 分子名称: GLYCEROL, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-11-16 公開日 2015-10-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.979 Å) 主引用文献 Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide VSL12 To be Published
6UCD	The crystal structure of Staphylococcus aureus super antigen-like protein SSL10 分子名称: Exotoxin 著者 Patel, D, Young, P.G, Bunker, R.D, Baker, E.N, Fraser, J.D. 登録日 2019-09-16 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The crystal structure of Staphylococcus aureus super antigen-like protein SSL10 To Be Published
6SQH	Crystal structure of mouse PRMT6 with partial C-terminal TEV cleavage site 分子名称: Protein arginine N-methyltransferase 6 著者 Bonnefond, L, Cavarelli, J. 登録日 2019-09-04 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystal structure of mouse PRMT6 in complex with inhibitors To be published
6SW2	Crystal Structure of P. aeruginosa PqsL in complex with 2-aminobenzoylacetate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(2-aminophenyl)-3-oxopropanoic acid, DI(HYDROXYETHYL)ETHER, ... 著者 Mattevi, A, Rovida, S. 登録日 2019-09-19 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer. Nat Commun, 11, 2020
4ROB	2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae 分子名称: Serpin 2 著者 Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. 登録日 2014-10-28 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae To be Published
4RTW	Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 分子名称: APP12 peptide, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-11-16 公開日 2015-10-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 To be Published
6SGV	Crystal structure of AcAChBP in complex with hosieine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Hosieine, ... 著者 Hunter, W.N, Dawson, A, Parker, H. 登録日 2019-08-05 公開日 2020-08-26 最終更新日 2022-09-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (-)-hosieine-A Acta Crystallogr.,Sect.F, 2022
6SP5	Structure of hyperstable haloalkane dehalogenase variant DhaA115 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Haloalkane dehalogenase, ... 著者 Chmelova, K, Markova, K, Damborsky, J, Marek, M. 登録日 2019-08-30 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst. Chem Sci, 11, 2020
6S7K	Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator N-(2-Methoxy-5-(N-methylsulfamoyl)phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide 分子名称: FORMIC ACID, Fumarate hydratase class II, MAGNESIUM ION, ... 著者 Whitehouse, A.J, Libardo, M.D, Kasbekar, M, Brear, P, Fischer, G, Thomas, C.J, Barry, C.E, Boshoff, H.I, Coyne, A.G, Abell, C. 登録日 2019-07-05 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Targeting of Fumarate Hydratase fromMycobacterium tuberculosisUsing Allosteric Inhibitors with a Dimeric-Binding Mode. J.Med.Chem., 62, 2019
6RUC	THE 3D STRUCTURE OF [NIFESE] HYDROGENASE G491S VARIANT FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH AT 1.20 ANGSTROM RESOLUTION 分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE (II) ION, ... 著者 Matias, P.M, Zacarias, S, Pereita, I. 登録日 2019-05-28 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.199 Å) 主引用文献 A Hydrophilic Channel Is Involved in Oxidative Inactivation of a [NiFeSe] Hydrogenase Acs Catalysis, 2019
6RV0	human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma); with PMP in the active site 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase 著者 Giardina, G, Cutruzzola, F, Cellini, B, Mirco, D. 登録日 2019-05-30 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1. Biochem.J., 476, 2019
6ULB	Sex Hormone-binding globulin mutant E176K in complex with Danazol 分子名称: CALCIUM ION, Danazol, Sex hormone-binding globulin 著者 Round, P.W, Das, S, Van Petegem, F. 登録日 2019-10-07 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and biochemical analyses of danazol interactions with sex hormone-binding globulin and effects on androgen action To Be Published
6TY7	Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-1 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... 著者 Markova, K, Chaloupkova, R, Damborsky, J, Marek, M. 登録日 2020-01-15 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers Acs Catalysis, 11, 2021
4RSQ	2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae 分子名称: Serpin 2 著者 Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. 登録日 2014-11-10 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
