PDB: 510 件ウェブページステータス検索Chemie searchBIRD

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4F5I	Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5H	Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5L	A Theoretical Optimized Mutant for the Conversion of Substrate Specificity and Activity of Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P7. 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-05-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Janus: an algorithm for ranking functional importance of residues from protein sequence alignments. To be Published
4F4E	Crystal structure of Aromatic-amino-acid aminotransferase from Burkholderia pseudomallei covalently bound to pyridoxal phosphate 分子名称: 1,2-ETHANEDIOL, Aromatic-amino-acid aminotransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-05-10 公開日 2012-05-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Aromatic-amino-acid aminotransferase from Burkholderia pseudomallei covalently bound to pyridoxal phosphate To be Published
4EU1	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-25 公開日 2012-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
4EMY	Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. 分子名称: Aminotransferase class I and II, PYRIDOXAL-5'-PHOSPHATE 著者 Chang, C, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-04-12 公開日 2012-05-09 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. TO BE PUBLISHED
4EFF	Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei 分子名称: Aromatic-amino-acid aminotransferase, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-29 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei To be Published
4DQ6	Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Putative pyridoxal phosphate-dependent transferase 著者 Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-02-15 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of putative aminotransferase from Clostridium difficile 630 to be published
4DGT	Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate 分子名称: CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-01-26 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of putative aminotransferase from Clostridium difficile 630 to be published
4DBC	Substrate Activation in Aspartate Aminotransferase 分子名称: (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate aminotransferase, ... 著者 Toney, M.D, Fisher, A.J, Griswold, W.R. 登録日 2012-01-14 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase. J.Am.Chem.Soc., 134, 2012
3UE8	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ... 著者 Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R. 登録日 2011-10-28 公開日 2012-02-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia. ACS Med Chem Lett, 3, 2012
3TQX	Structure of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl) from Coxiella burnetii 分子名称: 2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
4A00	Structure of an engineered aspartate aminotransferase 分子名称: ALANYL-PYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, DI(HYDROXYETHYL)ETHER, ... 著者 Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. 登録日 2011-09-06 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold. Biocim.Biophys.Acta, 1824, 2011
3ZZK	Structure of an engineered aspartate aminotransferase 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, GLYCEROL, ... 著者 Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. 登録日 2011-09-01 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold. Biocim.Biophys.Acta, 1824, 2011
3ZZJ	Structure of an engineered aspartate aminotransferase 分子名称: ASPARTATE AMINOTRANSFERASE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. 登録日 2011-09-01 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold. Biocim.Biophys.Acta, 1824, 2011
3TCM	Crystal Structure of Alanine Aminotransferase from Hordeum vulgare 分子名称: Alanine aminotransferase 2, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE 著者 Rydel, T.J, Sturman, E.J, Halls, C, Chen, S, Zeng, J, Evdokimov, A, Duff, S.M.G. 登録日 2011-08-09 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure. Arch.Biochem.Biophys., 528, 2012
3T32	Crystal structure of a putative C-S lyase from Bacillus anthracis 分子名称: Aminotransferase, class I/II 著者 Anderson, S.M, Wawrzak, Z, Gordon, E, Peterson, S.N, Porebski, P, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-07-24 公開日 2011-08-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a putative C-S lyase from Bacillus anthracis TO BE PUBLISHED
3B1C	Crystal structure of betaC-S lyase from Streptococcus anginosus: Internal aldimine form 分子名称: BetaC-S lyase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Kezuka, Y, Yoshida, Y, Nonaka, T. 登録日 2011-06-29 公開日 2012-06-27 最終更新日 2014-01-22 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3B1D	Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: External aldimine form 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BetaC-S lyase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Kezuka, Y, Yoshida, Y, Nonaka, T. 登録日 2011-06-29 公開日 2012-06-27 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3B1E	Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: alpha-Aminoacrylate form 分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... 著者 Kezuka, Y, Yoshida, Y, Nonaka, T. 登録日 2011-06-29 公開日 2012-06-27 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3AV7	Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-hydroxyquinoline-2-carboxylic acid, ... 著者 Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S. 登録日 2011-02-23 公開日 2012-03-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural insight into kynurenic acid excretion mechanisms of kynurenine aminotransferase in the hyperthermophilic archaeon Pyrococcus horikoshii To be Published
3QPG	Crystal Structures of Escherichia coli Aspartate Aminotransferase Reconstituted with 1-Deaza-Pyridoxal 5'-Phosphate: Internal Aldimine and Stable L-Aspartate External Aldimine 分子名称: (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate transaminase, ... 著者 Griswold, W.R. 登録日 2011-02-13 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structures of Aspartate Aminotransferase Reconstituted with 1-Deazapyridoxal 5'-Phosphate: Internal Aldimine and Stable l-Aspartate External Aldimine. Biochemistry, 50, 2011
3QN6	Crystal Structures of Escherichia coli Aspartate Aminotransferase Reconstituted with 1-Deaza-Pyridoxal 5'-Phosphate: Internal Aldimine and Stable L-Aspartate External Aldimine 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, SULFATE ION 著者 Griswold, W.R. 登録日 2011-02-08 公開日 2011-06-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structures of Aspartate Aminotransferase Reconstituted with 1-Deazapyridoxal 5'-Phosphate: Internal Aldimine and Stable l-Aspartate External Aldimine. Biochemistry, 50, 2011
3QGU	L,L-Diaminopimelate aminotransferase from Chlamydomonas reinhardtii 分子名称: AZIDE ION, GLYCEROL, LL-diaminopimelate aminotransferase, ... 著者 Dobson, R.C.J, Giron, I, Hudson, A.O. 登録日 2011-01-25 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development Plos One, 6, 2011
3ATH	Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with four AKGs as substrates and allosteric effectors 分子名称: 2-OXOGLUTARIC ACID, PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein PH0207 著者 Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S. 登録日 2011-01-05 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine To be Published

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