5XJC
| Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | 登録日 | 2017-04-30 | 公開日 | 2017-07-05 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
|
|
6TED
| Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | 分子名称: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | 著者 | Vos, S.M, Farnung, L, Cramer, P. | 登録日 | 2019-11-11 | 公開日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
|
|
3H0G
| RNA Polymerase II from Schizosaccharomyces pombe | 分子名称: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | 登録日 | 2009-04-09 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5XON
| RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | 分子名称: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | 登録日 | 2017-05-29 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | 主引用文献 | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
|
|
6TQO
| rrn anti-termination complex | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
|
|
6TQN
| rrn anti-termination complex without S4 | 分子名称: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
|
|
6VZ3
| Escherichia coli transcription-translation complex D2 (TTC-D2) containing mRNA with a 27 nt long spacer | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
5X4Z
| RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | 著者 | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | 登録日 | 2017-02-14 | 公開日 | 2017-05-17 | 実験手法 | X-RAY DIFFRACTION (7.8 Å) | 主引用文献 | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
|
|
5X8R
| Structure of the 30S small subunit of chloroplast ribosome from spinach | 分子名称: | 16S rRNA, 30S ribosomal protein S1, chloroplastic, ... | 著者 | Ahmed, T, Shi, J, Bhushan, S. | 登録日 | 2017-03-03 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
|
|
6VZ5
| Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VU3
| Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R. | 登録日 | 2020-02-14 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
5X8P
| Structure of the 70S chloroplast ribosome from spinach | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Ahmed, T, Shi, J, Bhushan, S. | 登録日 | 2017-03-03 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
|
|
6VZJ
| Escherichia coli transcription-translation complex A1 (TTC-A1) containing mRNA with a 15 nt long spacer, fMet-tRNAs at E-site and P-site, and lacking transcription factor NusG | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-28 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VYZ
| Escherichia coli transcription-translation complex C6 (TTC-C6) containing mRNA with a 21 nt long spacer, NusA, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VYR
| Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 18 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VYT
| Escherichia coli transcription-translation complex A2 (TTC-A2) containing a 15 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H, Su, M. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VZ2
| Escherichia coli transcription-translation complex D1 (TTC-D1) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
6VYU
| Escherichia coli transcription-translation complex C2 (TTC-C2) containing a 27 nt long mRNA spacer | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
|
|
3H3V
| Yeast RNAP II containing poly(A)-signal sequence in the active site | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... | 著者 | Dengl, S, Cramer, P. | 登録日 | 2009-04-17 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
|
|
5XOG
| RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1 | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (30-MER), DNA (39-MER), ... | 著者 | Ehara, H, Shirouzu, M, Sekine, S. | 登録日 | 2017-05-28 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
|
|
3HOV
| Complete RNA polymerase II elongation complex II | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
|
|
3HOW
| Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | 分子名称: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
|
|
3HKZ
| |
3I4M
| 8-oxoguanine containing RNA polymerase II elongation complex D | 分子名称: | DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Damsma, G.E, Cramer, P. | 登録日 | 2009-07-02 | 公開日 | 2009-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular basis of transcriptional mutagenesis at 8-oxoguanine J.Biol.Chem., 284, 2009
|
|
3HOY
| Complete RNA polymerase II elongation complex VI | 分子名称: | 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... | 著者 | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | 登録日 | 2009-06-03 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
|
|