6UH9	Crystal structure of DAD2 D166A mutant 分子名称: Decreased Apical Dominance 2, TETRAETHYLENE GLYCOL 著者 Sharma, P, Hamiaux, C, Snowden, K.C. 登録日 2019-09-27 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners. J.Biol.Chem., 295, 2020
6UK5	Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis 分子名称: ACETATE ION, CalS10, DI(HYDROXYETHYL)ETHER, ... 著者 Alvarado, S.K, Miller, M.D, Xu, W, Wang, Z, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N. 登録日 2019-10-04 公開日 2020-10-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis To Be Published
6U4K	Human talin2 residues 1-403 分子名称: Talin-2 著者 Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K. 登録日 2019-08-26 公開日 2020-07-08 最終更新日 2020-09-23 実験手法 X-RAY DIFFRACTION (2.555 Å) 主引用文献 A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020
4RTV	Crystal structure of the Src tyrosine kinase SH3 domain S94A/Q128R mutant in complex with the high affinity synthetic peptide APP12 分子名称: APP12 peptide, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-11-16 公開日 2015-10-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Crystal structure of the Src tyrosine kinase SH3 domain S94A/Q128R mutant in complex with the high affinity synthetic peptide APP12 To be Published
4RTX	Crystal structure of the Src tyrosine kinase SH3 domain T96G/Q128R mutant 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A. 登録日 2014-11-16 公開日 2015-10-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Crystal structure of the Src tyrosine kinase SH3 domain T96G/Q128R mutant To be Published
6S7W	Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator N-(5-(Azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(quinolin-4-yl)acetamide 分子名称: FORMIC ACID, Fumarate hydratase class II, MAGNESIUM ION, ... 著者 Whitehouse, A.J, Libardo, M.D, Kasbekar, M, Brear, P, Fischer, G, Thomas, C.J, Barry, C.E, Boshoff, H.I, Coyne, A.G, Abell, C. 登録日 2019-07-07 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Targeting of Fumarate Hydratase fromMycobacterium tuberculosisUsing Allosteric Inhibitors with a Dimeric-Binding Mode. J.Med.Chem., 62, 2019
6RJE	Lysostaphin SH3b P4-G5 complex, homesource dataset 分子名称: (2~{R})-2-[[(2~{S})-2-[[(4~{R})-5-azanyl-4-[[(2~{S})-2-azanylpropanoyl]amino]-5-oxidanylidene-pentanoyl]amino]-6-[2-[2-[2-[2-(2-azanylethanoylamino)ethanoylamino]ethanoylamino]ethanoylamino]ethanoylamino]hexanoyl]amino]propanoic acid, Lysostaphin 著者 Walters-Morgan, H, Lovering, A.L. 登録日 2019-04-26 公開日 2019-10-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b. Nat.Chem.Biol., 16, 2020
6RUQ	Structure of GluA2cryst in complex the antagonist ZK200775 and the negative allosteric modulator GYKI53655 at 4.65 A resolution 分子名称: (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Krintel, C, Venskutonyte, R, Mirza, O.A, Gajhede, M, Kastrup, J.S. 登録日 2019-05-28 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.65 Å) 主引用文献 Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. Febs J., 288, 2021
6RWJ	Crystal Structure of BRD4(1) bound to inhibitor BUG0 (6) 分子名称: Bromodomain-containing protein 4, ~{N},3-dimethyl-4-oxidanylidene-5,6,7,8-tetrahydro-2~{H}-cyclohepta[c]pyrrole-1-carboxamide 著者 Huegle, M. 登録日 2019-06-05 公開日 2020-12-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines. J.Med.Chem., 63, 2020
6S7S	Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator N-(2-Methoxy-5-(N-phenylsulfamoyl)phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide 分子名称: FORMIC ACID, Fumarate hydratase class II, ~{N}-[2-methoxy-5-(phenylsulfamoyl)phenyl]-2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanamide 著者 Whitehouse, A.J, Libardo, M.D, Kasbekar, M, Brear, P, Fischer, G, Thomas, C.J, Barry, C.E, Boshoff, H.I, Coyne, A.G, Abell, C. 登録日 2019-07-05 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Targeting of Fumarate Hydratase fromMycobacterium tuberculosisUsing Allosteric Inhibitors with a Dimeric-Binding Mode. J.Med.Chem., 62, 2019
4ROA	1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae 分子名称: Serpin 2 著者 Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. 登録日 2014-10-28 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015

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