PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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6BTE	DNA Polymerase Beta I260Q Binary Complex 分子名称: CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ... 著者 Eckenroth, B.E, Doublie, S. 登録日 2017-12-06 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
1O2P	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 分子名称: 2-{5-[AMINO(IMINIO)METHYL]-6-CHLORO-1H-BENZIMIDAZOL-2-YL}-6-ISOBUTOXYBENZENOLATE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, W.F, Hui, H, Breitenbucher, G, Allen, D, Janc, J. 登録日 2003-03-06 公開日 2003-05-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors J.Mol.Biol., 329, 2003
1AXU	SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES 分子名称: DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG), N-1-AMINOPYRENE 著者 Gu, Z, Gorin, A.A, Krishnasami, R, Hingerty, B.E, Basu, A.K, Broyde, S, Patel, D.J. 登録日 1997-10-21 公開日 1998-07-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Biochemistry, 38, 1999
1O2W	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 分子名称: 2-(3-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-5-BROMO-4-OXIDOPHENYL)SUCCINATE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. 登録日 2003-03-06 公開日 2003-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. J.Mol.Biol., 329, 2003
4QVQ	yCP beta5-M45I mutant in complex with bortezomib 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-15 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
1IC2	DECIPHERING THE DESIGN OF THE TROPOMYOSIN MOLECULE 分子名称: TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE 著者 Brown, J.H, Kim, K.-H, Jun, G, Greenfield, N.J, Dominguez, R, Volkmann, N, Hitchcock-DeGregori, S.E, Cohen, C. 登録日 2001-03-29 公開日 2001-07-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Deciphering the design of the tropomyosin molecule Proc.Natl.Acad.Sci.USA, 98, 2001
7L20	Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt. 分子名称: 16S rRNA mitochondrial, 39 S P-site finger, 39S ribosomal protein L10, ... 著者 Agrawal, E, Koripella, R. 登録日 2020-12-15 公開日 2021-05-12 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance. Nat Commun, 12, 2021
1O34	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 分子名称: 2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}PYRIDIN-3-OLATE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. 登録日 2003-03-06 公開日 2003-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. J.Mol.Biol., 329, 2003
4QWI	yCP beta5-A49S-mutant in complex with carfilzomib 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-16 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
1B6V	CRYSTAL STRUCTURE OF A HYBRID BETWEEN RIBONUCLEASE A AND BOVINE SEMINAL RIBONUCLEASE 分子名称: RIBONUCLEASE 著者 Vatzaki, E.H, Allen, S.C, Leonidas, D.D, Acharya, K.R. 登録日 1999-01-18 公開日 1999-06-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution. Eur.J.Biochem., 260, 1999
1O3B	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 分子名称: 3-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-1,1'-BIPHENYL-2-OLATE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. 登録日 2003-03-06 公開日 2003-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. J.Mol.Biol., 329, 2003
1UGH	CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE IN COMPLEX WITH A PROTEIN INHIBITOR: PROTEIN MIMICRY OF DNA 分子名称: PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR), PROTEIN (URACIL-DNA GLYCOSYLASE) 著者 Mol, C.D, Arvai, A.S, Sanderson, R.J, Slupphaug, G, Kavli, B, Krokan, H.E, Mosbaugh, D.W, Tainer, J.A. 登録日 1999-02-05 公開日 1999-02-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. Cell(Cambridge,Mass.), 82, 1995
1B87	CRYSTAL STRUCTURE OF AN AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE 分子名称: ACETYL COENZYME *A, PROTEIN (AMINOGLYCOSIDE N6'-ACETYLTRANSFERASE TYPE 1) 著者 Wybenga-Groot, L.E, Berghuis, A.M. 登録日 1999-02-09 公開日 1999-06-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold. Structure Fold.Des., 7, 1999
4EG1	Trypanosoma brucei methionyl-tRNA synthetase in complex with substrate Methionine 分子名称: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ... 著者 Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2012-03-30 公開日 2012-09-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20, 2012
