7BHO
 
 | | DNA origami signpost designed model | | 分子名称: | DNA, DNA scaffold | | 著者 | Silvester, E, Vollmer, B, Prazak, V, Vasishtan, D, Machala, E.A, Whittle, C, Black, S, Bath, J, Turberfield, A.J, Gruenewald, K, Baker, L.A. | | 登録日 | 2021-01-11 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (36.439999 Å) | | 主引用文献 | DNA origami signposts for identifying proteins on cell membranes by electron cryotomography.
Cell, 184, 2021
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7BVU
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6NLF
 | | 1.45 A resolution structure of apo BfrB from Pseudomonas aeruginosa | | 分子名称: | Ferroxidase, POTASSIUM ION | | 著者 | Lovell, S, Punchi-Hewage, A, Battaile, K.P, Yao, H, Nammalwar, B, Gnanasekaran, K.K, Bunce, R.A, Reitz, A.B, Rivera, M. | | 登録日 | 2019-01-08 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.
J.Am.Chem.Soc., 141, 2019
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7BL4
 | | in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | | 登録日 | 2021-01-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
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6Z6F
 | | HDAC-PC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
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2AWI
 | | Structure of PrgX Y153C mutant | | 分子名称: | PrgX | | 著者 | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.k, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | | 登録日 | 2005-09-01 | | 公開日 | 2005-12-06 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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7BL6
 | | 50S-ObgE-GMPPNP particle | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | | 登録日 | 2021-01-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
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6Z6O
 | | HDAC-TC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
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6Z6H
 | | HDAC-DC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (8.55 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
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7C1O
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7BL3
 | | pre-50S-ObgE particle state 2 | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | | 登録日 | 2021-01-18 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
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6NOP
 | | Structure of Cyanothece McdA(D38A)-ATP complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | | 著者 | Schumacher, M.A. | | 登録日 | 2019-01-16 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
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2GGC
 | | Novel bacterial methionine aminopeptidase inhibitors | | 分子名称: | COBALT (II) ION, METHIONINE, Methionine aminopeptidase, ... | | 著者 | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | | 登録日 | 2006-03-23 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Proteins, 66, 2007
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6Z6P
 | | HDAC-PC-Nuc | | 分子名称: | DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
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6TA5
 | | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | | 分子名称: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | | 著者 | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | | 登録日 | 2019-10-29 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
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7BB7
 | | AVP-V2R-Galphas-beta1-gamma2-Nb35(T state) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C. | | 登録日 | 2020-12-17 | | 公開日 | 2021-06-02 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Sci Adv, 7, 2021
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2GAI
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2AGX
 | | Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. P212121 form | | 分子名称: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | | 著者 | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | | 登録日 | 2005-07-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Atomic description of an enzyme reaction dominated by proton tunneling
Science, 312, 2006
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7BM5
 | | Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1 | | 分子名称: | Fab1 heavy chain, Fab1 light chain | | 著者 | White, P, Storek, K.M, Rutherford, S.T, Radford, S.E. | | 登録日 | 2021-01-19 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding.
Nat Commun, 12, 2021
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7BB6
 | | AVP-V2R-Galphas-beta1-gamma2-Nb35 (L state) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C. | | 登録日 | 2020-12-17 | | 公開日 | 2021-06-02 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Sci Adv, 7, 2021
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2AIE
 | | S.pneumoniae polypeptide deformylase complexed with SB-505684 | | 分子名称: | HYDROXY[3-(6-METHYLPYRIDIN-2-YL)PROPYL]FORMAMIDE, NICKEL (II) ION, Peptide deformylase, ... | | 著者 | Smith, K.J, Petit, C.M, Aubart, K, Smyth, M, McManus, E, Jones, J, Fosberry, A, Lewis, C, Lonetto, M, Christensen, S.B. | | 登録日 | 2005-07-29 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Variation and inhibitor binding in polypeptide deformylase from four different bacterial species
Protein Sci., 12, 2003
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2B0Q
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2AO2
 | | The 2.07 Angstrom crystal structure of Mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactions | | 分子名称: | Chorismate mutase, SULFATE ION, TRYPTOPHAN | | 著者 | Qamra, R, Prakash, P, Aruna, B, Hasnain, S.E, Mande, S.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2005-08-12 | | 公開日 | 2006-06-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions.
Biochemistry, 45, 2006
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6NR6
 | | Crystal Structure of Staphylococcus pseudintermedius SbnI in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional transcriptional regulator/O-phospho-L-serine synthase SbnI, MAGNESIUM ION | | 著者 | Verstraete, M.M, Morales, L.D, Kobylarz, M.J, Loutet, S.A, Laakso, H.A, Heinrichs, D.E, Murphy, M.E.P. | | 登録日 | 2019-01-22 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus .
J.Biol.Chem., 294, 2019
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7BJX
 | | Crystal structure of CHK1-10pt-mutant complex with compound 26 | | 分子名称: | 4-amino-7-methyl-2-[(1-methyl-1H-pyrazol-4-yl)amino]-6-[(2R)-2-methylpyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Serine/threonine-protein kinase Chk1 | | 著者 | Dokurno, P, Surgenor, A.E, Williamson, D.S. | | 登録日 | 2021-01-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design and Synthesis of Pyrrolo[2,3- d ]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate.
J.Med.Chem., 64, 2021
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