8F2Q
 
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6WX7
 | | SOX2 bound to Importin-alpha 2 | | 分子名称: | Importin subunit alpha-1, Transcription factor SOX-2 | | 著者 | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | | 登録日 | 2020-05-09 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
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4UAE
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8Q8K
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3TJ3
 | | Structure of importin a5 bound to the N-terminus of Nup50 | | 分子名称: | Importin subunit alpha-1, Nuclear pore complex protein Nup50 | | 著者 | Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G. | | 登録日 | 2011-08-23 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.
J.Biol.Chem., 287, 2012
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8FUB
 | | Crystal structure of human Importin alpha 3 in complex with Hendra virus matrix protein NLS1 | | 分子名称: | Importin subunit alpha-3, Matrix protein | | 著者 | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | | 登録日 | 2023-01-17 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
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7UWO
 | | Structure of beta-catenin in complex with FP05874, a Helicon Polypeptide | | 分子名称: | Catenin beta-1, Helicon Polypeptide FP05874, N,N'-(1,4-phenylene)diacetamide | | 著者 | Agarwal, S, Thomson, T, Wahl, S, Ramirez, J, Hriniak, B, Verdine, G, McGee, J. | | 登録日 | 2022-05-03 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
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3TX7
 | | Crystal structure of LRH-1/beta-catenin complex | | 分子名称: | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2 | | 著者 | Yumoto, F, Fletterick, R. | | 登録日 | 2011-09-22 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structural basis of coactivation of liver receptor homolog-1 by beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4R11
 | | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | | 分子名称: | Cadherin-related hmr-1, IODIDE ION, Protein humpback-2 | | 著者 | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | | 登録日 | 2014-08-03 | | 公開日 | 2015-04-29 | | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | | 主引用文献 | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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1BK6
 | | KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | | 分子名称: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | | 著者 | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
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6IW8
 | | Crystal structure of Importin-alpha and wild-type GM130 | | 分子名称: | Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 | | 著者 | Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. | | 登録日 | 2018-12-04 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha.
Nat Commun, 10, 2019
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1IQ1
 | | CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX | | 分子名称: | IMPORTIN ALPHA-2 SUBUNIT | | 著者 | Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B. | | 登録日 | 2001-05-28 | | 公開日 | 2001-11-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
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1EJL
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6WX9
 | | SOX2 bound to Importin-alpha 5 | | 分子名称: | Importin subunit alpha-5, Transcription factor SOX-2 | | 著者 | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | | 登録日 | 2020-05-10 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
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7F7O
 | | APC-Asef FP assay tracer | | 分子名称: | Adenomatous polyposis coli protein, N-[3',6'-bis(oxidanyl)-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-5-yl]methanethioamide, Tracer 7 | | 著者 | Yang, X, Zhang, J. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The tracer of FP assay for screening APC-Asef inhbitors
To Be Published
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1O6O
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7CRU
 | | hnRNPK NLS in complex with Importin alpha 1 (KPNA2) | | 分子名称: | ACETATE ION, GLYCEROL, Heterogeneous nuclear ribonucleoprotein K, ... | | 著者 | Yao, J, Sun, Q. | | 登録日 | 2020-08-14 | | 公開日 | 2021-11-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Cell.Mol.Life Sci., 78, 2021
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8Y14
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8Z5J
 | | Beta-catenin Crystal Structure | | 分子名称: | Catenin beta-1 | | 著者 | Tim, F. | | 登録日 | 2024-04-18 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 2024
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3IFQ
 | | Interction of plakoglobin and beta-catenin with desmosomal cadherins | | 分子名称: | E-cadherin, SULFATE ION, plakoglobin | | 著者 | Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I. | | 登録日 | 2009-07-24 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
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5EKG
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1O6P
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1XM9
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1F59
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7LEU
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