6BQJ	CRYSTAL STRUCTURE OF HEPATIS C VIRUS PROTEASE (NS3) COMPLEXED WITH TRIPEPTIDIC ACYL SULFONAMIDE INHIBITOR (COMPOUND 16) 分子名称: ACETATE ION, CHLORIDE ION, N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(2S)-1-[(cyclopropylsulfonyl)amino]-4,4-difluoro-1-oxobutan-2-yl}-4-[(7-methoxy-2-phenylquinolin-4-yl)oxy]-L-prolinamide, ... 著者 Klei, H.E, Sack, J.S. 登録日 2017-11-28 公開日 2018-03-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor. ACS Med Chem Lett, 9, 2018
5DLC	X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa 分子名称: PHOSPHATE ION, Pyridoxine 5'-phosphate synthase 著者 Fairman, J.W, Abendroth, J, Lorimer, D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-09-04 公開日 2015-09-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa To Be Published
2XER	Human PatL1 C-terminal domain (loop variant with sulfates) 分子名称: PAT1 HOMOLOG 1, SULFATE ION 著者 Tritschler, F, Weichenrieder, O. 登録日 2010-05-17 公開日 2010-06-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa. Embo J., 29, 2010
2XK1	Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor 分子名称: COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, ... 著者 Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. 登録日 2010-07-07 公開日 2011-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors Acs Med.Chem.Lett., 2, 2011
5FUI	Crystal structure of the C-terminal CBM6 of LamC a marine laminarianse from Zobellia galactanivorans 分子名称: 2-AMINOMETHYL-PYRIDINE, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ... 著者 Labourel, A, Jam, M, Legentil, L, Sylla, B, Hehemann, J.H, Ficko-Blean, E, Ferrieres, V, Czjzek, M, Michel, G. 登録日 2016-01-27 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Unraveling the Multivalent Binding of a Marine Family 6 Carbohydrate-Binding Module with its Native Laminarin Ligand. FEBS J., 283, 2016
4EJI	Human Cytochrome P450 2A13 in complex with two molecules of 4-(methylnitrosamino)-1-(3-puridyl)-1-butanone 分子名称: 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one, Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE 著者 DeVore, N.M, Scott, E.E. 登録日 2012-04-06 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes. J.Biol.Chem., 287, 2012
4R3R	Crystal structures of EGFR in complex with Mig6 分子名称: Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1' 著者 Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J. 登録日 2014-08-17 公開日 2015-08-12 最終更新日 2015-09-16 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat.Struct.Mol.Biol., 22, 2015
1IBJ	Crystal structure of cystathionine beta-lyase from Arabidopsis thaliana 分子名称: CARBONATE ION, CYSTATHIONINE BETA-LYASE, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Breitinger, U, Clausen, T, Messerschmidt, A. 登録日 2001-03-28 公開日 2001-04-04 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity Plant Physiol., 126, 2001
1AYX	CRYSTAL STRUCTURE OF GLUCOAMYLASE FROM SACCHAROMYCOPSIS FIBULIGERA AT 1.7 ANGSTROMS 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUCOAMYLASE 著者 Sevcik, J, Hostinova, E, Gasperik, J, Solovicova, A, Wilson, K.S, Dauter, Z. 登録日 1997-11-12 公開日 1998-05-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of glucoamylase from Saccharomycopsis fibuligera at 1.7 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
6BXL	Crystal structure of Pyrococcus horikoshii Dph2 with 4Fe-4S cluster and SAM 分子名称: 2-(3-amino-3-carboxypropyl)histidine synthase, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE 著者 Torelli, A.T, Fenwick, M.K, Zhang, Y, Dong, M, Kathiresan, V, Carantoa, J.D, Dzikovski, B, Lancaster, K.M, Freed, J.H, Hoffman, B.M, Lin, H, Ealick, S.E. 登録日 2017-12-18 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science, 359, 2018
5FOT	HUMANISED MONOMERIC RADA IN COMPLEX WITH FHTU TETRAPEPTIDE 分子名称: DNA REPAIR AND RECOMBINATION PROTEIN RADA, FHTU PEPTIDE, PHOSPHATE ION 著者 Scott, D.E, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. 登録日 2015-11-26 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.189 Å) 主引用文献 Structure Activity Relationship of the Peptide Binding Motif Mediating the Rad51:Brca2 Protein-Protein Interaction. FEBS Lett., 590, 2016

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